Sentences with phrase «animal models of diseases targeted»

Once this work is completed, a second stage is committed, in which researchers of I - Stem, in collaboration with specialists in animal models of diseases targeted by the therapeutic explore the effects of experimental transplantation of cells obtained laboratory.

Not exact matches

From accelerating the identification and validation of novel therapeutic targets, to creating better animal models of human diseases in a shorter time frame, to reducing the number of failed products, Crispr looks set to shave millions off R&D costs and boost drug discovery, she says.

Future work will focus on identifying cellular targets of ampulexins, and potentially generating a useful animal model for the study of Parkinson's disease treatments.

The CCFA Genetics Initiative seeks to deliver validated pathway models of IBD disease mechanisms, new animal models for analysis and development, chemical probes of relevant pathways, new proteins and pathway targets, recruitment of new IBD investigators, and a tested paradigm for rapid analysis and cure for Crohn's disease.

Biomedcode welcomes suggestions and proposals for the development of novel animal disease models as well as for the generation of animals humanized for targets of interest.

Scientific meeting «Gene targeting, genome editing & transgenesis: research application» We are organizing joint meeting with our colleagues from Masaryk University in Brno dedicated to current progress in transgenic technologies in research application, animal models of diseases and Wnt signalling.

Targets of research range from basic molecular and cellular mechanisms, the manipulation of these mechanisms in animal models, analyses of the genes and gene products in cardiovascular disease, and clinical research that seeks to improve diagnosis and therapy for patients.

• Disease - driving pathways that involve the human immune system are often targeted by antibodies, and Organ - Chips recreate complex interactions of different human cell types and aspects of the human immune system, overcoming limitations of animal models which do not reflect all human immune cells.

Moreover, knock in animal models for syngeneic studies and allowing us to isolate transgenic armed effector cells are developed in order to show proof of concept for the diverse applicability of our modular targeting systems including for tumor diseases, autoimmune diseases, GvHD, transplantation / rejection as well as viral infections.