(G, H) gbp1, gbp2 ex67 mutant
animals show reduced body size both in females (G) and males (H).
As we expected,
these animals showed reduced body size (Fig 2G — 2J), slower growth rate (Fig 2K), and extended duration of the L3 (Fig 2L).
When we knocked down GBP1 and GBP2, either alone or in combination, using ppl Gal4, the resulting
animals showed reduced body size, reduced growth rate, and extended growth duration.
Not exact matches
This natural sweetener has also
shown great promise in
animal studies for
reducing weight gain and body fat when substituted for sugar.
In
animal studies, activation of nuclear factor - kappa B (NF - kB); activation of inducible nitric oxide synthase (iNOS), and cyclooxygenase - 2 (COX - 2); and formation of malondialdehyde (MDA) have all be
shown to get
reduced following consumption of either sweet potato or its color - containing extracts.
For example, studies have
shown the tannins contained in certain sorghums
reduces caloric availability and thereby weight gain in
animals.
Studies have
shown that spending time with
animals can
reduce stress and anxiety levels!
The results, published in Nutrition Research in 1988,
showed reduced tumor growth rates in
animals receiving phytic acid, but not in a control group.
These results
show the potential of alternative strategies of
animal feeding to
reduce the environmental issues associated with agriculture.
When polar bears» feeding opportunities decrease during the summer ice melt, the
animals can
reduce their energy expenditure a little, but not enough to make up for the food shortages, a study in the 17 July issue of Science
shows.
Of course, if the bloom is eaten, then
animal metabolism will reemit the CO2, sending it back to the atmosphere and defeating the purpose of
reducing CO2 emissions, as prior scientific studies have
shown.
«To kill ticks, target their
animal hosts: Luring mice, chipmunks to contact insecticide
shown to
reduce nearby tick presence.»
A new study
shows that at least two diatom species make compounds that
reduce hatching rates when eaten by tiny shrimplike
animals called copepods.
The results
showed that sleeping on
animal skin was associated with a
reduced risk of a number of factors connected to asthma.
These
animals showed signs of depression, including
reduced levels of the hormone serotonin, which is a hallmark of the condition.
For the
animal study, the researchers separated 52 mice with colon cancer tumors into three groups, including a control group and groups that were fed either the grape compounds or sulindac, an anti-inflammatory drug, which was chosen because a previous study
showed it significantly
reduced the number of tumors in humans.
Reducing this gut - associated inflammation has been a goal of clinicians and researchers, and rebalancing the gut microbiome has
shown promise in small -
animal studies.
He describes work that
shows that dietary deficiency of alpha - linolenic acid (a fatty acid found in rapeseed oil)
reduces the learning capacity of experimental
animals.
For years, people have attributed runner's highs to endorphins, but when researchers blocked the effects of these hormones in running mice, the
animals still
showed signs of runner's high —
reduced anxiety and less sensitivity to pain.
Animal models and clinical trials have
shown that antioxidants and anti-inflammatory drugs could not only
reduce symptoms associated with the disorders but also prevent the appearance of neurobiological abnormalities and transition to psychosis if given early during brain development.
The reason, according to the research published in the journal Human Reproduction (pdf): soy beans contain high amounts of phytoestrogens, organic compounds that mimic the female hormone estrogen in the human body and, in
animal studies, have been
shown to
reduce testosterone levels.
A new study in
animals shows that using a compound to block the body's immune response greatly
reduces disability after a stroke.
The results
showed that at high speed, the
animals reduce the degree to which their legs move in a synchronized manner.
In the converse experiment, the group
showed that when increasing lipid production in lungs of
animals already injured and developing pulmonary fibrosis, lung scarring could be
reduced by 70 - 80 percent.
The new study
shows deleting Rhes significantly
reduces behavioral problems in
animal models of the disease.
«With this novel
animal model, we
showed how it enhances fear rather than
reducing it and where the molecular changes are occurring in our central nervous system.»
A second experiment
showed that the drugs - plus - DNA therapy
reduced bacterial growth from a secondary infection, and in one of seven
animals, it gave «complete protection» to the lungs against reinfection.
