Sentences with phrase «angiotensin receptor»

Drugs such as ACE - inhibitors and angiotensin receptor blockers can benefit cats with chronic kidney disease by dilating blood vessels and supporting blood flow through the kidneys, lowering blood pressure, and also significantly reducing protein loss through the kidneys which can lead to the progression of disease, and so potentially improve survival in these patients.

Semintra is an angiotensin receptor blocker for use in cats suffering from chronic kidney disease.

The two groups of drugs that are in most common use for that in pets are angiotensin receptor blocking medications (ACE inhibitors, eg Fortekor ®, Lotensin ®, Enalapril ® aka ACE - Is)(ref1, rptref2, ref3) and angiotensin receptor blockers (ARBs such as telmisartan / Semintra ®).

George L. Bakris, M.D., of University of Chicago Medicine, and colleagues randomly assigned 823 patients (821 received study drug) with diabetes and elevated albuminuria who were receiving an angiotensin - converting enzyme inhibitor or angiotensin receptor blocker to varying doses of the drug finerenone or placebo.

Molecular characterization of new selective peroxisome proliferator - activated receptor gamma modulators with angiotensin receptor blocking activity.

Using 2006 - 11 data from Medicare's Part D drug benefit, the study found that 60 percent of patients with heart problems who saw a cardiologist received ACE inhibitors or angiotensin receptor blockers, versus 44 percent of those who didn't see a cardiologist.

«Building off of our knowledge that these autoantibodies cause chronic inflammation, we decided to look at a class of medications, angiotensin receptor blockers, that block inflammation and are commonly prescribed to lower blood pressure,» says Peter M. Abadir, M.D., associate professor of medicine at the Johns Hopkins University School of Medicine and the paper's lead author.

Results of a new study led by Johns Hopkins researchers offer new evidence for a strong link between angiotensin receptor autoantibodies and increased risk of frailty.

Current therapies include surgery, for example replacing the weakened part of the aorta, and medical treatments such as beta - blockers or angiotensin receptor blockers.

Not exact matches

For example, the treatment of hypertension went through several significant changes from the days of the a-adrenoceptor antagonists to that of the latest generation of angiotensin - converting enzyme inhibitors and angiotensin II receptor blockers.

Two classes of blood pressure medications, angiotensin - converting enzyme inhibitors (ACEIs) and angiotensin II receptor blockers (ARBs), are associated with a 16 % lower risk of strokes, heart attacks and death in patients with end - stage renal disease who are undergoing peritoneal dialysis, a new study in the journal, Nephrology Dialysis Transplantation, reports.

There is also hope surrounding the prophylactic effect on migraine attacks from newer substances such as angiotensin - converting enzyme and angiotensin II receptor antagonists — especially candesartan.

Moreover, stimulation of the angiotensin II type 1A receptor activated JNK3 and triggered the colocalization of β - arrestin 2 and active JNK3 to intracellular vesicles.

Some scientists suspect that it might bind to the angiotensin - converting enzyme 2 (ACE2) receptor, as did the SARS virus.

The blood pressure medication angiotensin - converting enzyme inhibitors (ACEIs) appear to reduce major cardiovascular events and death, as well death from all other causes, in patients with diabetes, while angiotensin II receptor blockers (ARBs) appear to have no such effect on those outcomes.

When allergists advised patients to avoid raw produce and switched from ACE inhibitors to angiotensin II receptor blocker (ARB) therapy, no further oral allergy symptoms occurred.

Abadir and colleagues experimented with gel formulations of angiotensin II receptor antagonists, or blockers, a long - standing class of drugs that includes losartan and valsartan, prescribed to treat hypertension.

Symposia and poster abstracts will focus on reactive oxidant stress, nitric oxide, angiotensin II, angiotensin (1 - 7), glutamate, GABA and the transcriptional and translational regulation of the receptors for many of these mediators.

Interplay between EGR1 and SP1 is critical for 13 - cis retinoic acid - mediated transcriptional repression of angiotensin type 1A receptor.

C - terminal processing of GABARAP is not required for trafficking of the angiotensin II type 1A receptor.

G protein - coupled receptor kinase and β - arrestin - mediated desensitization of the angiotensin II type 1A receptor elucidated by diacylglycerol dynamics.

Di - acidic Motifs in the Membrane - distal C Termini Modulate the Transport of Angiotensin II Receptors from the Endoplasmic Reticulum to the Cell Surface.

The Angiotensin II Type 1 Receptor C - Terminal Lys Residues Interact with Tubulin and Modulate Receptor Export Trafficking.

Cell - penetrating peptides corresponding to the angiotensin II type 1 receptor reduce receptor accumulation and cell surface expression and signaling.

Transient receptor potential (TRP) protein 7 acts as a G protein - activated Ca 2 + channel mediating angiotensin II - induced myocardial apoptosis.

Tannic Acid Down - Regulates the Angiotensin Type 1 Receptor Through a MAPK - Dependent Mechanism.

Regulation of anterograde transport of adrenergic and angiotensin II receptors by Rab2 and Rab6 GTPases.

Endoplasmic reticulum export of adrenergic and angiotensin II receptors is differentially regulated by Sar1 GTPase.

Angiotensin II receptor type 1 (Agtr1a): Lowering Agtr1a protein levels protects mitochondrial function and modestly extends life in mice, though as for many of these methods of somewhat slowing aging there are probably many other changes to the operation of metabolism that are as yet unexplored.

Mechanisms of Dopamine D1 and Angiotensin Type 2 Receptor Interaction in Natriuresis.

Intracellular angiotensin II fusion protein alters AT1 receptor fusion protein distribution and activates CREB.

13 - cis - Retinoic acid specific down - regulation of angiotensin type 1 receptor in rat liver epithelial and aortic smooth muscle cells.

The trafficking protein GABARAP binds to and enhances plasma membrane expression and function of the angiotensin II type 1 receptor.

Rab1 GTPase regulates phenotypic modulation of pulmonary artery smooth muscle cells by mediating the transport of angiotensin II type 1 receptor under hypoxia.

Pharmacologic Effects of 2 - Methoxyestradiol on Angiotensin Type 1 Receptor Down - Regulation in Rat Liver Epithelial and Aortic Smooth Muscle Cells % U http://www.sciencedirect.com/science/article/pii/S1550857912000484.

Distinct Pathways for the Trafficking of Angiotensin II and Adrenergic Receptors from the Endoplasmic Reticulum to the Cell Surface.

Expression of a naturally occurring angiotensin AT1 receptor cleavage fragment elicits caspase - activation and apoptosis.

β - Arrestin 2 - dependent angiotensin II type 1A receptor - mediated pathway of chemotaxis.

Both angiotensin II receptors are important drug targets, since the blockade of AT1R has anti-hypertensive effects, while the modulation of AT2R could be useful for cardioprotection, neuropathic pain relief and the treatment of several other conditions.

Beta - blockers and diuretics are most often associated with diabetes, and angiotensin - receptor blockers (ARBs) and angiotensin - converting - enzyme (ACE) inhibitors are least associated with it.

The inflammation occurs when at - risk cells produce receptors called All (known as angiotensin II type I receptors).

Effects of angiotensin - converting enzyme inhibitors and angiotensin - II type - 1 receptor antagonists in rats with heart failure