In addition to genomic sequencing, the BDGP is 1) producing gene disruptions using P element - mediated mutagenesis on a scale unprecedented in metazoans; 2) characterizing the sequence and expression of cDNAs; and 3) developing informatics tools that support the experimental process, identify features of DNA sequence, and allow us to present up - to - date information about
the annotated sequence to the research community.
This webcast will cover how Horizon Discovery has used the recently released
annotated sequence...
We will be able to include the identification of these genes on
the annotated sequence when it is published.
Then the researchers began the process of correcting and
annotating the sequence.
This sequencing centre plans on publishing the completed and
annotated sequences in a peer - reviewed journal as soon as possible.
Not exact matches
Dr Nicholas Casewell said: «These are the first snake genomes to be
sequenced and fully
annotated and our results in relation to the king cobra provide a unique view of the origin and evolution of snake venom, including revealing multiple genome - level adaptive responses to natural selection in this complex biological weapon system.
I eventually became leader of Annotation Software R&D — the group that wrote much of the software used to
annotate and analyze the various genomes
sequenced at Celera.
This is the most complete and accurate bread wheat genome assembly to date with 91 per cent (98,974 genes) of the total genome
annotated and assembled — a total
sequence length of 13.4 GB.
Students in the program learn to isolate and characterize bacteriophages,
annotate the phage genomes, and then submit the
sequences to a national database.
The genomes of these 377 bacterial isolates, plus an additional 107 single bacterial cells from roots of A. thaliana, were then
sequenced, assembled, and
annotated at the JGI.
The previous record holder for genomic 6mA, noted Mondo, is the alga Chlamydomonas reinhardtii (
sequenced and
annotated by the DOE JGI), in which just 0.4 % of adenines were methylated.
The yellow - flag system would consist of a centralized biosafety
sequence database that would be
annotated as evidence of the function of suspect genes comes to light.
Biologist Leonore Reiser, curator for The Arabidopsis Information Resource (TAIR), says some groups train undergrads to handle some of the more routine curating tasks, such as triaging the papers to be included in the database or
annotating the features in a DNA
sequence.
The DOE JGI team first
sequenced, assembled and
annotated the 26.2 - million base genome of E. rubrum.
For now, the public and private teams are planning to produce independent scientific papers on the
sequence data and, after that, to
annotate the data independently.
The size and complexity of their genomes (∼ 20 — 40 Gb, 2n = 24) have delayed the arrival of a well -
annotated reference
sequence.
The
annotated, whole - genome
sequence of TMAdV has been submitted to GenBank (accession number HQ913600).
By deeply
sequencing nuclear RNAs and applying the computational tool StringTie to assemble transcripts, the researchers were able to
annotate 69 % of human miRNAs and 75 % of mouse miRNAs.
Three oil palm genomes, the dura and pisifera fruit forms of E. guineensis, and E. oleifera were
sequenced, assembled and
annotated.
Multiple
annotated DNA
sequences, DNA design and assembly files, primers, plasmids and strains have been produced, validated, and shared.
-- In silico basic and systems biology: We develop innovative approaches to reverse engineer biological networks from omics data, model tumor progression at the genomic, transcriptomic and epigenetic level, automatically
annotate new proteins and functional elements through integration of complex and heterogeneous data, including data obtained from high - throughput
sequencing or time - lapse video - microscopy.
The goals of the project are as follows: (1) to shotgun
sequence the C. murisgenome to 8X coverage; (2) to
sequence 20,000 clones from a C. muris cDNA library to provide gene prediction training and verification data; and (3) to manually
annotate the C. muris genome
sequence in comparison with the genome
sequence data for C. parvum and C. hominis.
A protein database was constructed in a FASTA format using the
annotated bacterial and viral proteome
sequences derived from all fully
sequenced chromosomes of bacteria and viruses, including their
sequenced plasmids (as of September 2008)[16], [17].
In addition to
sequencing a few more passenger pigeon genomes (which will be useful to evaluate how genetically diverse they were), we are assembling and
annotating the genome of the band - tailed pigeon.
