«The use of a mouse tumor - derived matrix would limit any future
applications of these organoid technologies in humans, and this work opens the door to research directed specifically for clinical applications,» noted Asma Nusrat, study co-author and the Aldred Scott Warthin Professor and Director of Experimental Pathology in the University of Michigan's School of Medicine.
BAR HARBOR, MAINE — The MDI Biological Laboratory in Bar Harbor, Maine, has announced that it will offer a one - week intensive course May 27 through June 2, 2018 entitled «
Applications of Organoid Technology» in partnership with Hubrecht Organoid Technology (The HUB), a non-profit organization based in Utrecht, Netherlands.
This article provides an overview of the wide - ranging
applications of organoids.
The MDI Biological Laboratory has announced that it will offer a one - week intensive course May 27 through June 2, 2018, entitled «
Applications of Organoid Technology» in partnership with Hubrecht Organoid Technology (The HUB), a non-profit organization based in Utrecht, Netherlands.
Hugo de Jonge, an associate professor at Erasmus Medical Center in The Netherlands and director of the MDI Biological Laboratory's new biomedical innovation course, «
Applications of Organoid Technology,» discusses the potential of this fascinating new «mini-organ» technology in this exclusive editorial in Regenerative Medicine Network.
Not exact matches
As such, it provides a means
of moving
organoids from basic research to actual pharmaceutical and clinical
applications in the future.
Beyond the intestinal
applications, the researchers are also studying the use
of hydrogels to deliver
organoids to damaged kidneys and lungs.
Thirdly, the current, almost universal dependency
of organoid culture on the use
of Matrigel as a replacement for the function
of the extracellular basement matrix in providing structural support and survival signals to the epithelial cells hampers clinical
application, considering its origin from a mouse sarcoma cell line, its poorly defined composition and its mechanical rigidity after plating.
Patient - derived
organoids offer great promise for
application in the field
of translational medicine, in particular for autologous transplantation and tissue regeneration purposes (4 - 6).
Here we report a new method for the isolation and propagation
of human cholangiocytes from the extrahepatic biliary tree in the form
of extrahepatic cholangiocyte
organoids (ECOs) for regenerative medicine
applications.