Sentences with word «anhydrase»

Risk may be higher with long - term treatment (12) and concurrent use of carbonic anhydrase inhibitors such as topiramate or zonisamide (24).

Children on carbonic anhydrase inhibitor medications (for example, topiramate or zonisamide) may have increased risk of excess ketosis and metabolic acidosis on commencing ketogenic therapy (2).

A micromotor covered with the enzyme carbonic anhydrase zips through water rapidly converting dissolved carbon dioxide to the bicarbonate ion, which can then be precipitated as calcium carbonate.

van Karnebeek CD, Sly WS, Ross CJ, Salvarinova R, Yaplito - Lee J, Santra S, Shyr C, Horvath GA, Eydoux P, Lehman AM, Bernard V, Newlove T, Ukpeh H, Chakrapani A, Preece MA, Ball S, Pitt J, Vallance HD, Coulter - Mackie M, Nguyen H, Zhang LH, Bhavsar AP, Sinclair G, Waheed A, Wasserman WW, Stockler - Ipsiroglu S. Mitochondrial carbonic anhydrase VA deficiency resulting from CA5A alterations presents with hyperammonemia in early childhood.

At approximately the 1 tonne - CO2 / day scale, the testing involved the use of CO2 Solutions» proprietary 1T1 carbonic anhydrase enzyme to efficiently capture CO2 from both natural gas and coal combustion flue gases.

Carbonic anhydrase inhibitors such as acetazolamide (Diamox; Lederle laboratories) also decrease CSF flow and may also be helpful in treating syringomyelia although adverse effects of abdominal pain, lethargy and weakness may limit long term use.).

He also worked to synthesize inhibitors and activators of carbonic anhydrases, a family of enzymes important in the hydrolysis of carbon dioxide in living tissues.

Their test tube experiments suggest that the resulting molecule behaves in almost exactly the same way as natural carbonic anhydrase.

The researchers have already changed eight of charybdotoxin's amino acids to recreate the active portion of the enzyme carbonic anhydrase, which is essential for plant and animal respiration.

UTC, for its part, is developing a membrane system based on the chemistry of carbonic anhydrase that, although not zero cost, saves 30 percent of the energy that would be needed to capture carbon with amines or other known chemistries.

That structure allows the carbonic anhydrase to grip the CO2 «not too loose and not too tight,» Cordatos explained, which is critical for efficiently capturing and then releasing the greenhouse gas.

But carbonic anhydrase «captures 600 molecules every second,» Cordatos said at the ARPA - E summit in Washington, D.C., last week.

The key to this metabolic process is an enzyme called carbonic anhydrase and it's efficiency at capturing and releasing CO2 is what human engineers want to mimic at the power plant scale.

A team of researchers led by the Department of Energy's Oak Ridge National Laboratory used neutron macromolecular crystallography to investigate the different states of three glaucoma drugs as they interact with the targeted enzyme, human carbonic anhydrase II (hCA II).

Using X-ray crystallography, McKenna and his students Jenna Driscoll and Brian Mahon have taken this work a step further by determining how saccharin binds to carbonic anhydrase IX, and how it or other saccharin - based compounds might be tweaked to enhance this binding and boost its anti-cancer treatment potential.

So far, finding a substance that blocks carbonic anhydrase IX without affecting the other ones has been elusive.

Not only did it reduce the amount of saccharin needed to inhibit carbonic anhydrase IX, the compound was 1,000 times more likely to bind to the enzyme than saccharin.

The new work examines how saccharin binds to and deactivates carbonic anhydrase IX, a protein found in some very aggressive cancers.

Carbonic anhydrase IX is similar to other carbonic anhydrase proteins that our bodies need to work properly.

In earlier work, scientists from a group led by Claudiu T. Supuran, Ph.D., at the University of Florence, Italy, discovered that saccharin inhibits the actions of carbonic anhydrase IX, but not the 14 other carbonic anhydrase proteins that are vital to our survival.

Carbonic anhydrase IX helps regulate pH in and around cancer cells, allowing tumors to thrive and potentially metastasize to other parts of the body.

Except for in the gastrointestinal tract, carbonic anhydrase IX is normally not found in healthy human cells.

These microorganisms contain microcompartments named carboxysomes that encapsulate Rubisco in a protein shell and contain an enzyme, carbonic anhydrase (CA), which converts bicarbonate ion to CO2.

Cancer cells can not exist without trans - membrane carbonic anhydrases, which regulate pH inside and around the cancer cells.

Reber, F., Gersch, U., Funk, R.H. Blockers of carbonic anhydrase can cause increase of retinal capillary diameter, decrease of extracellular and increase of intracellular pH in rat retinal organ culture.

Another gene that is involved in the transport of CaCO3 reactants is the carbonic anhydrase, which has been identified and characterized by molecular biology, biochemistry and pharmacology techniques (reviewed in Bertucci et al., 2013).

Key words: Stylophora pistillata; inorganic carbon; biomineralization; CO2 - concentrating - mechanism; Carbonic anhydrase.

Carbonic anhydrase IX is an independent predictor of survival in advanced renal clear cell carcinoma: implications for prognosis and therapy.

Complementation of the yeast deletion mutant Delta NCE103 by members of the beta class of carbonic anhydrases is dependent on carbonic anhydrase activity rather than on antioxidant activity

The micromotors have an outer polymer surface that holds the enzyme carbonic anhydrase, which speeds up the reaction between carbon dioxide and water to form bicarbonate.

The tobacco salicylic acid - binding protein 3 (SABP3) is the chloroplast carbonic anhydrase, which exhibits antioxidant activity and plays a role in the hypersensitive defense response

To make matters worse, soy inhibits a zinc - containing enzyme known as carbonic anhydrase, which helps transport gases across the intestinal wall.

If carbonic anhydrase is neutralized, gas builds up in the colon.

Acetazolamide and methazolamide are inhibitors of the enzyme carbonic anhydrase, which is required for the production of CSF.

Our technology, inspired by nature, utilizes the extremely powerful enzyme catalyst which efficiently manages carbon dioxide in humans and other living organisms, carbonic anhydrase.

CO2 Solution has developed a process that relies on the enzyme carbonic anhydrase to extract carbon dioxide from the smokestacks of coal power and industrial plants.

Once bicarbonate ions are imported and concentrated, the conversion to CO2 is also accelerated by the ubiquitous enzyme carbonic anhydrase.

Although this upwelling deceases surface pH and provides more CO2, diatoms still rely on bicarbonate transporters and carbonic anhydrase to ensure an adequate supply of CO2 for photosynthesis.

CO2 Solutions takes an alternative approach by using a powerful carbon management catalyst — the natural enzyme carbonic anhydrase.

They loaded the membrane with a natural enzyme called carbonic anhydrase — naturally found in mammal muscles, blood and lungs to dispose of carbon dioxide.

Genes putatively related to calcification (e.g. calcium and inorganic carbon transport, H + transport and carbonic anhydrases) have been identified via gene expression studies comparing calcifying and non-calcifying E. huxleyi cells [25 — 29], or in short - term experiments where calcification was regulated by limitation of ions needed for calcification (i.e. Ca2 +, HCO3 − / CO32 − [26,30,31]-RRB-.