In a study published ahead the week of January 8, 2018 in the Proceedings of the National Academy of Sciences, a team led by researchers at the Technical University of Denmark (DTU), the DOE Joint Genome Institute (JGI), a DOE Office of Science User Facility, and the DOE's Joint BioEnergy Institute (JBEI), led by Lawrence Berkeley National Laboratory (Berkeley Lab), report the first results of a long - term plan to
sequence,
annotate and analyze the genomes of 300 Aspergillus fungi.
An in vivo - vitro shuttle system for the study of P. cynomolgi liver stages12 is being exploited to better understand hypnozoite biology using molecular tools and genome - scale approaches, which rely on the availability of a complete and well
annotated P. cynomolgi reference genome
sequence.
This application uses calculated break points to determine fusion genes based on the latest annotation for genomic
sequence information, and where relevant the structural variation (SV) events are
annotated with predicted RNA and protein
sequences.
Input a DNA
sequence of up to 150,000 nucleotides to identify the genes and transposons in it, and
annotate (associate) the
sequence with this information.
When we compare the complete gene models we have reconstructed with those currently
annotated, both the amount of the receptor transcript
sequence, and the proportion that is unique between receptors increases substantially.
Ensembl genes that match VR cDNA
sequences but are
annotated as «novel genes».
List of VR and OR genes that have introns within the
annotated coding
sequence.
OR and V1R genes typically have coding regions that span a single exon, but we identified 54 OR and 15 V1R genes where at least one of the reconstructed transcripts has an intron within the protein coding
sequence (as
annotated in Ensembl).
Accordingly most only have their protein coding
sequences annotated in genomes.
He played a vital role in
annotating the genome
sequences of human, mouse, chicken and several other organisms; this work has had a profound impact on our understanding of genomic biology.
We recovered 35 Ensembl genes that were not
annotated as a VR gene, but that perfectly matched a VR cDNA
sequence.
All
sequence reads were aligned to (1) plasmid
sequences available in the NCBI RefSeq database (2138
sequences) and (2)
sequences in GenBank nucleotide database
annotated as plasmids (\ organism feature = «plasmid»)(9815
sequences).
A system for automated detection of homologs among the
annotated genes of several completely
sequenced eukaryotic genomes.
While whole genome
sequencing studies have failed to identify coding mutations in 40 % of the cases, there is evidence from recent efforts to
annotate the non-coding
sequence that over 80 % of the genome is biochemically active.
A read was
annotated as a resistance gene according to its best BLAST hit (blastx or tblastx) if (1) the hit had an amino acid
sequence similarity above a given threshold and (2) if the alignment was at least 25 amino acids.
For each slice digital RNA
sequencing was performed providing expression levels for the entire transcriptome,
annotated with the head - to - tail coordinates of the slice: a protocol they call «tomo - seq».
A read was
annotated as an insertion
sequence according to the best BLAST hit if (1) the hit had a
sequence similarity above 80 % and (2) if the alignment was at least 50 bases.
Reads with a significant hit to the qnr PSSM and that aligned with at least 25 amino acids with 90 %
sequence similarity to a known qnr gene were
annotated as known.
To
annotate the genome, the team generated transcriptome
sequence data — which can be used to measure gene expression based on RNA levels — in 12 different tissues types.
--
Annotated Coffee Run Rehearsal — Day one of production involved one of the film's most elaborately choreographed
sequences where every movement is carefully crafted.
The product is a binder containing an
annotated scope and
sequence for each grade level or course.
In a year - long research project, the school students will work alongside scientists to produce the first fully
annotated (labelled) genome
sequence for the human whipworm.
This is their first major exhibition in the States, and will feature film still
sequences, and videos and
annotated scripts.
The blinking slide
sequence includes images drawn from Leavitt's original
annotated photographic plates of variable stars, archival images from the «Human Computers» workplace, and a series of over 20 images of craters on the moon named after women astronomers.
The goal of the team's research was to demonstrate the value of the genomic
sequencing and comparison of mammals as a tool for
annotating the human genome and the efficiency of a particular
sequencing technique.