Sentences with phrase «approach in some human patients»

Not exact matches

In spite of his fascination with theory, Jung observed: «It is a remarkable thing about psychotherapy: you... can cure only from one central point; that consists in understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.&raquIn spite of his fascination with theory, Jung observed: «It is a remarkable thing about psychotherapy: you... can cure only from one central point; that consists in understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.&raquin understanding the patient as a psychological whole and approaching him as a human being, leaving aside all theory and listening attentively to whatever he has to say.»

Bolton combined these human hearing models with model checking (an automated, computational approach for finding problems in complex systems) to assess masking in a common patient - monitoring device with six different alarms.

These techniques include: human tissue created by reprogramming cells from people with the relevant disease (dubbed «patient in a dish»); «body on a chip» devices, where human tissue samples on a silicon chip are linked by a circulating blood substitute; many computer modelling approaches, such as virtual organs, virtual patients and virtual clinical trials; and microdosing studies, where tiny doses of drugs given to volunteers allow scientists to study their metabolism in humans, safely and with unsurpassed accuracy.

«If this approach works in humans, it will really change the conversation that providers have with patients,» Scadden said, especially for those «who have these underlying genetic disorders and for who the new gene - editing and gene therapy techniques are being developed.»

Still, Zon cautions that not all human drugs work in zebrafish, so «we need to study a lot more patients to see, in a broad view, how this approach performs.»

The researchers are now testing this approach in mice, and they envision that eventually the technology could be adapted to deliver the CRISPR components to treat infections or remove other unwanted bacteria in human patients.

While more research is needed to determine whether these approaches could help PD patients, Dr. Greenamyre is optimistic that one or both may ultimately make it into human clinical trials in an effort to slow or halt the otherwise inevitable progression of PD.

For example, although early clinical trials of Listeria - based vaccines have shown that the neutralized bacterium produces only mild flulike symptoms in human patients with cervical cancer, the various methods of genetically disarming the bacteria should be explored to find the safest approach for people gravely ill with pancreatic cancer, because these patients are likely to already have weak immune systems.

They will study human macrophages and dendritic cells isolated from IBD patients with defective GM - CSF function, «The approach represents a step forward in personalizing how we treat patients with IBD,» said Dr. Colombel.

Beilhack and colleagues found that a slightly modified version of STAR2 has a similar effect on human T reg cells, suggesting that the approach could also prevent GvHD in leukemia and lymphoma patients after bone marrow or hematopoietic stem cell transplants.

To test the safety of the approach in humans, the team treated 10 LINCL patients ranging in age from 3 to 10 years, starting in 2004.

Dr. Sonntag studies this concept on the molecular and cellular level using a translational research approach that integrates the analysis of human material, such as postmortem brains, primary cell systems, and neural cell populations generated from patients» - or healthy individuals» - derived induced pluripotent stem cells (iPSC), or induced neurons (iNs), in combination with molecular, biochemistry, and lentivirus - mediated gene - engineering technologies.

And, while the genetically - modified mice were made somewhat better by deactivating the HD gene in their hypothalamus, this approach isn't useable in human HD patients because their HD genes don't contain the sequences needed to turn them off with virus used by Petersen and colleagues.

This noninvasive approach could pave the way to using optogenetics in human patients to treat epilepsy and other neurological disorders, the researchers say, although much more testing and development is needed.

But the approach used to reduce «depression» in the mice is not useful for human HD patients, because it relies on genetic tricks that only work in the BAC - HD mice.

«Our approach allowed us to grow human neurons in a dish that contained the exact same mutation as the neurons in the brain of the patient,» explained first author Helen Fong, PhD, who is also a California Institute for Regenerative Medicine postdoctoral scholar.

One of the results of this collaboration is that we were able to take a basic science finding from Andrew Huberman's lab that certain layers in the retina are affected early in glaucoma — and we're immediately able to develop engineering approaches to see some of those changes in human patients with glaucoma.

Dr. Blaser is identifying the factors that promote successful engraftment of transplanted cells in animal models, which he will then attempt to translate into improved approaches for human patients.

Although this approach has yet to be tested in humans, this study suggests that combining two existing cancer immunotherapies can significantly boost their efficacy, resulting in better outcomes for patients.

A functional connectivity approach at the subregional level may therefore yield novel insights into GAD.To determine whether distinct connectivity patterns can be reliably identified for the basolateral (BLA) and centromedial (CMA) subregions of the human amygdala, and to examine subregional connectivity patterns and potential compensatory amygdalar connectivity in GAD.Cross - sectional study.Academic medical center.Two cohorts of healthy control subjects (consisting of 17 and 31 subjects) and 16 patients with GAD.Functional connectivity with cytoarchitectonically determined BLA and CMA regions of interest, measured during functional magnetic resonance imaging performed while subjects were resting quietly in the scanner.

«The development of a functional human kidney glomerulus chip opens up an entirely new experimental path to investigate kidney biology, carry out highly personalized modeling of kidney diseases and drug toxicities, and the stem cell - derived kidney podocytes we developed could even offer a new injectable cell therapy approach for regenerative medicine in patients with life - threatening glomerulopathies in the future,» said Ingber.

Our primary experimental approach involves creation of engineered mouse strains with informative genetic mutations, characterizing these mice and their cells to elucidate molecular mechanisms underlying cancer phenotypes, and verifying these mechanisms in human cancer patient specimens.

Yerkes National Primate Research Center researchers are the first to show that an irradiation plus transplantation combination approach in nonhuman primates can be used to treat or even possibly cure HIV / AIDS, and this new model is providing some answers about the «Berlin patient,» the only human thought cured of AIDS.

«A fundamental weakness inherent in this approach is that one makes assumptions concerning the relevance of the phenotypes and the mechanisms underlying them to the actual disease process going on in a human patient,» Gusella said.

I am currently working to complete my master's degree in Human Nutrition and Functional Medicine from the University of Western States, a science - based and patient - centered approach to health that focuses on treating the person by first assessing the underlying cause of disease.

There are human physicians who still feel that it is a better predictor of approaching mortality in their patients than creatinine.

Training is presented with a «real world» approach by Tom Rinelli who has 25 + years field experience as a (human) medic and educator administering these skills to both two or four legged patients in the field.

Results driven health and human services expert with distinct analytical skills and a wholly professional approach to evaluating overall effectiveness and providing the crucial decisions that result in smooth, seamless operations; seeks position where working knowledge will be fully utilized and expanded, with particular emphasis on: Managed Care / Health Services Risk Management / Patient Safety Consulting / Advisory Serv...