Sentences with phrase «animal patients with»

As described above, there is compelling evidence that significant tissue - level cobalamin deficiency is present in some companion animal patients with gastrointestinal disease.

RT @AuburnVetMed: The Cardiology service provides specialized diagnosis and care of small and large animal patients with heart problems.

The Soft Tissue and Oncologic Surgery service cares for small animal patients with a variety of «soft - tissue» diseases and conditions.

It is probably not rare to have a need of anesthetizing small animal patients with common endocrine diseases, such as diabetes mellitus, hyperthyroidism and hypoadrenocorticism.

I use it everyday to treat my children, pets and husband, not to mention on at my veterinary clinic for my animal patients with trauma, post surgical or chronic pain.

Led by four surgeons — Mathews, Scharf, Christopher Adin and Marije Risselada — the soft tissue and oncologic surgery service sees small animal patients with a wide variety of conditions.

Not exact matches

By printing multiple lung airways — or any other afflicted organ — from a human patient and testing drugs on them, pharma companies can bypass the ethically challenged practice of testing on animals and proceed to human clinical trials with greater confidence the drugs will actually work, according to Wadsworth.

This is done routinely in experiments with animals and occasionally with human patients undergoing neurological treatment.

Although more and more human studies are being conducted to validate claims found in animals, many studies are with patients with a certain illness or condition (ex.

BURNET, Texas (June 12)-- It is popular and expedient in politics to champion taxpayer rights, state's rights, patient rights, gay rights, people - with - disabilities rights, even animal rights.

«There was no history of travel or contact with animal by the said patient.

To better understand their findings, the team examined the animal model for APS1 (i.e. mice with the same genetic defect as human patients with the syndrome) and found that male mice spontaneously developed an inflammatory disease in their prostate glands — a so - called prostatitis — and reacted to transglutaminase 4.

Oliver sent his postdoctoral student Tom Kollars to trap animals, including wild rabbits, at a farm where two of Masters» patients had developed EM rashes along with arthritis, muscle aches and other Lyme - like symptoms after lone star tick bites.

With that approach, informed by prior research in animals, the research team ultimately identified four proteins (copeptin, galectin 3, matrix metalloproteinase 9 and occludin) that changed dramatically in the bloodstream of patients shortly after they had a concussion.

Further studies in animal models and patients (with altered TRPM7 channel function) have been initiated, in order to evaluate the efficacy and safety of magnesium as a therapeutic for this disease.

Previous research has looked at animals or patients with more prolonged cardiac arrest.

Although the Harvard criteria were based on zero patients and no experiments were conducted either with humans or animals, they soon became the standard for declaring people dead in several states, and in 1981, the Uniform Determination of Death Act (UDDA) was sanctioned by the National Conference of Commissioners on Uniform State Laws.

Researchers performed a meta - analysis of literature examining patients with NASH, and then tested their hypothesis using an animal model, which enabled them to eliminate possible confounders of the clinical data, such as antibiotic exposure and medical comorbidities.

McDonald is working with medicinal chemists at Vanderbilt to develop more selective and potent PGD inhibitors for testing in animal models, with the ultimate goal of moving these inhibitors into clinical trials for pancreatic cancer patients.

Because the researchers found that CTLA4Ig was effective in suppressing hepatitis in this study, they suggest that CTLA4Ig should be among the therapeutic options investigated further as a potential therapy for patients with severe acute hepatitis B. To this end, this animal model is useful for virological and immunological analysis of HBV infection.

A total of 145 patients has been diagnosed in recent weeks with a strain of the H3N2 animal influenza virus, but it likely has not yet evolved the ability to transmit efficiently between humans

They found that, within the first three days of injury, fish in the concussion group were slower to find a school of fish with which they previously swam, a measure of spatial memory which is impaired in other animal models of concussion and human patients.

This anxious behavior mirrored that of CdLS patients, while autopsied brain tissue from individuals with CdLS showed symptoms of disease that matched those of the experimental mice suggesting that they were a good animal model.

The researchers hope these findings will aid in developing new treatments by using animal models that more closely represent the types of mutations apparent in the vast majority of patients with enchrondromas.

Animal studies have suggested that overactivation of TLR7 plays a role in lupus, and a gene variant that increases expression of the receptor has been associated with increased lupus risk in human patients.

Both groups of animals were equivalent to 55 - to 60 - year - old morbidly obese patients with uncontrolled diabetes, the most difficult population to treat.

