Actual results
and the timing of events could differ materially from those anticipated in the forward - looking statements due to these risks
and uncertainties as well as other factors, which include, without limitation: the uncertain timing of,
and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety
and efficacy in clinical testing; Alder's ability to conduct clinical trials
and studies of eptinezumab sufficient to achieve a positive completion; the availability of data at the expected times; the clinical, therapeutic
and commercial value of eptinezumab; risks
and uncertainties related to regulatory
application, review
and approval processes
and Alder's compliance with applicable legal
and regulatory requirements; risks
and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain
and protect intellectual property rights,
and operate without infringing on the intellectual property rights of others; the uncertain timing
and level of expenses associated with Alder's development
and commercialization activities; the sufficiency of Alder's capital
and other resources; market competition; changes in economic
and business conditions;
and other factors discussed under the caption «Risk Factors» in Alder's
Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities
and Exchange Commission (SEC) on February 26, 2018,
and is available on the SEC's website at www.sec.gov.
«Precision medicine is already positively affecting providers (for example, by reducing ED visits by 30 % through
application of molecular profiling treatment strategy); payers ($ 25 billion expected
annual spending on genetic tests by 2021,
and 45 % of FDA
approvals were geared toward targeted therapies in 2013);
and pharma (the pharmacogenomics market is expected to be $ 7.5 billion by 2017).»
By capping the number of charter schools statewide, limiting the
annual growth in the number of schools per district,
and providing for input from the local district before
approval of charter
applications, North Carolina has exercised more control over the establishment of charter schools than some states.