Sentences with phrase «androgen levels result»

However, the current methods to reduce androgen levels result in a number of serious problems.

Not exact matches

A variable disorder that is marked especially by amenorrhea, hirsutism, obesity, infertility, and ovarian enlargement and is usually initiated by an elevated level of luteinizing hormone, androgen, or estrogen which results in an abnormal cycle of gonadotropin release by the pituitary gland — abbreviation PCOS — called also polycystic ovary disease, polycystic ovary syndrome, polycystic ovary disease, Stein - Leventhal syndrome.

Common conventional treatment is androgen deprivation therapy (ADT), which drastically reduces testosterone levels resulting in many distressing side effects, such as sexual dysfunction.

When testosterone is given, the need to compensate via increased production of 5α - DHT is removed; the androgen receptors are now also being activated by testosterone, resulting in signaling for reduced synthesis of 5α - reductase and / or reduced 5α - reductase activity.41 In sum, the research suggests that testosterone replacement promotes normalization of 5α - reductase activity, 5α - DHT levels and its metabolism to 3β - adiol.

Venturella et al showed that 2 g / day of MYO for six months resulted in significant weight loss and improved HDL and LDL levels.48 MYO at 1,200 mg / day for 12 weeks significantly decreased androgens and insulin in non-obese women with PCOS.