Sentences with phrase «apoptotic pathway»
The phrase "apoptotic pathway" refers to a series of steps or processes that occur within a cell to trigger and carry out programmed cell death, known as apoptosis. It is a natural mechanism the body uses to remove old, damaged, or unwanted cells. The apoptotic pathway helps maintain proper cell balance and is crucial for the normal development and functioning of organisms. Full definition
Indeed, several key players of the intrinsic apoptotic pathway were differentially regulated in their levels when comparing the epithelial and the mesenchymal subpopulation.
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Since amiodarone HCL is known to exert its cytotoxic effect through the extrinsic, caspase - 9 independent apoptotic pathway [33] our microarray results confirm that the differential cytotoxic effect seen in NSCs treated with amiodarone HCL is due to specific activation of extrinsic apoptosis pathways resulting from exposure to the drug.
Using a C. elegans model for Duchenne MD we showed that mitochondrial dynamics and apoptotic pathways plays a key role in dystrophin - dependent muscle degeneration.
Analysis of mitochondrial dynamics, unfolded protein response and apoptotic pathways during muscle degeneration
Her thesis was entitled «Caspase activation in unidentified apoptotic pathways.»
Zoledronic acid reverses cisplatin resistance in nasopharyngeal carcinoma cells by activating the mitochondrial apoptotic pathway.
His small sculpture «Intrinsic Apoptotic Pathways» (2013) is a cast made from a kapala skullcup.
Mitochondria play a critical role in several metabolic processes and apoptotic pathways, regulating life cycle from the cradle to the grave.
Abstract: Mitochondria play a critical role in several metabolic processes and apoptotic pathways, regulating life cycle from the cradle to the grave.
These findings suggest that inhibition of mTOR induces apoptosis by modulating the expression of proteins involved in both extrinsic and intrinsic (mitochondrial) apoptotic pathways.
When a cell or its genetic material is damaged beyond repair, that cell will most often commit itself to the apoptotic pathway and be eliminated from the body.
Furthermore, we show that induction of apoptosis following inhibition of mTOR signaling involved both the extrinsic (c - FLIP) and the intrinsic (MCL - 1 and BCL - 2) apoptotic pathways.
In the case of cancer, however, the apoptotic pathway is circumvented because of the specific genes involved.
Symposia X: The Impact of Heat Shock Protein Expression on Muscle Metabolism, Exercise Capacity and Disease Prevention Speakers will present evidence for the functional effects and mechanisms of heat shock proteins and their role in aging, mitochondrial function, apoptotic pathways, insulin sensitivity, myocardial protection and more.