Malathi, K., Dong, B., Gale, M., and Silverman, R.H. Small Self RNA Generated by RNase L Amplifies
Antiviral Innate Immunity.
Jha, B.K., Dong, B., Nguyen, C.T., Polyakova, I. and Silverman, R.H. Suppression of
antiviral innate immunity by sunitinib enhances oncolyticvirotherapy.
Sorgeloos, F., Jha, B.K., Silverman, R.H., and Michiels, T.Evasion of
antiviral innate immunity by Theiler's virus L * protein through direct inhibition of RNase L.PLoS Pathogens, Epub, 2013.
Jha, B.K., Polyakova, I., Kessler, P., Dong, B., Dickerman, B., Sen, G.C., and Silverman, R.H. Inhibition of RNase L and RNA - dependent protein kinase (PKR) by sunitinib impairs
antiviral innate immunity.
Not exact matches
«Our compound has an
antiviral effect against all these viruses,» said Michael Gale Jr., University of Washington professor of immunology and director of the UW Center for
Innate Immunity and Immune Disease.
Areas for future focus will be to develop mechanisms of boosting host defence and
innate immunity so
antivirals / antibacterials will be less required.
More investment into research is all the more important given that we are close to formidable breakthroughs in many areas of respiratory diseases, such as molecular bacteriology and virology, development of vaccines and
antiviral agents, boosting host defence and
innate immunity, molecular pathology and personalised care for lung cancer.
Innate immunity against bacterial and fungal pathogens is mediated by Toll and immune deficiency (Imd) pathways, but little is known about the
antiviral response in Drosophila.