Key points include that surgeons are adapting their surgical strategies to more aggressively treat
aortic dissections with improved outcomes.
Not exact matches
According to the research, patients
with a hereditary predisposition for
aortic dissection and a dilation of the aorta also appear to have an increased
aortic stiffness.
Thoracic
aortic aneurysm and
dissection (TAAD), an enlargement or tearing of the walls of the aorta in the chest, is, together
with abdominal
aortic aneurysms, responsible for about 2 % of all deaths in Western countries.
These complex
aortic dissection surgeries benefit from cerebral perfusion,
with 85 % of cases currently using the technique.
«Type A
aortic dissection requires emergency surgical repair,» said senior author Ravi K. Ghanta, MD, formerly of the University of Virginia in Charlottesville, now
with Baylor College of Medicine in Houston.
Through genetic analysis of a family
with a history of thoracic
aortic aneurysm and
dissection (TAAD), investigators at Brigham and Women's Hospital and Washington University School of Medicine in St. Louis have identified mutations in the LOX gene, a gene associated
with the integrity of the arterial wall, in human subjects for the first time.
«Patients
with this mutation may merit earlier surgical therapy, before
aortic dissection has a chance to occur,» Elefteriades says.
In the appropriate clinical setting, suspicion for acute
aortic dissection should be raised when patients present
with findings that have a high specificity and high positive likelihood ratio (hypotension, pulse deficit,...
Patients
with one or more high - risk clinical features (tearing pain, hypotension, pulse deficit, neurologic deficit, new murmur) should be considered high risk for acute
aortic dissection (AAD).
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