Sentences with phrase «androgen hormone stimulation»

However, cancer cells often generate abnormal forms of the androgen receptor that can be switched on all the time without the need for androgen hormone stimulation.

Not exact matches

Furthermore, high blood levels of insulin can act by increasing androgenous hormonal stimulation of the ovarian theca cells as well as potentiating gonadotropin - stimulated ovarian androgen steroidogenesis — although recent data has suggested that the insulin - induced increase in ovarian hormone secretion is not accompanied by increased steroid metabolism.74 Hyperinsulinaemia may also affect the central actions of androgen by impairing progesterone inhibition of the gonadotropin - releasing hormone pulse generator.75 Insulin has also been shown to increase expression of adrenal steroidogenic enzyme mRNA47 as well as adrenal responsiveness to adrenocorticotropic hormone.76