Sentences with phrase «ancient horse genomes»

Thus, the ancient horse genomes offer an unprecedented opportunity to investigate changes associated with domestication.
We therefore sequenced two ancient horse genomes from Taymyr, Russia (at 7.4 - and 24.3-fold coverage), both predating the earliest archeological evidence of domestication.
They compared these ancient horse genomes with already published genomes of 18 ancient and 28 modern horses.
Subsequent genetic studies have supported the NCC deficit hypothesis, most recently an April report in Science on the sequencing of 14 ancient horse genomes up to 4,100 years old; that's close to the estimated dawn of domesticated horses some 5,500 years ago.

Not exact matches

And since the cost of genome sequencing has plummeted to one - thousandth of its initial cost, it's clear that the Neanderthal, a 700,000 - year - old horse and the woolly mammoth will simply be the first of many ancient genomes to be sequenced.
It is the latest in a series of breakthroughs in ancient DNA, coming just months after the sequencing of the oldest - ever genome, from a 700,000 - year - old horse.
New techniques and very old bones overcome the limits of genome sequencing for prehistoric horses, ancient cave bears, and even our own early ancestors.
But in 2013, ultramodern DNA extraction and sequencing techniques enabled researchers to access ancient genetic codes and translate their evolutionary tales: Researchers in Denmark reconstructed a record - breaking 700,000 - year - old horse genome, and geneticists in Germany began parsing the DNA of 400,000 - year - old hominids.
Whole genome sequencing of modern and ancient horses unveils the genes that have been selected by humans in the process of domestication through the latest 5,500 years, but also reveals the cost of this domestication.
This transformation left specific signatures in the genomes of modern horses, which the ancient genomes helped reveal.
We therefore decided to sequence the genome of ancient horses that lived prior to domestication to directly assess how pre-domesticated horses looked like genetically.»
This is something that was only detectable in the horse in comparison to the ancient genomes, as Przewalski's horses were found to show a proportion of deleterious mutations similar to domesticated horses.
This was apparent in the increasing levels of inbreeding found amongst domesticates, but also through an enhanced accumulation of deleterious mutations in their genomes relative to the ancient wild horses.
Researchers have also delved into the genomes of ancient animals — the oldest so far is a 700,000 - year - old horse.
This new work, which hints that other horses may be represented in these ancient genomes, shows «that [horse] domestication could have been a process with many phases, experiments, failures, and successes,» says Ernest Bailey, a geneticist at the University of Kentucky's Gluck Equine Research Center in Lexington.
Genomes from ancient horses show the genetic changes wrought by domestication — and their costs.
The sequenced genome offers a glimpse at the ancient horse and how equine genes have evolved.
Such tracks were also found among domesticated horses but were almost absent from the ancient genomes (Fig. 4A and SI Appendix, Figs.
The mitochondrial genome sequences of the two ancient horses clustered within the extensive diversity present in modern horses, as previously reported (9, 12, 25).
This analysis revealed a statistically significant excess of shared derived polymorphisms between the ancient and domesticated horses in the following quartets (Przewalski's, Domesticated; Ancient, Donkey), where «Domesticated» represents any of the six domesticated horse genomes included in this study (SI Appendix, sectionancient and domesticated horses in the following quartets (Przewalski's, Domesticated; Ancient, Donkey), where «Domesticated» represents any of the six domesticated horse genomes included in this study (SI Appendix, sectionAncient, Donkey), where «Domesticated» represents any of the six domesticated horse genomes included in this study (SI Appendix, section S2.7).
These ancient genomes reveal predomestic population structure and a significant fraction of genetic variation shared with the domestic breeds but absent from Przewalski's horses.
In a recent study, researchers from the University of Copenhagen compared the complete genomes of nine living and two ancient Yakutian horses from Far East Siberia with the genomes of 27 modern domesticated horses.
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