Cold Spring Harbor, NY — Scientists at Cold Spring Harbor Laboratory (CSHL) have made important progress in understanding the earliest steps in a process that protects
animal genomes from potentially dangerous genetic elements called transposons.
Not exact matches
These conclusions stemmed
from an initial observation that many limb control elements, or limb enhancers, found in limbed
animals are still present in snake
genomes.
The differences they found in the cat
genome help explain characteristics such as why cats are almost exclusively carnivorous and how their vision and sense of smell differ
from other
animals like dogs.
However, the results of more recent phylogenetic analyses, derived
from comparisons between sequences of specific genes and of whole
genomes, seemed to point to Ctenophora as the first group that parted company with the lineage
from which the rest of the
animal kingdom (including sponges) evolved.
But everything we're learning
from the human and
animal genome projects, about the conservation of neurochemistries and the neuroanatomies, all of this points me to the conclusion that we are learning about ourselves when we study these little critters.»
With a grant
from the Morris
Animal Foundation, Antczak, his collaborators Samantha Brooks and Ann Staiger
from the University of Florida, and the rest of the team applied a genomewide association study to compare the genetic makeup of horses with and without sarcoid tumors at more than 50,000 sites in the equine
genome.
«Our vision is to apply the same approach but rapidly screen non-synthetic, biological or «natural» molecules cloned
from human or other
genomes, including those of plants,
animals and microbes,» he said.
The sequencing of the oldest mammalian
genome from an ancient polar bear jawbone provides clues about these
animals» fraught relationship with climate change
They analyzed more than 2000 different mitochondrial
genomes from animals, plants, fungi, and protists (like amoebas).
The odds are that Dolly's
genome came
from a differentiated cell, but the quest for the best way to create cloned
animals continues.
It represents only a small fraction of an
animal's
genome (the rest is nuclear DNA), and because it is transmitted only
from the mother, it reveals just the genetic history of females.
From a bat's wings to an elephant's cancer resistance, an interdisciplinary team of scientists at University of Utah Health are using
animals» unique traits to pinpoint regions of the human
genome that might affect health.
Earlier studies looked at many genes
from a few
animals or a few genes
from many
animals, but Brown University biologist Casey Dunn and his team cast a wider net, sampling DNA
from all across the
genomes of 71 different
animals.
A new look at a virtual zoo - full of
animals,
from hummingbirds to bats to elephants, suggests that many vertebrate
genomes have the same accordion - like properties.
Dalén and colleagues extracted DNA
from a rib bone and deciphered the
animal's entire genetic makeup, its
genome.
Scientists at the University of Tübingen have now managed to isolate mitochondrial
genomes (mtDNA)
from deer bones found in the Swabian Alb that are 12,000 years old which sheds light on how prevalent these
animals were in southern Germany.
They would then use CRISPR and other gene - editing tools to swap relevant genes
from the extinct
animal into the living species and implant the hybrid
genome into a surrogate (or grow it in an artificial womb).
Using a database of wildlife
genomes that have already been sequenced and tissue samples taken
from living
animals or carcasses, the team identified DNA sequences that are unique to manatee.
Scientists have been attempting to link traits that distinguish domesticated
animals from their wild relatives to specific changes in their
genomes.
His adviser at the time,
animal genomicist Martien Groenen of Wageningen University and Research Centre in the Netherlands, had sequenced these
genomes and had gathered additional, albeit less complete, genetic data
from 600 other wild and domesticated pigs as part of another study.
WASHINGTON, D.C. — A 2 - day National Academy of Sciences (NAS) workshop here last week exposed just how far scientists, ethicists, and regulators are
from agreeing on the best way to move forward with
genome editing in
animals.
The new genomic catalog contains nearly 200 viral
genomes collected
from patient samples in Sierra Leone and Nigeria, as well as field samples
from the major
animal reservoir, or host, of Lassa virus — the rodent Mastomys natalensis, also called the multimammate rat.
The genes that have been lost
from V. scurruloideum typically reside in the mitochondrial
genomes of plants and
animals.
University of Nevada, Reno researchers, led by College of Science Assistant Professor David Alvarez - Ponce, have analyzed 322
animal genome sequences
from the National Center for Biotechnology Information looking for
animals that show the presence of active CMAH genes.
