Sentences with phrase «approved small molecule drug»

Not exact matches

TLC's first project, which is also a pilot project of the TRND program, focuses on repurposing an existing small molecule drug, auranofin, initially approved to treat rheumatoid arthritis in the mid-1980s.

In 1994, Schreiber and co-workers discovered that the proteins FKBP12 and mTOR are the simultaneous targets of the small molecule rapamycin, now approved for use as an immunosuppressant drug given to patients after organ transplantations to help prevent rejection.

It also raises the possibility to interfere with these systems by any means (small molecules, FDA approved marketed drugs) and evaluate the consequences on both neurogenesis and neuroplasticity.