Sentences with phrase «approaches of aggregation»

The theory and approaches of aggregation testing are too broad a topic to cover here, but the general concept is this: by grouping individual rare variants into a biological unit — most often, a gene or exon — it's possible to test the super-genotype (i.e. «has a rare variant in gene A») for association.

Not exact matches

However, this approach requires precision engineering of nano - features (in a detection chip), complex optical setups, novel nano - probes (such as graphene oxide, carbon nanotubes, and gold nanorods) or additional amplification steps such as aggregation of nanoparticles to achieve sensitive detection of biomarkers.

This confirms our assumption that the suppression of the aggregation of proteins represents a promising therapeutic approach for a large number of neurodegenerative disorders that are currently still incurable,» says Hartl, summarizing the results of the study.

I say that not due to any preference for a hierarchical approach to school administration, but in recognition of the need for aggregation in identifying effective interventions.

Although the obvious answer seems like it should be a simple aggregation of all headings for all sections, practically there are a number of usability challenges to this approach.

This proposes expansion of the CDM's Programme of Activities approach to enable aggregation of city - based GHG mitigation reductions broadly covered by five sectors: energy, transport, solid waste, water and wastewater, and urban forestry.

Prepare a «traceable account» of how the [uncertainty] estimates were constructed that describes the writing team's reasons for adopting a particular probability distribution, including important lines of evidence used, standards of evidence applied, approaches to combining / reconciling multiple lines of evidence, explicit explanations of methods for aggregation, and critical uncertainties.

Following Gregg v Scott [2005] 2 AC 176, [2005] 4 All ER 812 and Hicks v Chief Constable of the South Yorkshire Police [1992] All ER 65 and rejecting the aggregation theory approach, Lord Hoffmann observed that neither the risk of injury nor anxiety at the prospect of future injury were in themselves actionable.