The researchers sequenced the
genomes of 43 different CC97 isolates
from humans, cattle, and other
animals, and plotted their genetic relationships in a phylogenetic tree.
They placed the data
from the 322
animal genomes into a «tree» to determine when in an
animal's evolutionary history did the CMAH gene became inactive or «turned off.»
Constructing a family tree for three lizard species collected in Panama at the Smithsonian Tropical Research Institute (STRI) and a fourth
from the southeastern U.S., scientists at Arizona State University compared lizard
genomes — their entire DNA code — to those of other
animals.
Ordering DNA
from commercial outfits has become as easy as ordering pizza, according to Voigt, who projects that in upcoming decades scientists will be able to whip up much larger segments of DNA: synthetic
genomes for yeast,
animals — perhaps even humans.
For each specimen, they sequenced 685 bases
from the fastest - mutating part of the
animal's mitochondrial
genome and then assessed the genetic diversity of ancient herds.
The sequencing of the human
genome (ScienceNOW, 14 April 2003:) gave scientists major new insights into what makes us human: Although we share more than 98 % of our genetic code with the chimpanzee, natural selection has turned us into a very different
animal than the chimps,
from whom our hominid ancestors split evolutionarily some 6 million years ago (ScienceNOW, 31 August).
Samples of cRNA derived
from single
animals were hybridized in recommended buffer to microarrays (Murine
Genome Array U74Av2, Affymetrix Inc.) at 45 °C for 16 hours.
A proteome - based phylogeny shows that the amoebozoa diverged
from the
animal - fungal lineage after the plant -
animal split, but Dictyostelium seems to have retained more of the diversity of the ancestral
genome than have plants,
animals or fungi.
Do the portions of our
genomes that set us apart
from other
animals hold the secret to human evolution?
Scientific meeting «Gene targeting,
genome editing & transgenesis: research application» We are organizing joint meeting with our colleagues
from Masaryk University in Brno dedicated to current progress in transgenic technologies in research application,
animal models of diseases and Wnt signalling.
He and colleagues Lawrence Grossman and Derek Wildman compared approximately 10,000 protein coding genes culled
from the dolphin
genome with comparable genes
from 9 other
animals: a cow, horse, dog, mouse, human, elephant, opossum, platypus and chicken.
Although the diversity of sponges and their uncertain phylogeny make it doubtful that any single species can reveal the intricacies of early
animal evolution, comparison of the A. queenslandica draft
genome with sequences
from other species can provide a conservative estimate of the
genome of the common ancestor of all
animals and the timing and nature of the genomic events that led to the origin and early evolution of
animal lineages.
Here we present the draft
genome sequence of Amphimedon queenslandica, a demosponge
from the Great Barrier Reef, and show that it is remarkably similar to other
animal genomes in content, structure and organization.
Control of pathogens arising
from humans, livestock and wild
animals can be enhanced by
genome - based investigation.
Many successful assembly applications of the Pacific Biosciences technology have been reported ranging
from small bacterial
genomes to large plant and
animal genomes.
On a safari through the
genome — genes offer new insights into the distribution of giraffes (17/11/2014) A team
from the LOEWE Biodiversity and Climate Research Center (BiK - F), in conjunction with the Giraffe Conservation Foundation, has conducted a detailed analysis of these
animals» spatial distribution based on their genetic profile....
Termed «ultraconserved elements» or UCEs, these portions of the
genome have remained unchanged for 300 to 500 million years, appearing in the same state across multiple
animal species —
from humans to dinosaurs to platypuses.
They contribute blood, cell samples, etc.
from their own
animals to help with DNA and
genome studies.
It received funding support
from the National Human
Genome Research Institute, National Science Foundation, Morris
Animal Foundation, European Research Council, Spanish government, Winn Feline Foundation, and National Center for Research Resources.
Anicka Yi goes deep into the body's biochemistry in her hypnotic 3D travelogue video The Flavour
Genome, following a «bioprospecting» trip through the Amazon jungle in search of «designed chemical personas» that can be extracted
from plant and
animal life.
The film, based on a Michael Crichton novel, was itself inspired by actual scientific breakthroughs in the early 1990s that allowed scientists to use DNA
from museum specimens and fossils to recreate the
genome — or genetic blueprint — of dead
animals.