Sentences with phrase «antibodies against the antigen»

Secondly, it helps improve the immunogenicity of some vaccines, which is the body's ability to produce antibodies against the antigen for which the vaccine has been given.

Not exact matches

Spontaneous immune responses were assessed by measuring serum antibodies against ovarian cancer - associated antigens, such as NY - ESO - 1, that are not expressed in normal body tissues but are expressed in cancers.

This «suggests that antibodies specific for this conserved region could provide protection against multiple toxin - mediated clostridium infections and points to a generalizable strategy for generating safe vaccine antigens for this class of toxins,» they concluded.

Antibody formation against sheep erythrocytes by mouse spleen cells in vitro requires interactions among antigen - treated macrophages and lymphoid cells in cell culsters for only a finite time.

These companies must first decide what antigens to make antibodies against, then try to guess how they're likely to be used.

They prepared a similar weapon against liver cancer by piggybacking rhenium 18 on antibodies that target HBx, a viral antigen made by cancerous liver cells.

Without Foxo1, germinal center structure is disorganized and mice could not produce high affinity antibodies against foreign antigens.

Learning what they contribute to cell structure, permeability, membrane biogenesis and so on is important in vaccine research because antibodies against protein antigens can disable the protein's function.»

The study, published in Scientific Reports, demonstrated that animals injected with synthetic DNA engineered to encode a specific neutralizing antibody against the dengue virus were capable of producing the exact antibodies necessary to protect against disease, without the need for standard antigen - based vaccination.

They stimulate the immune system to produce antibodies against the tumour antigens, too.

Hu14.18 K332A is a laboratory - produced antibody designed to activate the immune response against tumor cells by recognizing and binding to an antigen found on the surface of most neuroblastoma tumor cells.

This option is useful when the primary antibodies are from the same host (e.g., a mouse monoclonal against antigen A and a mouse monoclonal against antigen B).

While much recent research has not been published in this area, there is actually a long history of studies that show: (1) there is a significant number of antigens shared between tumors and embryonic tissues (called «oncofetal antigens») and, consequently, antibodies made against tumors can also recognize embryonic tissues, and vice versa; (2) pregnancy confers some immunity against cancer (accompanied by antibody production against oncofetal antigens), not only against its occurrence but also against its growth; (3) similar to pregnancy, an immune response against cancer can be generated by vaccinating animals with embryonic tissues.

Researchers have discovered that a subset of human antibodies have catalytic activity against a particular antigen, breaking it down into smaller and less harmful fragments instead of trapping it for removal or destruction by other immune cells.

This leads the immune system to direct antibodies against the healthy tissue - not just antigens - causing swelling, pain, and tissue damage.

Cross-reactivity occurs when an antibody raised against one specific antigen recognizes two antigens that have similar structural regions.

Gemtuzumab ozogamicin, which is targeted against the CD - 33 antigen, is an antibody conjugated to an anti-tumor agent.

Antibody levels (µg / mL) measuring total IgG against the P. falciparum 3D7 AMA1 vaccine antigen were measured by an enzyme - linked immunosorbent assay (ELISA)[16].

Confocal images of P150 dystrophic retina transplanted with hNPCctx — GDNF and double stained with antibodies against human nuclear antigen (red) and either (A) recoverin, a photoreceptor and cone bipolar cell marker (green), or (B) protein kinase Cα (PKCα), a bipolar cell marker (green).

(C) Confocal image of P150 dystrophic inner retina transplanted with hNPCctx — GDNF and double stained with antibodies against nestin, a neural stem and progenitor cell marker (green) and human nuclear antigen (red).

The difficulty in using monoclonal antibodies against tumor cells is that most of the antibodies raised will be against immunodominant antigens — all the high - visibility proteins that the immune system recognizes.

To raise antibodies against goat MSTN, the C - terminal region of goat MSTN (amino acids 266 — 375) was expressed in bacteria, purified with a nickel column and then used as antigen to immunize rabbits.

This approach involves first generating many monoclonal antibodies raised against «crude» tumor cell antigen populations — whole cells and cell membranes — and then screening for those that block the metastatic ability of the cell.

The antibodies listed above in the immunocytochemistry section were also used on eye sections together with a cocktail of antibodies generated against human - specific markers (HSM) to identify human cells (the Oka blood group antigen, mouse TRA -1-85, 1 ∶ 10 (a kind gift from Peter Andrews, University of Sheffield, Sheffield, UK) together with mouse human nuclear antigen, 1 ∶ 1000, Millipore).

Intestinal permeability was assessed by Ussing chamber; epithelial cell (EC) ultra-structure by electron microscopy; RNA expression of genes coding for junctional proteins by Q - real - time PCR; immune response by in - vitro antigen - specific T - cell proliferation and cytokine analysis by cytometric bead array; intestinal microbiota by fluorescence in situ hybridization and analysis of systemic antibodies against intestinal microbiota by surface staining of live bacteria with serum followed by FACS analysis.

Normally, your immune system has antibodies that protect your body against harmful antigens.

Yasmina Ykelenstam: IgE antibodies were elevated four-fold against processed food antigens in 30 % of humans.

Antibodies against modified food antigens, by reacting with AGEs and tissue proteins, may cause perturbation in degenerative and autoimmune diseases such as diabetes, atherosclerosis, inflammation, autoimmunity, neurodegeneration and neuroautoimmunity.»

Detection of IgE, IgG, IgA and IgM antibodies against raw and processed food antigens https://nutritionandmetabolism.biomedcentral.com/articles/10.1186/1743-7075-6-22 «We conclude that the determination of food allergy, intolerance and sensitivity would be improved by testing IgE, IgG, IgA and IgM antibodies against both raw and processed food antigens.

This is not the first time that antibody levels against an antigen have been found to be more stable and diagnostically useful than levels of the antigen itself (21).

Just as certain disease - causing agents or foreign substances will cause the body to produce antibodies against them, certain proteins are known to act like antigens in celiac disease patients, causing the body to produce antibodies against them.

As stated in Dr. Reuven Yagil's autoimmune paper, «conventional antibodies rarely show a complete neutralizing activity against enzyme antigens, but camel IgG has a full neutralizing activity against tetanus toxin as it enters the enzymes structure.»

These food particles can then be absorbed into your bloodstream, where your body misidentifies them as antigens — substances that shouldn't be there — and then produces antibodies against them.

2) Second, these chemicals must bind to our own tissue proteins creating new antigens (an antigen is any substance that causes your immune system to produce antibodies against it, tagging it for destruction and removal).

Production of these antibodies against the BBB and other neural cell antigens from a cell - mediated and humoral immune response may indicate a pathological alteration of the protective brain barrier.

This is an immunological test for antibody against the «C6 peptide,» a very unique section of the one of the Borrelia burgdorgeri surface antigens.

Immunodiagnosis involves looking for antigens of microfilaria or antibodies against the microfilaria using monoclonal antibody techniques.

This is an immunological test for antibody against the C6 peptide, a unique section of the one of the Borrelia burgdorferi surface antigens.

She explained that when you give a vaccine antigen, which is the protein of the virus or bacteria you're immunizing against, you actually neutralize any existing antibody directed specifically against that same antigen.

Richards, R.L., Rao, M., Wassef, N.M., Glenn, G. M., Rothwell, S. W., Alving, C.R. Liposomes containing lipid A serve as an adjuvant for induction of antibody and cytotoxic T - cell responses against RTS, S malaria antigen.