Successful entrepreneurs have to
anticipate change at every turn and figure out how to adapt every time, even when the market controls the required speed.
Not exact matches
We are reaffirming it again
at this time, with an adjustment to our
anticipated costs forecast under Corporate and Other, which have been increased due to
anticipated under - recoveries on our marine fleet driven by
changes in project schedules.
Actual results and the timing of events could differ materially from those
anticipated in the forward - looking statements due to these risks and uncertainties as well as other factors, which include, without limitation: the uncertain timing of, and risks relating to, the executive search process; risks related to the potential failure of eptinezumab to demonstrate safety and efficacy in clinical testing; Alder's ability to conduct clinical trials and studies of eptinezumab sufficient to achieve a positive completion; the availability of data
at the expected times; the clinical, therapeutic and commercial value of eptinezumab; risks and uncertainties related to regulatory application, review and approval processes and Alder's compliance with applicable legal and regulatory requirements; risks and uncertainties relating to the manufacture of eptinezumab; Alder's ability to obtain and protect intellectual property rights, and operate without infringing on the intellectual property rights of others; the uncertain timing and level of expenses associated with Alder's development and commercialization activities; the sufficiency of Alder's capital and other resources; market competition;
changes in economic and business conditions; and other factors discussed under the caption «Risk Factors» in Alder's Annual Report on Form 10 - K for the fiscal year ended December 31, 2017, which was filed with the Securities and Exchange Commission (SEC) on February 26, 2018, and is available on the SEC's website
at www.sec.gov.
Such risks, uncertainties and other factors include, without limitation: (1) the effect of economic conditions in the industries and markets in which United Technologies and Rockwell Collins operate in the U.S. and globally and any
changes therein, including financial market conditions, fluctuations in commodity prices, interest rates and foreign currency exchange rates, levels of end market demand in construction and in both the commercial and defense segments of the aerospace industry, levels of air travel, financial condition of commercial airlines, the impact of weather conditions and natural disasters and the financial condition of our customers and suppliers; (2) challenges in the development, production, delivery, support, performance and realization of the
anticipated benefits of advanced technologies and new products and services; (3) the scope, nature, impact or timing of acquisition and divestiture or restructuring activity, including the pending acquisition of Rockwell Collins, including among other things integration of acquired businesses into United Technologies» existing businesses and realization of synergies and opportunities for growth and innovation; (4) future timing and levels of indebtedness, including indebtedness expected to be incurred by United Technologies in connection with the pending Rockwell Collins acquisition, and capital spending and research and development spending, including in connection with the pending Rockwell Collins acquisition; (5) future availability of credit and factors that may affect such availability, including credit market conditions and our capital structure; (6) the timing and scope of future repurchases of United Technologies» common stock, which may be suspended
at any time due to various factors, including market conditions and the level of other investing activities and uses of cash, including in connection with the proposed acquisition of Rockwell; (7) delays and disruption in delivery of materials and services from suppliers; (8) company and customer - directed cost reduction efforts and restructuring costs and savings and other consequences thereof; (9) new business and investment opportunities; (10) our ability to realize the intended benefits of organizational
changes; (11) the
anticipated benefits of diversification and balance of operations across product lines, regions and industries; (12) the outcome of legal proceedings, investigations and other contingencies; (13) pension plan assumptions and future contributions; (14) the impact of the negotiation of collective bargaining agreements and labor disputes; (15) the effect of
changes in political conditions in the U.S. and other countries in which United Technologies and Rockwell Collins operate, including the effect of
changes in U.S. trade policies or the U.K.'s pending withdrawal from the EU, on general market conditions, global trade policies and currency exchange rates in the near term and beyond; (16) the effect of
changes in tax (including U.S. tax reform enacted on December 22, 2017, which is commonly referred to as the Tax Cuts and Jobs Act of 2017), environmental, regulatory (including among other things import / export) and other laws and regulations in the U.S. and other countries in which United Technologies and Rockwell Collins operate; (17) the ability of United Technologies and Rockwell Collins to receive the required regulatory approvals (and the risk that such approvals may result in the imposition of conditions that could adversely affect the combined company or the expected benefits of the merger) and to satisfy the other conditions to the closing of the pending acquisition on a timely basis or
at all; (18) the occurrence of events that may give rise to a right of one or both of United Technologies or Rockwell Collins to terminate the merger agreement, including in circumstances that might require Rockwell Collins to pay a termination fee of $ 695 million to United Technologies or $ 50 million of expense reimbursement; (19) negative effects of the announcement or the completion of the merger on the market price of United Technologies» and / or Rockwell Collins» common stock and / or on their respective financial performance; (20) risks related to Rockwell Collins and United Technologies being restricted in their operation of their businesses while the merger agreement is in effect; (21) risks relating to the value of the United Technologies» shares to be issued in connection with the pending Rockwell acquisition, significant merger costs and / or unknown liabilities; (22) risks associated with third party contracts containing consent and / or other provisions that may be triggered by the Rockwell merger agreement; (23) risks associated with merger - related litigation or appraisal proceedings; and (24) the ability of United Technologies and Rockwell Collins, or the combined company, to retain and hire key personnel.
