Sentences with phrase «animal models including»

In 2017, it will be joined by Anipath, a platform devoted to the histological analysis of small animal models including phenotyping, diagnosis of morbidity cause, in situ gene expression studies.

CELPHEDIA WP1 workgroup gathers experts using CRISPR / Cas9 system in various animal models including mouse, rat, zebrafish and drosophila.

Not exact matches

Boston Dynamics has produced a number of robots that mimic human and animal movement, including Atlas, a humanoid model that co-ordinates motion and balance using its arms and legs and can pick itself up off the ground when knocked over.

Holiday Magic also includes singing to the animals, a model railroad display, photo opportunities with animals, professional ice - carving demonstrations and a 41 - foot talking tree.

Beyond diapers, you'll love the charming selection of totally affordable and Earth friendly fun stuff for your little one, including dump trucks, modeling clay, wooden animal figures, books, puzzles and more from manufacturers that share Earth Baby's philosophy.

Based on animal models, including a primate model, it is hypothesized that the cells remain unharmed in the digestive tract of the infant then enter the bloodstream, migrate to different organs, and there provide active immunity.54

Page and his colleagues, who use animal models to understand how autism risk factors impact the developing brain and to identify potential treatments for the condition, have found that animals with mutations in the autism risk gene phosphatase and tensin homolog (Pten) mimic aspects of autism, including increased brain size, social deficits and increased repetitive behavior.

Strategies that boost the cell's quality control programs, rather than disarm specific pathologic proteins, have looked promising in lab animals that serve as models for human neurodegenerative disorders including Alzheimer's, Parkinson's, Huntington's, amyotrophic lateral sclerosis (ALS) and frontotemporal dementia.

The journal provides cutting - edge research including results from animal models that are likely to apply to patients, studies in human tissue that provide new information about therapies or disease, and innovative reports of drug discovery and development.

The brochures contain information about toxicology, pharmacology, and animal safety studies used to determine the potential risk a particular therapy may pose to humans, but they also include efficacy studies done in animal models to demonstrate a therapy's potential benefit.

Its research includes a cluster of related interdisciplinary projects that examine disparities in breast cancer mortality between African - American and Caucasian women using animal models, molecular characterization of tumors, and behavioral research focused on social - environmental factors.

Ko is quick to note that these new findings do not warrant radical dietary changes in people with Crohn's: More studies, including more refined genetic analyses of fatty acids and Crohn's and testing in animal models, are needed.

«The next stage would be to repeat the study in primates, a more suitable animal model where HIV infection induces disease, in order to further demonstrate elimination of HIV - 1 DNA in latently infected T cells and other sanctuary sites for HIV - 1, including brain cells,» Dr. Khalili said.

The stem cell - derived beta cells are presently undergoing trials in animal models, including non-human primates, Melton said.

For the JCI study, the team applied the radiotracer to monitor olfactory sensory neuron population dynamics in a rodent model, using PET to measure its uptake across the animals» lifespan, including during age - related neurodegeneration.

This dosing also exceeded the predicted human efficacious dose for AVI - 7288 estimated by three different models based upon the nonhuman primate studies that demonstrated up to 100 percent animal survival, including a delayed time - to - treat setting.

A row of scientifically accurate models of Proboscidean heads runs along the wall in evolutionary order, including a small - trunked animal from about 25 million years ago, and the long - faced Gomphotherium, a close relative of the elephant and an ancestor of the woolly mammoth from about 5 million years ago.

He says research in animal models indicates that many, including uranium, lead and cadmium, are capable of inducing autoimmunity.

«For the first time, we can provide a complete description of an animal model from genes to behavior — including at the level of neuronal network activity, which has been ignored in most studies to date.»

It's not clear what would happen to the rest of NCRR's portfolio, which includes support for construction and instrumentation, primate centers and other model animal resources, and grants for minority institutions and states that don't have much NIH funding.

MERS and SARS: The pause includes three grants and two contracts that are attempting to develop a strain of the MERS coronavirus that sickens mice so that researchers will have an animal model for testing MERS drugs and vaccines.

The findings offer needed information in several arenas, Buckner said, including evidence that ravens could serve as animal models in research involving social cognition.

C.elegans has been used for decades as a model animal to study the genetic and molecular underpinnings of neurological disorders through a number of techniques including bio imaging, electrophysiology and behavior.

Many diseases can be detected at the surface of tissues, including cancer, while many pre-clinical studies are performed with animal models and engineered three - dimensional tissues that can benefit from being monitored non-destructively.

