Sentences with phrase «aneuploidy at»

Preimplantation genetic screening for aneuploidy at our Virginia fertility center can help hopeful parents avoid passing debilitating genetic disorders to their children.

Not exact matches

Since his appointment at the University of Heidelberg in 1997, Duesberg has spent each of the last 10 summers in Mannheim down the hall from Hehlmann, conducting experiments in cancer and aneuploidy.

But in a paper published in the journal Cell, researchers at the Koch Institute for Integrative Cancer Research at MIT reveal that aneuploidy alone can cause this significant variability in traits, in otherwise genetically identical cells.

Today in the journal Cancer Cell, Cold Spring Harbor Laboratory (CSHL) Fellow Jason Sheltzer, Ph.D., and colleagues at CSHL and MIT report surprising results of experiments intended to explore the consequences of having too many or too few chromosomes, a phenomenon that biologists call aneuploidy (AN - you - ploid - ee).

In contrast to the view that aneuploidy is deleterious, the aneuploid unisexually generated isolates MN35 (n +113) and MN55 (n +19) were as virulent as the euploid wild - type parent, despite their modest TS growth at 37 °C on YPD rich media in vitro (Figure 7).

«The authors went on to study the resulting blastocysts for aneuploidy (frequency of abnormal chromosomes), and pattern of gene expression (which genes are active and at what level).

The team's work highlights this by presenting a comprehensive view of genome evolution on many different levels (e.g., differences in ploidy, aneuploidy, genetic variants, hybridization, and introgressions) that is difficult to obtain at the same scale and accuracy for other eukaryotic organisms.

Each mouse autosome is present in at least two Robertsonian chromosomes, so that these stocks can be used to generate specific aneuploidies for each of the 19 mouse autosomes.

Leishmania lacks classical regulation of transcription at initiation through promoters, so aneuploidy could represent a major adaptive strategy of this parasite to modulate gene dosage in response to stressful environments.

Quote from the abstract,» This is an interesting observation as it is assumed that aneuploidy is a key event in cancer induction and at present no other aneugenic plant - derived substances of dietary relevance are known.»