Sentences with phrase «ancestral proteins»

Strong functional patterns in the evolution of eukaryotic genomes revealed by the reconstruction of ancestral protein domain repertoires.

My research attempts to integrate these methods in order to investigate important questions in evolution: reconstructing ancestral protein sequences and determining the functional roles of proteins existing in organisms early in the history of life.

Bioinformatician Thomas Rattei, University of Vienna, and physicist Hernan Makse, City University New York (CUNY), have reconstructed ancestral protein networks.

How is it possible to resurrect ancestral protein?

It is also possible that some functions of W01A8.1 protein forms may be related to a proposed ancestral protein acting differently than mammalian perilipins as was suggested by Beller et al. (2010).

Since K. lactis did not undergo the whole genome duplication that S. cerevisiae did, the idea is that KlOrc1p represents the multifunctional ancestral protein (or at least what it has evolved into over the past 100 million years or so).

«This adds to the evidence that the ability of ancestral proteins to access different conformations, and not structural stability, is important for their potential to evolve new functions,» Ortlund says.

He found that the ancestral protein has all the amino acids but tryptophan, suggesting that its addition was the finishing touch to the genetic code.

'' The properties of these ancestral proteins (Precambrian β - lactamases) confer high structural stability and promiscuous enzymatic activity, meaning that they are capable of reacting with a variety of substances.

By comparing today's sequences to each other within an evolutionary framework, scientists can reasonably infer the sequence of an ancestral protein from which the modern versions descended using models of sequence evolution.

This discovery begs the question of how these ancestral proteins operate and whether understanding their function can yield new insight into the evolution of eukaryote cells and the transition of cytoskeletal machinery from archaea to eukaryotes.