But today, the bacterium Bacillus anthracis that causes
the anthrax disease has become a weapon in bioterrorism.
Not exact matches
Researchers could now see the culprits and distinguish between similar
diseases such as
anthrax, cholera and, yes, bubonic plague, which was isolated in 1894 and named Yersinia pestis in honor of Swiss microbiologist Alexandre Yersin.
Although much of that money goes to stockpiling vaccines and improving
disease surveillance and information exchange, part of it pays for research into improved vaccines and other «countermeasures» against smallpox,
anthrax, and botulinum toxin.
Due to this severity, the CDC has made tularemia a reportable
disease, and like the pathogens causing
anthrax and plague, it is considered a bioweapon.
«Secondly it shows that this was, would be a viable route for the spread of those other infectious
diseases like Bubonic plague and leprosy and
anthrax that people had previously suggested might have been spread between East Asia and Europe along the Silk Road.
Ames is more likely than other strains of
anthrax to cause
disease in animals immunised with the standard US
anthrax vaccine, which is now being given to US troops.
Hunting and deforestation have already brought chimpanzees to the brink of extinction, but «
diseases such as
anthrax, Ebola, or introduced human respiratory viruses may serve as the final nail in their coffin,» says
disease ecologist Tom Gillespie of Emory University in Atlanta.
The first, called bio-bar-code assays, relies on nanoparticles designed to attach themselves to specific
disease - causing proteins; these will vastly improve a doctor's ability to detect
diseases like cancer and Alzheimer's in their early stages and to identify pathogens like
anthrax.
Overhyped microbes include
anthrax (famous for the U.S. mail attacks in 2000), the Ebola and Marburg viruses (which can cause dramatic bleeding and high fever in their victims), and the prion agent of mad cow
disease (otherwise known as bovine spongiform encephalopathy, or BSE), which kills people by making their nervous systems degenerate.
1850s German microbiologist Robert Koch connects a bacterium to a specific
disease — bacillus anthracis to the outbreak of
anthrax in cattle — and figures out how to grow bacteria in agar cultures in a lab.
«Recent reports of lapses in biosafety practices involving Federal laboratories» — the mistaken shipment of live
anthrax samples by a lab at the Centers for
Disease Control and Prevention (CDC) in Atlanta; the accidental contamination of benign poultry flu samples with the deadly H5N1 bird flu at the CDC; and the discovery of old vials of smallpox on the NIH campus in Maryland — «have served to remind us of the importance of constant vigilance over our implementation of biosafety standards,» the notice states.
The incidents included inadvertent shipments of live
anthrax samples at the Centers for
Disease Control and Prevention (CDC) in Atlanta and the Department of Defense, and the discovery of old vials of live smallpox on the campus of the National Institutes of Health.
«In principle, one could save people suffering from cutaneous late - stage
anthrax infections and maybe treat a variety of other similar
diseases,» said Bier.
We have vaccines now for
anthrax and antibiotics for
anthrax, and we have some stockpiles and a lot of other preparations for foot - and - mouth
disease.»
The U.S. Government monitors over 100 animal
diseases, including
anthrax and rabies.
But a serendipitous discovery may someday give doctors a new countermeasure against the
disease: Researchers report in tomorrow's Science that they have identified a possible mechanism of action for «lethal factor» (LF), a toxic protein produced by the
anthrax bacillus that is thought to be one of the principal causes of death in infected individuals.
Like
anthrax, diphtheria and botulism, C. diff infection is a toxin - mediated
disease.
In July, nearly two dozen government laboratories were locked down after more than 80 employees at the Centers for
Disease Control and Prevention in Atlanta were potentially exposed to live
anthrax bacteria.
Fascinated by emerging
diseases, he covered outbreaks on four continents, including the 2001
anthrax letters, the global outbreak of SARS in 2003, and the 2009 H1N1 influenza pandemic.