The
changes appear in part to be an effort to offset the
anticipated upswing in labor costs, according to a manager who was implementing the
changes at his store.
The markets are pricing in no
change to Fed policy when the Federal Open Market Committee meets in May, but traders
anticipate another hike
at the June meeting, according to CME Group fed funds futures.
The items we were blind to: our initially incorrect positioning in the market, the time it would take to actually establish operational efficiency and how our metrics would fair in the
changing venture capital landscape, were
anticipated from our mentors after they took an unbiased look
at the business from the outside.
These risks and uncertainties include: Gilead's ability to achieve its
anticipated full year 2018 financial results; Gilead's ability to sustain growth in revenues for its antiviral and other programs; the risk that private and public payers may be reluctant to provide, or continue to provide, coverage or reimbursement for new products, including Vosevi, Yescarta, Epclusa, Harvoni, Genvoya, Odefsey, Descovy, Biktarvy and Vemlidy ®; austerity measures in European countries that may increase the amount of discount required on Gilead's products; an increase in discounts, chargebacks and rebates due to ongoing contracts and future negotiations with commercial and government payers; a larger than
anticipated shift in payer mix to more highly discounted payer segments and geographic regions and decreases in treatment duration; availability of funding for state AIDS Drug Assistance Programs (ADAPs); continued fluctuations in ADAP purchases driven by federal and state grant cycles which may not mirror patient demand and may cause fluctuations in Gilead's earnings; market share and price erosion caused by the introduction of generic versions of Viread and Truvada, an uncertain global macroeconomic environment; and potential amendments to the Affordable Care Act or other government action that could have the effect of lowering prices or reducing the number of insured patients; the possibility of unfavorable results from clinical trials involving investigational compounds; Gilead's ability to initiate clinical trials in its currently
anticipated timeframes; the levels of inventory held by wholesalers and retailers which may cause fluctuations in Gilead's earnings; Kite's ability to develop and commercialize cell therapies utilizing the zinc finger nuclease technology platform and realize the benefits of the Sangamo partnership; Gilead's ability to submit new drug applications for new product candidates in the timelines currently
anticipated; Gilead's ability to receive regulatory approvals in a timely manner or
at all, for new and current products, including Biktarvy; Gilead's ability to successfully commercialize its products, including Biktarvy; the risk that physicians and patients may not see advantages of these products over other therapies and may therefore be reluctant to prescribe the products; Gilead's ability to successfully develop its hematology / oncology and inflammation / respiratory programs; safety and efficacy data from clinical studies may not warrant further development of Gilead's product candidates, including GS - 9620 and Yescarta in combination with Pfizer's utomilumab; Gilead's ability to pay dividends or complete its share repurchase program due to
changes in its stock price, corporate or other market conditions; fluctuations in the foreign exchange rate of the U.S. dollar that may cause an unfavorable foreign currency exchange impact on Gilead's future revenues and pre-tax earnings; and other risks identified from time to time in Gilead's reports filed with the U.S. Securities and Exchange Commission (the SEC).
