The use of corticosteroids to treat other conditions is known to cause an increased resistance to
aqueous humor outflow and elevated IOP.
TGF - Î ² 2 is known to elevate IOP by promoting increases in
aqueous humor outflow resistance through the trabecular meshwork.
«Schlemm's canal endothelial cells are believed to be one of the resistance sites crossed by the aqueous humor before entering the blood circulation and are likely to play an important role in the regulation of
aqueous humor outflow resistance.
While the cause of changes in
aqueous humor outflow resistance remain unclear, it has been established that the amount of transforming growth factor - beta2 (TGF - Î ² 2) is increased by 60 - 70 % in the aqueous humor of POAG patients.
This project developed an in vitro model using 3D porous polymer for studying
the aqueous humor outflow in the eye.
Project: Nanoengineered In Vitro Trabecular Meshwork ™ Model for Systematic Investigation of
Aqueous Humor Outflow Resistance
Summary: Patients with primary open - angle glaucoma (POAG) often present with chronically elevated intraocular pressure (IOP), the result of increased resistance to
aqueous humor outflow through the trabecular meshwork.
Not exact matches
The objective of my proposal is to determine how neuronal control regulates
aqueous humor (AQH)
outflow and intraocular pressure (IOP).