In this study, we focused on PC3 cells, which lack
androgen receptor expression, are completely undifferentiated, are highly tumorigenic and metastatic, and have been considered the most malignant prostate cancer cell line (27 — 29).
«But what we show is that even triple negative breast cancers with lower
androgen receptor expression critically depend on the androgen receptor and may benefit from anti-androgen receptor therapy.
Triple negative breast cancers were recently divided into further subtypes including a subtype with high
androgen receptor expression (Lehmann, JCI 2011).
Not exact matches
Mice that won home or away showed increased
expression of the
receptors for the male hormone
androgen in a region of the brain that influences social aggression.
Growth hormone (GH)
receptors in prostate cancer: gene
expression in human tissues and cell lines and characterization, GH signaling and
androgen receptor regulation in LNCaP cells.
(2) Evaluation of AR (
Androgen Receptors)
Expression in Progressive Metastatic Prostate Cancer Patients Treated with Anti-androgenic Drug: 18F - DHT (18F - 16beta - fluoro - 5alpha - dihydrotestosterone)