For example, studies have
shown that young, inactive rats have
reduced insulin sensitivity (a precursor to type - 2 diabetes), eat more and burn off fewer calories, and develop larger fat pads than
animals who continue to exercise.
According to the results, two compounds similar to progesterone
showed an equivalent ability to
reduce brain swelling in an
animal model of traumatic brain injury.
We do this because
reducing variability means that we will have greater power in our statistics to
show phenotypic differences and ultimately be able to use fewer
animals.
Psychological stress and glucorticoids have been
shown to increase FOXO3 in
animal studies, 36, 37, 38 whereas low levels of FOXO3 in mice actually prevent the behavioral stress response in mice, serving an antidepressant effect.39 We believe our study is the first documentation that a stress reduction intervention can
reduce FOXO3 expression.
He also has
shown that
reducing tau levels, or suppressing the abnormal excitability of these networks with drugs, can both
reduce cognitive and behavioral deficits in
animal models of Alzheimer's disease.
The survey also
showed that the application of biostatistical methods is an effective way to both Refine and
Reduce the number of
animals used.
By the end of that year, they had
shown in classic
animal experiments that pancreatic extracts
reduced blood sugar, removing sugar from the urine of dogs whose pancreas had been removedANCHOR.
In some cases affected transcripts in Cre +; Tsc1 flox / flox mice
showed significant variation among individuals that can not simply be explained by differential effectiveness of CRE - mediated knockout since, except one
animal, all Cre +; Tsc1 flox / flox mice
showed similarly
reduced expression levels of Tsc1 mRNA.
Previous studies have
shown that agents that block the NMDA receptor
reduce depression - like behaviors in
animals.
Animal studies have
shown that these antioxidants can promote healthy liver and kidney function, and
reduce diabetic complications.
While no formal studies have proved that cinnamon and honey can successfully treat the symptoms of rheumatoid arthritis in humans so far, studies performed on
animals have
shown that these two ingredients can significantly
reduce inflammation and relieve arthritic pain.
Both
animal and laboratory studies
show that vitamin D protects neurons from the damaging effects of free radicals and can
reduce inflammation — all good things in terms of skin health.
Pineapple juice has also been
shown to help
reduce inflammation of the digestive tract in
animal studies.
Animal and human studies about caloric restriction
show that when calories are
reduced by 30 - 40 %, the subjects tended to live a lot longer — 30 % longer actually.
[4] One study
showed that a higher consumption of
animal protein over a period of 5 years was associated with a significantly
reduced risk of gaining belly fat.
Studies have
shown that a diet low in
animal products or devoid of
animal products is the most effective way to
reduce your LDL cholesterol level (5,32 — 34).
They chose to study a plant - based diet because of ample evidence
showing that
reducing animal product intake (high in nutrients known to promote insulin resistance, including fat, protein, and heme iron) can not only improve diabetes health, but reverse diabetes altogether (8 — 14).
In another portion of the study,
animals that received a single 20 milligram per kilogram body weight dose of cilantro seed extract
showed reduced blood sugar levels 6 hours after the dose, but no change in cholesterol levels.
They have been
shown to decrease the risk of heart disease in
animal studies by
reducing inflammation in the arteries (47).
The calming effect reaches as far as the bone marrow and lungs, where, as a recent Nature Medicine study
showed, the acids
reduced animals» vulnerability to asthma.
Human and
animal studies has
shown HCA helps lower levels of triglycerides in the blood,
reducing the oxidative stress throughout the body.
CoQ10 administration has been
shown to
reduce production of ROS by mitochondria exposed to Aβ in
animal models of diabetes.18 With the AD brain struggling to produce energy and under great oxidative stress, CoQ10 could be a powerful adjunct.
(55) A 2007
animal study with primates treated with either bioidentical progesterone or a progestin (Provera ™)
showed that the progestin drug (Provera ™) worsens breast cancer biomarkers, while the bioidentical progesterone provides a beneficial effect on breast tissue and
reduces cancer markers.