Cellular Studies (CEL): The study of
animal cells involving the use of microscopy to study cell structure and studies investigating activity within cells such as enzyme pathways, cellular biochemistry, and synthesis pathways for DNA, RNA, and protein.
Not exact matches
The increasing use of in - vitro - fertilisation techniques, and the emergence of new possibilities
involving human cloning, mixing of human and
animal genetic elements, and the use of embryonic stem
cells for research, among other things, brought the need for further teaching.
The objects of his study range from a class of molecules that have the basic self - duplicating property of living things, through
cells which suggest purely physical systems, through
animals which give increasing evidence of having minds, to human beings in whom streams of consciousness seem to
involve continual choices of action, at the opposite pole from control by impersonal laws of nature.
«In
animal studies, exercise has been shown to specifically affect the hippocampus, significantly increasing the growth of new neurons and
cell survival, enhancing memory and learning, and increasing molecules that are
involved in the plasticity of the brain,» Chaddock said.
Bar coding typically
involves sequencing a few short segments of
animal DNA from the mitochondria, the mini-organs that produce energy within every
cell.
► The U.S. National Institutes of Health (NIH) has put funding on hold for experiments that
involve «mixing human stem
cells into very early
animal embryos and letting them develop» while it «reconsiders its rules» for this type of research, Gretchen Vogel reported Wednesday.
In unpublished research, Cagan (now at the Wellcome Trust Sanger Institute in Hinxton, England) found that genes
involved in helping neural crest
cells migrate differed between the tame and wild
animals (SN: 6/13/15, p. 11).
But Pearse had shown that no virus was
involved; the cancer
cells had transferred directly from one
animal to the next.
The report, from a committee made up of 11 members of Parliament, also recommends legalizing research
involving embryos of chimeras and hybrids, which includes
cells created by fusing human and
animal nuclei.
In earlier studies
involving animal models and human cancer
cell lines, researchers found that breast cancer spreads when three specific
cells are in direct contact: an endothelial
cell (a type of
cell that lines the blood vessels), a perivascular macrophage (a type of immune
cell found near blood vessels), and a tumor
cell that produces high levels of Mena, a protein that enhances a cancer
cell's ability to spread.
I mean, you know, the people that are
involved in this, you know, imagine a future where, you know, you can take some stem
cells from a farm
animal, grow them and produce meat.
The study suggests there may be «many more such instances of misidentification of
animal species» — especially considering that the sunfish is relatively large and hard to miss — says Byrappa Venkatesh, a geneticist at the Institute of Molecular and
Cell Biology in Singapore, who was not
involved in the new research.
With chronically infected mice as their model, the researchers used a new technology called ATAC - seq to map the regulatory regions of the genome — the sections of DNA
involved in switching genes on and off — in the
animals» exhausted and functional CD8 + T
cells.
In most
animals, nutrition
involves components specialized in the regulation of nutritional supply and demand (in most
animals, for example, the brain controls the needs of the body
cells).
The human kidney
cell involved survived the experience, and though we are a long way from the laser eyes of Cyclops from the X-Men franchise, the achievement suggests that «living lasers» might be created inside live
animals.
Also, while many of the genes
involved in basic
cell functions are the same in this plant and
animals, the set of genes for
cell - to -
cell communication vary dramatically between the two kingdoms.»
Indiana University scientists have discovered the first known instance of a plant or
animal lacking several key genes
involved in energy production in
cells.
Some
animals, such as the axolotl salamander, can regrow new body parts in a process that
involves the generation of new
cells.
While assisted reproductive techniques such as intracytoplasmic sperm injection (ICSI)-- which
involves the direct injection of sperm into the egg
cell — can overcome head or tail abnormalities in sperm, recent
animal research suggests that fertility doctors must use these techniques with care.
But these trials
involve cells that were originally created using
animal products for research.
Chimeras that combine
animal and human
cells, especially those that
involve pluripotent human
cells, raise ethical questions, however.
