Not exact matches
They prepared a similar weapon
against liver
cancer by piggybacking rhenium 18 on
antibodies that target HBx, a viral antigen made by cancerous liver
cells.
However, most of these efforts failed, even though the
antibody - IL - 2 combination usually works very well
against cancer cells grown in a lab dish.
Antibody that blocks a «do not eat» flag on
cancer cells turns the immune system
against all tumor types
Another approach, still early in clinical development, uses
antibodies to vaccinate patients
against their own tumours, pushing their immune system to attack the
cancer cells.
Two clinical trials that used
antibodies to block PD - 1 and PD - L1, a related molecule that binds to PD - 1, resulted in significant and long lasting responses
against melanoma skin
cancer, renal
cell (kidney)
cancer, and lung
cancer.
The Stanford investigators found that when they used
antibodies against CD47 to negate this «don't - eat - me» signal, macrophages were able to chew up many of these
cancer cells.