For example, the expected timing and likelihood of completion of the proposed merger, including the timing, receipt and terms and conditions of any required governmental and regulatory approvals of the proposed merger that could reduce
anticipated benefits or cause the parties to abandon the transaction, the ability to successfully integrate the businesses, the occurrence of any event,
change or other circumstances that could give rise to the termination of the merger agreement, the possibility that Kraft shareholders may not approve the merger agreement, the risk that the parties may not be able to satisfy the conditions to the proposed transaction in a timely manner or
at all, risks related to disruption of management time from ongoing business operations due to the proposed transaction, the risk that any announcements relating to the proposed transaction could have adverse effects on the market price of Kraft's common stock, and the risk that the proposed transaction and its announcement could have an adverse effect on the ability of Kraft and Heinz to retain customers and retain and hire key personnel and maintain relationships with their suppliers and customers and on their operating results and businesses generally, problems may arise in successfully integrating the businesses of the companies, which may result in the combined company not operating as effectively and efficiently as expected, the combined company may be unable to achieve cost - cutting synergies or it may take longer than expected to achieve those synergies, and other factors.
Factors that could cause or contribute to actual results differing from our forward - looking statements include risks relating to: failure of DBRS to rate the Notes
at the
anticipated ratings levels, which is a closing condition, or
at all;
changes in the financial markets, including
changes in credit markets, interest rates, securitization markets generally and our proposed securitization in particular; the willingness of investors to buy the Notes; adverse developments regarding OnDeck, its business or the online or broader marketplace lending industry generally, any of which could impact what credit ratings, if any, are issued with respect to the Notes; the extended settlement cycle for the scheduled closing on April 17, 2018, which may exacerbate the foregoing risks; and other risks, including those described in our Annual Report on Form 10 - K for the year ended December 31, 2017 and in other documents that we file with the Securities and Exchange Commission from time to time which are or will be available on the Commission's website
at www.sec.gov.
At the federal level, the US Department of Energy's much -
anticipated study on grid reliability deliberately removed language noting harm from climate
change between the draft and final versions.
Factors that could cause actual results to differ materially from those expressed or implied in any forward - looking statements include, but are not limited to:
changes in consumer discretionary spending; our eCommerce platform not producing the
anticipated benefits within the expected time - frame or
at all; the streamlining of the Company's vendor base and execution of the Company's new merchandising strategy not producing the
anticipated benefits within the expected time - frame or
at all; the amount that we invest in strategic transactions and the timing and success of those investments; the integration of strategic acquisitions being more difficult, time - consuming, or costly than expected; inventory turn;
changes in the competitive market and competition amongst retailers;
changes in consumer demand or shopping patterns and our ability to identify new trends and have the right trending products in our stores and on our website;
changes in existing tax, labor and other laws and regulations, including those
changing tax rates and imposing new taxes and surcharges; limitations on the availability of attractive retail store sites; omni - channel growth; unauthorized disclosure of sensitive or confidential customer information; risks relating to our private brand offerings and new retail concepts; disruptions with our eCommerce platform, including issues caused by high volumes of users or transactions, or our information systems; factors affecting our vendors, including supply chain and currency risks; talent needs and the loss of Edward W. Stack, our Chairman and Chief Executive Officer; developments with sports leagues, professional athletes or sports superstars; weather - related disruptions and seasonality of our business; and risks associated with being a controlled company.
Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or
at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the
anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid
change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the
anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry (R) World (TM); risks related to the collection, storage, transmission, use and disclosure of confidential and personal information;
Many factors could cause BlackBerry's actual results, performance or achievements to differ materially from those expressed or implied by the forward - looking statements, including, without limitation: BlackBerry's ability to enhance its current products and services, or develop new products and services in a timely manner or
at competitive prices, including risks related to new product introductions; risks related to BlackBerry's ability to mitigate the impact of the
anticipated decline in BlackBerry's infrastructure access fees on its consolidated revenue by developing an integrated services and software offering; intense competition, rapid
change and significant strategic alliances within BlackBerry's industry; BlackBerry's reliance on carrier partners and distributors; risks associated with BlackBerry's foreign operations, including risks related to recent political and economic developments in Venezuela and the impact of foreign currency restrictions; risks relating to network disruptions and other business interruptions, including costs, potential liabilities, lost revenues and reputational damage associated with service interruptions; risks related to BlackBerry's ability to implement and to realize the
anticipated benefits of its CORE program; BlackBerry's ability to maintain or increase its cash balance; security risks; BlackBerry's ability to attract and retain key personnel; risks related to intellectual property rights; BlackBerry's ability to expand and manage BlackBerry ® World ™; risks related to the collection, storage, transmission, use and disclosure of confidential and personal information; BlackBerry's ability to manage inventory and asset risk; BlackBerry's reliance on suppliers of functional components for its products and risks relating to its supply chain; BlackBerry's ability to obtain rights to use software or components supplied by third parties; BlackBerry's ability to successfully maintain and enhance its brand; risks related to government regulations, including regulations relating to encryption technology; BlackBerry's ability to continue to adapt to recent board and management
changes and headcount reductions; reliance on strategic alliances with third - party network infrastructure developers, software platform vendors and service platform vendors; BlackBerry's reliance on third - party manufacturers; potential defects and vulnerabilities in BlackBerry's products; risks related to litigation, including litigation claims arising from BlackBerry's practice of providing forward - looking guidance; potential charges relating to the impairment of intangible assets recorded on BlackBerry's balance sheet; risks as a result of actions of activist shareholders; government regulation of wireless spectrum and radio frequencies; risks related to economic and geopolitical conditions; risks associated with acquisitions; foreign exchange risks; and difficulties in forecasting BlackBerry's financial results given the rapid technological
changes, evolving industry standards, intense competition and short product life cycles that characterize the wireless communications industry.
We define «
anticipate» as evidence of a systematic relationship between points
at which the normalized slope of the ten - day average P / C
changes sign and points
at which the normalized slope of the S&P 500 index
changes sign in the same direction.
This
change is likely a function of investor liquidations in Q4 2016, as markets
anticipated a Fed rate hike, which has since reversed but
at a subdued pace.
Pigs continued to fly in Alberta politics today as energy industry leaders and environmental groups joined Premier Rachel Notley and Environment and Parks Minister Shannon Phillips
at a press conference to release Alberta's much
anticipated plan to take action against Climate
Change.
Quinn Hillyer
at National Review is calling the
anticipated change in the U.S. $ 10 note «outrageous and ignorant.»
At the raw bar's intimate six seats, guests can
anticipate a fun, interactive and ever -
changing menu.
It's understood that the contract offer for the Frenchman remains on the table, but after 20 years
at the club, a
change is highly
anticipated.
This guide is intended to provide an estimate for common 2 - 3 year olds developments children reach
at this age, but you will need to consider the unique context of your child's development as you try to
anticipate the
changes in your child.
This helps your child
anticipate the
change and gives them something to look forward to
at their other home.
If you're able to
anticipate that potty - training accident on the way to daycare, for example, and keep an extra
change of clothes in your car
at all times, a near - catastrophe becomes an easy fix.
At one point in Alex Salmond's much -
anticipated tome, The Dream Shall Never Die: 100 Days that
changed Scotland forever, he reflects on never having written a book — «loads of pamphlets, speeches and White Papers, but never a book».
I
anticipate my resolution will receive unanimous support
at the Legislature's next session, and that Erie County will join efforts to bring overdue
change and help to our local neighborhoods.
These include lowering expense projections for retirement and health insurance expense to reflect lower projected usage and rates not available
at the time the budget request was prepared; lowering utility cost estimates to reflect the significant decline in energy demand and prices resulting from reduced economic activity and lowering other operating cost estimates to reflect lower
anticipated price
changes.
Buffalo News Political Reporter Bob McCarthy
anticipates that
changing following Tuesday's debate
at St. Joseph's Collegiate Institute.
In the announcement, Exelon said it does not
anticipate any
changes in staffing levels
at this time.
Still, it is undeniable that a variety of 21st - century forces — a new generation in the military, a
change in climate
at the top levels of the Pentagon, pressure on the president from a critical interest group, even Senator Kirsten E. Gillibrand's
anticipated Democratic primary battle in New York — converged to begin repeal of a 1993 law that has led to the discharge of more than 13,000 gay men and lesbians, including desperately needed Arabic translators.