Last week, Tom Frieden, director of the U.S. Centers for
Disease Control and Prevention, held an unusual press conference to discuss three separate, recent mistakes involving lab safety with smallpox, influenza, and
anthrax.
Related sites Timothy Read's home page ScienceNOW story about TIGR's plan to sequence additional strains of
anthrax Anthrax information from the Centers for
Disease Control and Prevention
The category would include
anthrax, Ebola, Variola major and Variola minor (the two viruses that cause small pox), the Marburg virus, the virus that causes foot and mouth
disease, and bacterial strains that produce the botulinum neurotoxin.
Related sites Bali Pulendran's laboratory Web site at the Emory Vaccine Center The Centers for
Disease Control and Prevention's
anthrax Web site
Moreover, he believes that investment in technologies such as chip - based methods to rapidly test blood or tissue samples for the presence of
anthrax or smallpox would speed the development of related diagnostic tools for regular
diseases.
Following the suicide, the FBI released court documents laying out some of the evidence linking the
anthrax spores found in the letters to Ivins's lab at the U.S. Army Medical Institute for Infectious
Disease at Fort Detrick, Maryland.
In the future, they speculate, specific drugs to block LT may help
anthrax patients better fight the
disease.
Over the past decade, SNPs have shed new light on the genetic risk factors for common illnesses such as diabetes and heart
disease — and they've even helped federal investigators hone in on a suspect in the
anthrax case (ScienceNOW, 12 August).
MMF is the brainchild of Steve Bellan, an ecologist at the University of California, Berkeley, who specializes in the epidemiology of wildlife
diseases like
anthrax, and Juliet Pulliam of the University of Florida, Gainesville.
There's no debating that invading Europeans did introduce
diseases that decimated Native American peoples, but
anthrax probably wasn't one of them
False Alarm: The Truth About the Epidemic of Fear Marc Siegel; Wiley, $ 24.95 SARS,
anthrax, and mad cow
disease have in the past decade sickened and killed only a tiny minority of humanity.
We carry out translational research programmes to develop infectious
disease vaccines, therapeutics and diagnostics using animal models of tuberculosis, influenza, HIV / AIDS, Clostridium difficile, meningococcal
disease, chlamydia, burkholderia and
anthrax, as well as emerging viral
diseases such as Crimean Congo haemorrhagic fever.
These include MERS, Ebola,
anthrax, bubonic plague, and mad cow
disease.
According to Piers Millett, a specialist in anti-animal biowarfare from the Department of Peace Studies at Bradford University, the main targets for terrorists are likely to be rinderpest,
anthrax, foot and mouth, swine fever and Newcastle
disease, which affects poultry.
Ryan has worked in a wide range of
disease fields including cancer, HIV, tuberculosis, leishmaniasis,
anthrax, West Nile virus, leprosy, hookworm
disease, schistosomiasis, chikungunya virus, and shigellosis.
Bacillus anthracis is a Gram - positive bacterium that is the causative agent of
anthrax, a rare and deadly
disease that can infect the host by pulmonary, gastrointestinal (GI) or cutaneous routes [1, 2].
Trauma surgeon Grace Samuels is deployed to Afghanistan, helping soldiers overcome
disease and combat injuries... But a deadly outbreak of
anthrax is killing the people she cares most about Deadly Strain (Biological Response Team) by Julie Rowe
They delivered preventive health services including vaccines for rabies, Newcastle
Disease, hog cholera and
anthrax.
«The
anthrax vaccination is reliable and proven to protect livestock from the
disease,» said Dr. Andy Schwartz, TAHC Interim Executive Director.
People who live in areas where
anthrax has occurred should consider vaccinating their livestock against the
disease.
But already last year, a boy was killed and 20 others infected by
anthrax released when retreating permafrost exposed the frozen carcass of a reindeer killed by the bacteria at least 75 years earlier; 2,000 present - day reindeer were infected, too, carrying and spreading the
disease beyond the tundra.