Importantly, these devices also will open up new approaches to drug development not possible with animal models today, such as personalized medicines and development of therapeutics for specific genetic subpopulations using chips created using cells from particular patients.»

Prototypes could detect carcinoembryonic antigen, a protein present in high levels in patients with colon or rectal cancer; ractopamine, which is an animal - feed additive banned in many countries; and thrombin, a cardiovascular disease marker.

The results of these animal trials may eventually help patients with colon, rectum, stomach, breast, or lung cancer.

Sumitran - Holgersson says she hopes in future to try using blood vessels from animals for re-coating with patients» own cells, as the source would be potentially limitless.

The researchers studied the adhesion mechanisms using detailed biochemical analyses and state - of - the - art genetic systems, combined with unique H. pylori clinical strains and biopsy - materials collected from individual patients and animals over a span of many years.

Yet despite achieving some encouraging results in animal models of MS, drugs that block the activity of TNF tend not work in patients with MS.. In fact, they usually make symptoms worse, and they may even have caused the disease in people predisposed to it, says Fugger.

However, data from animal studies of Ebola, as well as studies of patients with infectious diseases such as tuberculosis, provide a sound basis for initial recommendations.

The study looked at a way to substitute animal - based saturated fats for plant - based unsaturated fats in muffins made for patients with the metabolic syndrome, a group of risk factors that affect about a third of adults in the United States, increasing their chance of cardiovascular disease and type 2 diabetes.

At the asylum and the army barracks, he and his team also infected patients with infectious syphilis bacteria taken from humans and animals, mixed with beef heart broth, distilled water, or spinal fluid.

In their research, scientists at Rutgers created animal models that closely resemble the cancerous tumors found in women with ovarian cancer by injecting tumor tissues obtained from gynecological cancer patients treated at the Cancer Institute into laboratory mice.

Further research based on autopsy specimens and animal experiments will be needed to clarify the relationship and determine if the patients with MRI hyperintensity in their brains have symptoms.

And in 1923, one patient developed a serious heart infection, like some young animals with the disease.

«This is the first time researchers have been able to successfully mimic in any animal the progressive hearing loss observed in USH3 patients with a disabling mutation in the clarin - 1 gene.»

As a next step, they plan to test the probe in animal models and with patients in a clinical setting.

With a possible government shutdown only a few days away, the National Institutes of Health (NIH) appears to be ready to send in a skeleton staff to care for patients and maintain animals and experiments at the agency's Bethesda, Maryland, campus.

In addition to the animal model, the scientists also studied 33 patients with neurodermatitis and found that they have increased quantities of MDSCs in their blood and on their skin in comparison to healthy individuals.

Scientists seeking to understand the neural mechanisms underlying social cognition and emotion have drawn on a variety of methods, including studies of patients with neurological damage and single - cell recording of brain activity in nonhuman animals.

Efforts to improve patient outcomes, particularly for those with high - risk Group 4 medulloblastoma, have been hampered by the lack of accurate animal models.

Future studies should investigate whether, or how, the genetic alterations that lead to this ASD animal model change the serotonin system, with the aim to provide possible insight into serotonergic deficits in human patients, the authors say.

Cleveland Clinic researcher Nima Sharifi, M.D., found that abiraterone, a steroid inhibitor, is converted into the more physiologically active D4A (Δ4 - abiraterone) in both patients and animal models with prostate cancer who take the drug.

To investigate whether induction of IAPP aggregation leads to some of the clinical alterations typically observed in patients with T2D, we measured fasting blood glucose at different times after inoculation in the same animals used for IAPP histological analysis shown above.

«By using an animal model to expand tumor cells recently removed from patients, we hoped to re-create more closely what actually happens in patients with pancreatic cancer rather than by using existing artificial cell lines,» said Wei Zhang, Ph.D., an endowed Hanes and Willis Family Professor in cancer at Wake Forest School of Medicine, a part of Wake Forest Baptist, and principal investigator of the study.

Interestingly, high expression of KLF4 was significantly and inversely correlated to brain but not bone metastasis - free survival of patients with breast cancer, and we indeed found that the expression of miR - 7 significantly suppressed the ability of CSCs to metastasize to brain but not to bone in our animal model.

The changes in locomotor activity are associated with fluctuations of anxiety - like and depression - like behaviors, suggesting that the mutant mice may serve as an animal model showing infradian oscillations of mood substantially similar to those found in patients with bipolar disorder.