Steve Madarasz, a spokesman for the Civil Service Employees Association, said CSEA doesn't
anticipate any big
changes in 2012 but «whenever you have a SAGE commission looking
at consolidations and mergers we're going to have concerns.»
In the current study, Whitney, along with colleagues John Hinson, WSU professor of psychology, and Hans Van Dongen, director of the WSU Sleep and Performance Research Center
at WSU Spokane, compared how people with different variations of the DRD2 gene performed on tasks designed to test both their ability to
anticipate events and their cognitive flexibility in response to
changing circumstances.
For example, he says, although the new study found no overall
change in the rate of melting
at Totten Glacier over the last couple of decades, the large variability in melting rate within those decades warrants a much closer look
at the region's complex topography, among other factors, in order to
anticipate how the system could actually
change in the future.
As the craft ploughs deeper into the galaxy, the NASA team will look for an
anticipated change in magnetic field direction that would indicate that Voyager 1 is
at last clear of all solar influences except gravity, as well as anything that can be gleaned about interstellar space, before we lose contact.
From this position, said Hogg, and with the European Union, it was able to set the pace
at the recent meeting in Berlin of parties to the Climate
Change Convention and to win agreement for a much tougher mandate than was originally
anticipated.
But Varmus says the award should start
at a «small scale» because it is hard to
anticipate how it will «
change the structure» of a lab and its workforce.
Looking
at previous work on other addictions, such as alcoholism, we
anticipated that pathological gamblers would have increased opiate receptors which we did not find, but we did find the expected blunted
change in endogenous opioids from an amphetamine challenge.
Now the National Science Foundation (NSF), along with the U.S. Energy and Agriculture departments are teaming up to financially support the development of new computer models aimed
at revealing the
anticipated effects of climate
change at the regional level.
«As Earth continues to warm, it may be approaching a critical climate threshold beyond which rapid and potentially permanent —
at least on a human time - scale —
changes not
anticipated by climate models tuned to modern conditions may occur,» the report says.
Knowledge of these thresholds is key to the sustainable management of ecosystems and to
anticipating irreversible
changes and / or ecological collapse,» wrote Alfredo Huete, a researcher
at the University of Sydney in Australia, in an accompanying commentary on the study in Nature.
When I got home my sweet / amazing / loving husband said «it looks nice», not a bad reaction
at all... but not exactly the reaction I had
anticipated considering I thought I made such a huge
change!
I mostly just can't wait for some of the
changes I'm
anticipating... like new car delivery, new furniture delivery, and of course the completion of Eddie's hard work
at the clinic.
They also looked
at the school schedule, staffing
changes, implications from the previous year, and
anticipated professional development needs for the beginning of the school year.
Although Nissan has only released information about the Euro - spec 2015 Nissan Juke
at this point, we don't
anticipate any
changes to the American - market car's 1.6 - liter turbocharged four - cylinder engine.
«We learned a lesson
at Road America when the temperature
changed more than we had
anticipated and affected the balance of the car,» Magnussen said.
For the much
anticipated 2015
ATS Coupe, Cadillac engineers and designers made a number of
changes from the award - winning
ATS Sedan to deliver the performance and styling traits luxury coupe buyers expect.
Babur Habib, co-founder of educational software and digital textbook designer Kno, was on hand
at Tools of
Change to speak with GoodEReader about its recent launch of the Kno Advance platform, the
anticipated follow up to the earlier release of the Kno Me interactive learning dashboard.
We wouldn't
anticipate this particular slate carrying a quad - core chip to tackle the Nexus 7 head - on, though — unless the KFTT variant is just a firmware - updated Kindle Fire with a name
change, the next generation should still have
at least one dual - core tablet in the range.
At its best, DBW
anticipated the
changes that were coming in the industry and gave its attendees practical ways to think about and cope with them.
If an income gap is
anticipated during retirement, perhaps it can be eliminated through lifestyle
changes in your fifties and sixties - for example, by saving
at a higher rate, working longer, tapping into home equity, or deciding to have a less luxurious lifestyle in retirement.
The
anticipated changes will be felt primarily by would - be FHA borrowers with a low credit score, loan applicants who have experienced a foreclosure, and borrowers
at the high end of FHA loan limits.