Sentences with phrase «animal disease models closely»

Since 2006 when Biomedcode was established, we have evaluated hundreds of therapeutics including novel biologics, biosimilars, biobetters and small molecules using a unique array of animal disease models closely mimicking the complexity of human inflammatory conditions.

Not exact matches

One of the most promising avenues for developing a cure, however, is through gene therapy, and to create those therapies requires animal models of disease that closely replicate the human condition.

The investigators used the nanoparticle plus the iRGD to deliver irinotecan in a robust animal model for pancreatic cancer that closely mimics human disease.

Before that happens, he says, researchers must show it works in animal models that more closely mimic human diseases.

If the marriage of stem cells and CRISPR follows a similar path, it might not be long before pigs have enough Homo sapiens in them not only to grow human hearts, lungs, livers, and kidneys for transplant but also to model human diseases more closely than current lab animals do and to test experimental drugs.

This animal model closely resembles lesion kinetics as seen in human disease [34] and use of non-human primates allows for repetitive surgical sampling for multiple time point analysis.

By tweaking an animal's DNA or using other means to inflict changes in their cells and tissues, some organisms can closely model human diseases.

With all stages of clinical Lyme disease having previously been described in nonhuman primates, this animal model was selected in order to most closely mimic human infection and response to treatment.

The pathogenesis, disease course, and treatment response of cOSA closely parallels that of human pediatric OSA (hOSA), and it has thus been proposed as a spontaneous animal model of the disease.