The researchers administered drugs to block neurotransmitters common to humans, frogs and other
animals: GABA - A, which is responsible mainly for inhibiting nerve
cells from firing, and glutamate receptors (AMPA and NMDA), which are
involved primarily in exciting neurons to fire.
The solution was targeted to each
animal's striatum, a brain region
involved in motor control; it is the dopamine - producing nerve
cells in this area that die during Parkinson's disease.
Stem
cell technology has advanced so much that scientists can grow miniature versions of human brains — called organoids, or mini-brains if you want to be cute about it — in the lab, but medical ethicists are concerned about recent developments in this field
involving the growth of these tiny brains in other
animals.
John O'Keefe, along with John Dostrovsky, discovered in 1971 that the hippocampus contains special nerve
cells that are
involved in determining an
animal's specific location, which they called place
cells.
Current efforts, mostly conducted in
animal models,
involve attempting to derive and aggregate embryonic stem
cells, exposing them to such factors as acetic acid, allowing them to differentiate, or specialize, and then sorting through these
cells to extract the
cell types of interest.
We need to study brain activity at neural resolution in
animals to understand the
cell - types and microcircuitry
involved.
Supplies: The amount of money requested for supplies should be divided into major research supply categories (e.g.,
cell biology reagents, test fees, etc.) If
animals are to be
involved, the justification should state how many are to be used, their unit purchase price, and their unit care cost.
In this interview, Dr. Haller discusses the possibility of utilizing stem
cells to generate new kidneys, including using
animal models to understand the pathways
involved, 3D bio-printing and the timeline to the clinic.
Federal officials are proposing to end a moratorium on funding for research that
involves transplanting human stem
cells into
animal embryos, a controversial practice that produces organisms know as «chimeras.»
Others including Randy Schekman had discovered NSF to be important for vesicle trafficking and secretion in yeast, leading Rothman to argue that these proteins are
involved in vesicle fusion in every
cell of the
animal kingdom — a universal mechanism for secretion.
The Society believes that research
involving the transfer of a human nucleus into an
animal egg will lead to important new knowledge about
cell nuclear replacement (CNR) technology and, if it were to prove possible to produce embryonic stem
cells by this route, would increase understanding of how to programme these
cells to develop into different tissue types.
The
cell types
involved in diabetes — the beta and immune
cells — are being studied in the culture dish, as well as transplanted into lab
animals.
• Disease - driving pathways that
involve the human immune system are often targeted by antibodies, and Organ - Chips recreate complex interactions of different human
cell types and aspects of the human immune system, overcoming limitations of
animal models which do not reflect all human immune
cells.
Cell culture studies
involve removing tissue (or even individual
cells) from a plant or
animal and growing them in a laboratory environment.
In 2013, Peterson and his colleagues Joanna Yeh and Keith Joung were first to use the new technology to engineer a new strain of
animal — a zebra - fish missing the GSK3ß gene, which encodes an enzyme
involved in energy metabolism and the development of
cell and body structures as an embryo grows.
The work in humans is complemented by laboratory work
involving cell death in Parkinson's disease, effects of stimulation on hippocampal neurogenesis and
animal models of deep brain stimulation.
In
animal studies — and particularly in studies
involving the gastrointestinal tract and colorectal cancer — intake of isothiocyanates has been shown to inhibit growth of existing cancer
cells and to be protective against the formation of such
cells.
Treatment for these one
celled animals involves giving medications daily for one to two weeks.
Primarily used for racehorses, the procedure
involves removing
cells from an
animal, harvesting stem
cells and then injecting them at the injury site.
«Because Vetericyn products do not contain antibiotics, they can not be overused and the
animal will never build up a resistance... [alcohol has] been shown to damage
cells and healthy tissue
involved in wound repair,» she explains.
Some
animals, such as the axolotl salamander, can regrow new body parts in a process that
involves the generation of new
cells.
Published articles address a broad range of subjects relating to the kidney and urinary tract, and may
involve human or
animal models, individual
cell types, and isolated membrane systems.