Sentences with phrase «aneuploidy during»
Here we use two different mutant conditions to address the consequences of aneuploidy during tissue development and homeostasis in Drosophila.
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Aneuploidy occurs when parts of chromosomes beyond the normal 46 are missing or added to a person's genetic material during cell division.
Aneuploidy originates during cell division, when the chromosomes do not separate properly or are not equally partitioned between the two daughter cells.
Partly based on his MIT Ph.D. thesis research performed in yeast, Sheltzer suspects aneuploidy causes errors in DNA replication, as well as problems with chromosome segregation during cell division.
Using Plk4 overexpression (PLK4OE) during epidermal development, we assess the impact of centrosome amplification and aneuploidy on skin development and tumorigenesis.
The efficient compaction of DNA during cellular division ensures equal distribution of DNA into daughter cells and prevents aneuploidy, which has been implicated as a major driver of tumor development.