An assessment of the risks associated with the use of
antibiotic resistance genes in genetically modified plants: report of the Working Party of the British Society for Antimicrobial Chemotherapy.
As well as Zika virus, the team has also used SHERLOCK to
detect antibiotic resistance genes in Klebsiella pneumoniae bacteria, and health - related gene variants in human saliva.
The largest metagenomic search
for antibiotic resistance genes in the DNA sequences of microbial communities from around the globe has found that bacteria carrying those vexing genes turn up everywhere in nature that scientists look for them.
The method is so effective in so many kinds of plants that «all previous technology
uses antibiotic resistance genes,» says Michael Syvanen, a microbiologist at the University of California, Davis.
The researchers, including Nesme and senior author of the study Pascal Simonet, took advantage of the ever - growing reams of existing next - generation sequencing data that are freely available in public repositories together with information
about antibiotic resistance genes found in pathogens infecting patients in the clinic.
Temporal succession of
soil antibiotic resistance genes following application of swine, cattle and poultry manures spiked with or without antibiotics — Yu - Jing Zhang — Environmental Pollution
Though the results of the experiment allowed Abate's lab to distinguish individual microbial species,
identify antibiotic resistance genes, and find virulence factors, he sees substantial room for improvement.
«The fact that we were able to detect
antibiotic resistance genes at relatively important abundance in every environment tested is certainly our most striking result.»
Now, research conducted at The Novo Nordisk Foundation Center for Biosustainability — DTU Biosustain — at Technical University of Denmark for the very first time shows that
antibiotic resistance genes originate from the same place as the antibiotic compounds, i.e. from a group of soil bacteria called Actinobacteria.
Reetta Satokari's group has an interesting ongoing project where they look at the effects of faecal microbiota transplant
on antibiotic resistance genes detected in the patient's microbiota.
They first suspected this when they noted that the bug has repeated sequences that look like those in known integrons, and the sequences flank not
only antibiotic resistance genes, but also genes coding for several other proteins, including some that are toxic.
While antibiotic resistance genes are not harmful in themselves, they limit the use of antibiotics for treating bacterial infections and pose a serious threat to global public health if they get transmitted to humans from environmental sources, such as compost.
Dr Friman said: «Developing safer ways to manufacture organic fertilisers can reduce our dependence of traditional chemical fertilisers, whilst at the same time ensuring that they do not impact on human health by
enriching antibiotic resistance genes in agricultural environments.»
Background Multidrug resistance (MDR)- encoding plasmids are considered major molecular vehicles responsible for transmission of
antibiotic resistance genes among bacteria of the same or different s...
Wastewater treatment plants (WWTPs) functioned as the intersection between the human society and nature environment, are receiving increasingly more attention on risk assessment of the acquisition of
environmental antibiotic resistance genes (ARGs) by pathogenetic populations during treatment.
The study, led by Moran Yassour, a postdoctoral fellow at the Broad Institute and Harvard Medical School in Boston, also found a temporary rise in the number of
antibiotic resistance genes when antibiotics were given.
More than three fourths of all current antibiotics used to treat human infections are produced by Actinobacteria, which at the same time
carry antibiotic resistance genes.
«Heretofore, C. sakazakii - contaminated infant formula has been considered an unsolved problem because antibiotics can not be used,» said Ryu, adding that C. sakazakii has been known to have
multiple antibiotic resistance genes.
Now, a team led by microbiologist Tim Kunkel of The Rockefeller University in New York City has shown that at least two crops — lettuce and tobacco — can be engineered without
using antibiotic resistance genes.
We look
for antibiotic resistance genes, both phenotype and genotype of the microbiotia and looking through the genetic signatures of antibiotic resistance.
Specifically, they have found unnaturally high levels of
antibiotic resistance genes in sediments where the river comes into contact with treated municipal wastewater effluent and farm irrigation runoff as it flows 126 miles from Rocky Mountain National Park through Fort Collins and across Colorado's eastern plain, home to some of the country's most densely packed livestock operations.
And on the subject of public health, it is worth exploding the number one myth of anti-GM lobbyists that
the antibiotic resistance genes carried by some GM crops might lead to devastating human epidemics if transferred to bacteria.