Sentences with phrase «apical cell surface»

Internalization of POS is observed in a single optical y - axis projection (< 1 µm) of pigmented iPS - RPE cells labelled with the apical cell surface marker ATP1B1 (red).

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These organoids form all of the cell types present in human intestine, but they grow as cysts surrounded by thick extracellular matrix gels with their «apical» cell surface (which is normally exposed to the content of the gut) facing an enclosed lumen.

Following this, cells undergo shape changes and organise around a central lumen, with their apical (top) surfaces facing the lumen, the basal (bottom) surfaces interacting with the underlying tissue and the lateral (side) surfaces in close contact with the neighbouring cells.

In the Intestine Chip, the epithelium forms villi - like projections lined by polarized epithelial cells that undergo multi-lineage differentiation similar to that of intestinal organoids, however, these cells expose their apical surfaces to an open lumen and interface with endothelium.

aRG cells are highly elongated, extending a basal process all the way to the pial surface of the developing brain and an apical process that remains in contact with the ventricular surface (Fig. 1).

In response to extracellular matrix signalling, these cells undergo epithelialization and create an apical surface in contact with a cavity, a fundamental event for all subsequent development.

The apical surface of the RPE cells is identified by ATP1B1 (red).

Primary kidney epithelial cells isolated from human proximal tubule are cultured on the upper surface of an extracellular matrix - coated, porous, polyester membrane that splits the main channel of the device into two adjacent channels, thereby creating an apical «luminal» channel and a basal «interstitial» space.

Enzymes are stored in zymogen granules within the acinar cell in the presence of pancreatic secretory trypsin inhibitor (PSTI) and are released at the apical surface directly into the duct system.

B. Focus on the apical surface of the ciliated epithelial cell.

A. Microscopic view of the respiratory mucosa consisting of ciliated epithelial cells (i.e. presence of cilia at their apical surface).