Sentences with phrase «approved drugs»

Recently - approved drugs such as oral cyclosporine hold promise for severely atopic dogs.

Currently clomipramine and fluoxetine are the only FDA - approved drugs for the treatment of separation anxiety in the dog; however, other human anti-anxiety medications have a long history of use for this purpose.

Dr. Green says there are more effective, safer, and approved drugs that veterinarians have in their pharmacies.

Fighting for his life and against the system, Ron begins to take and distribute non-FDA approved drugs extending his life, as well as others infected with the disease.

Some FDA - approved drugs can help control autism symptoms.

FDA - approved drugs can not be ingredients in dietary supplements.

There is far more evidence demonstrating the safety and efficiency of coconut oil than there are for most FDA approved drugs.

Ten percent of all FDA approved drugs are later recalled or banned and designated as «Bad Drugs».

Ten percent of FDA approved drugs are later banned, and another ten per cent are given a «black box» warning.

It is used as a base in over 400 plus FDA approved drugs!

Women's groups that advocated for the drug's approval under the campaign, Even the Score, framed the issue as sexist, arguing there are 26 approved drugs for sexual dysfunctions among men but none for women.

There are three FDA - approved drugs on the market: sibutramine (Meridia), orlistat (Xenical), and a low - dose version of orlistat that is sold over the counter (Alli).

This Act became effective in 2011 and specifies that the benefit and harm of newly approved drugs must be assessed in comparison with conventional treatments.

In conclusion, we have developed a screening strategy that allows us to rapidly identify clinically approved drugs for use in a Chemistry, Manufacture and Control protocol that can be safely used to deplete unwanted contaminating precursor cells from a differentiated cell product.

With this optimized platform we screened a collection of FDA - approved drugs to identify compounds that have differential toxicity to hESCs and their neural derivatives.

To date, only 100 or so of the more than 20,000 genes in the human genome have been developed as targets for FDA - approved drugs.

That automation is a clear selling point for Matthew De Silva, whose company, Notable Labs, is trying to devise personalized treatments for brain cancer by testing combinations of thousands of Food and Drug Administration — approved drugs against each individual patient's tumor cells.

In conclusion, we describe a method using hESCs and their differentiated neural derivatives that permits the rapid screening of clinically approved drugs for compounds that can be safely used to selectively deplete progenitor cells from a differentiated cell product.

To identify compounds that are toxic to hESCs, hESC - derived NSCs, or both, we screened 720 FDA - approved drugs of the NINDS collection by testing the toxicity of each drug at a dose of 2.5 µM.

He has played a key role in the discovery and development of multiple approved drugs, including imatinib (Gleevec), dasatinib (Sprycel), and enzalutamide (Xtandi).

Approved Drugs drugs that have been approved by the Food and Drug Administration (FDA) for use in humans, for a specified indication.

No approved drugs exist to even slow the progression of this relentless disorder.

«There are 26 FDA approved drugs to treat various sexual dysfunctions for men,» the Even the Score website reads, «but still not a single one for women's most common sexual complaint.»

DeepDDI was first used to predict DDI types of 2,329,561 drug pairs from all possible combinations of 2,159 approved drugs, from which DDI types of 487,632 drug pairs were newly predicted.

She explores solid tumor analysis by NGS, explaining that annotation is directed at FDA - approved drugs in selected tumor types.

Researchers screened a comprehensive library of approved drugs for anti-HCV activity and found a common over-the-counter allergy drug that lowered HCV levels in infected mice.

Despite widespread use of currently - approved drugs, approximately 40 % of patients with heart failure die within 5 years of their initial diagnosis.

CML: The United States Food and Drug Administration has approved drugs that will lower CML Clinical trials are currently underway for patients who have developed resistance to these medications.

Overall scheme of Deep DDDI and prediction of food constituents that reduce the in vivo concentration of approved drugs.

FDA - approved drugs have already passed safety tests.

«We found that genes associated with successful FDA - approved drugs have several properties at the network, sequence, and tissue - expression levels that significantly distinguish them from other human genes,» the authors conclude.

The study includes a detailed picture of the proteins that are linked to cancer, the number of proteins present in the bloodstream, and the targets for all approved drugs on the market.

For wet AMD, treatments aimed at stopping abnormal blood vessel growth include FDA - approved drugs called Lucentis, Eylea, Macugen and Visudyne used with Photodynamic Therapy or PDT.

We already have, since some approved drugs intervene in cancer cells» specific metabolic needs, but research into how altered metabolism promotes cancer is leading to more directed efforts.

Cholinergic neurons are among the first to be lost in AD [86, 87] and acetylcholine is the therapeutic target for most FDA approved drugs for AD [88, 89].

«An estimated 40 % of approved drugs and nearly 90 % of the developmental pipeline drugs consist of poorly soluble molecules.

To date, a screen of the collection of FDA - approved drugs in the Prestwick Library has identified a handful of potential candidates which have demonstrated effectiveness at lowering secretion of IL - 6, a component of SASP whose concentration tends to rise systemically with aging and here used as a preliminary marker of SASP as a phenotype.

And yet no approved drugs exist to prevent, halt or reverse this debilitating disease — which robs people of memory, other critical brain functions and, ultimately, their life.

We have tested over 160 experimental compounds and approved drugs in this testing pipeline at PsychoGenics (PGI).

Using a new mouse model, we propose to test whether the spread of tangles through the brain is a result of abnormal tau overwhelming the cell's ability to clear it and whether we can boost cell defenses against tangles using clinically approved drugs that have not been used for this purpose previously.

But that optimism, plus the availability of FDA - approved drugs with an HDAC inhibitory effect, has also prompted many families to find doctors who will prescribe these drugs, without knowing whether they work, or at what doses, or in which subset of patients.

This method is used by 80 % of major pharmaceutical companies and has contributed to the development of several approved drugs.

The process they have followed in order to gather the specific information was to extract from the published literature all pharmacogenomic biomarkers that relate to the US Food and Drug Administration (FDA) and the European Medicines Agency (EMA) approved drugs with pharmacogenomic information in their label and make them available in a database that triangulates between drugs, genes and pharmacogenomics biomarkers.

Screening of FDA - approved Drugs and Identification of Novel Lassa Virus Entry Inhibitors — Peilin Wang — bioRxiv

Using FDA - approved drugs, which have already passed safety tests, can help bring treatments to patients more quickly.

There are no approved drugs that specifically target sepsis.

Research teams are also developing ways to innovate the early drug - discovery process, including pioneering methods to rapidly identify drug targets and test them on laboratory models and finding and testing new therapeutic possibilities for already FDA - approved drugs.

«We therefore used these as a probe in a competition binding assay and screened approximately 8,200 chemical compounds, including both approved drugs and other known bioactive compounds.»

There are no Food and Drug Administration (FDA)-- approved drugs for the disease.

The new prescription medication is a combination of two FDA - approved drugs, bupropion, an antidepressant and naltrexone, which reduces the desire for drugs and alcohol.