Sentences with phrase «apolipoprotein concentrations»
ROC curve analysis: an example showing the relationships among serum lipid and apolipoprotein concentrations in identifying patients with coronary artery disease
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In a genome - wide analysis of up to 17 503 participants in PROMIS, we identified genetic variants associated with either apolipoprotein (a) isoform size or lipoprotein (a) concentration.
We used a genetic approach to distinguish the relevance of two distinct components of this pathway, apolipoprotein (a) isoform size and circulating lipoprotein (a) concentration, to coronary heart disease.
Methods: In this mendelian randomisation study, we measured lipoprotein (a) concentration and determined apolipoprotein (a) isoform size with a genetic method (kringle IV type 2 [KIV2] repeats in the LPA gene) and a serum - based electrophoretic assay in patients and controls (frequency matched for age and sex) from the Pakistan Risk of Myocardial Infarction Study (PROMIS).
Finally, we compared phenotypic versus genotypic ORs to estimate whether apolipoprotein (a) isoform size, lipoprotein (a) concentration, or both were causally associated with coronary heart disease.
Specifically, the researchers looked at mutations in the apolipoprotein A5 gene, a known determinant of triglyceride concentrations.
Alfalfa seeds lower low density lipoprotein cholesterol and apolipoprotein B concentrations in patients with type II hyperlipoproteinemia.
Consumption of fructose - sweetened beverages for 10 weeks increases postprandial triacylglycerol and apolipoprotein - B concentrations in overweight and obese women.