Way and his colleagues, including co-first authors Lucien Turner and Jeremy Kinder, PhD, stress that because study was in animal infection models, it's premature to say how the findings will apply clinically.

Brendan Wintle at the University of Melbourne, Australia, has developed an alternative model that includes data on previous searches in remote regions, as well as aspects of the animal's biology and behaviour.

The results, published in the current issue of Human Molecular Genetics, open the door for pursuing gene editing in nonhuman primates as models for new therapies, including pharmacological, gene - and stem cell - based therapies, said Keith Latham, MSU animal science professor and lead author of the study.

Researchers have pursued alternative therapies for TB using a variety of animal models, including the zebrafish found in many pet stores and household aquariums.

The new NIH project includes collaborators with expertise in animal modeling as well as device manufacturing.

We do studies to understand the exact relationship between genotype and phenotype in both animal models and in human subjects including twins.

These findings are promising for developing a preclinical, large animal model of Huntington's disease for assessing new therapeutics, which could ultimately provide better treatment options, including altering the course of the disease.

Access unique research animal models through Wake Forest Innovations, including a world - class nonhuman primate center and other large animal research models.

Included are talks on mechanisms of aging in a wide range of established and non-traditional animal models with the key objective to enhance understanding of the basic biology behind experimental and lifestyle manipulations thought to have direct translational application to human aging.

The team, including researchers from the Natural History Museum in London, quantified the anatomical and genetic differences between living animals, and established a timeframe over which those differences accumulated with the help of the fossil record and intricate mathematical models.

We are actively engaged in advancing novel methods to image molecular events in both humans and animal models that include receptor expression, proliferation, angiogenesis, and apoptosis.

Examples of funding areas include but are not limited to molecular genetic analysis of relevant neural circuit assembly and function; genetic and epigenetic research; animal models created by genetically altering neural circuits; and testing of new chemical entities that might be used in animal models as exploratory treatments.

Major areas of emphasis include regulation in genetically modified animals, the use of model organisms and comparative functional genomics.

Understanding cattle movement patterns as well as the connectivity of the various sectors of the U.S. cattle industry and incorporating these in the models would allow USDA Animal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including boviAnimal Plant Health Inspection Service (APHIS) Veterinary Services (VS) to develop more effective regulations and control strategies for various animal diseases, including bovianimal diseases, including bovine TB.

His major research interests are human neuroanatomy and neuropathology and the use of animal models to test novel therapies for neurodegenerative diseases including Alzheimer's disease.

Taking advantage of infected patients, proprietary animal models of infection and new technological advances in the field of static and dynamic imaging, Immunopathology Unit tackles unresolved issues that include the means by which innate and adaptive immune cells traffic and function within the normal, cirrhotic or cancerous livers.

We hope not only to discover how brains support decision - making in any animal, humans included, but also to offer a new large - scale, collaborative model for brain science.

Dr. Parsons has provided similar insights into the mechanisms through which endocannabinoids modulate the rewarding effects of opiates, alcohol, and cocaine, and he is presently extending his evaluations of this stage of the addiction cycle to include animal models of commonly occurring genetic polymorphisms that are associated with problematic drug use and dependence in humans.

Dr. Amaral's interests include research involving multidisciplinary studies directed at determining the neuroanatomical, behavioral and electrophysiological organization and functions of brain systems that are involved in learning, memory, emotion and social behavior carried out on the human brain and on animal models.

Martinez - Trujillo, a member of Western's renowned Brain and Mind Institute, notes that most spatial memory experiments include animal models being tested in actual, real - world mazes while humans are assessed virtually, using computer screens, more often than not in a two - dimensional setting.

Dean LaFerla has several research interests, including the molecular biology of Alzheimer's disease and other neurodegenerative disorders, presenilins and calcium signaling, learning and memory, and transgenic and genetically modified animal models.

Researchers have established a strong genetic component for addictive behaviors through studying animal models, including laboratory mice.

Preclinical diabetes models and islet transplantation in small and large animals (including non-human-primates)

Currently IDOBRU imports 66 Brucella vaccines from the Vaccine Ontology (VO; http://www.violinet.org/vaccineontology [21], including four licensed animal Brucella vaccines and 62 Brucella vaccine candidates that have been proven effective in laboratory animal models [33].

Model systems include organotypical slice cultures and transgene animals.

Depending on topics, I have been working on a variety of animal models, including flatworms, snails, crustaceans, fishes, amphibians, birds and mammals.