Sentences with phrase «areas of the genome where»

They found four key areas of the genome where specific SNPs correlate with skin color.

The locus sits close to an area of the genome where humans and chimps are known to share specific combinations of genes.

Not exact matches

To avoid that muddle, Steve Brown and Xue - Zhong Liu, molecular biologists at the Medical Research Council's Mouse Genome Center in Harwell, England, sought families in remote areas of the world, where the families» deafness is more likely to be caused by a single mutated gene.

Researchers have previously harnessed this system to create gene - editing complexes composed of a DNA - cutting enzyme called Cas9 and a short RNA that guides the enzyme to a specific area of the genome, directing Cas9 where to make its cut.

The goal was to initiate an informed discussion of the uses of genome engineering technology, and to identify those areas where action is essential to prepare for future developments.

By better understanding the limitations of genome - wide sequencing, Vogelstein notes, researchers and policymakers might be better able to direct funding and efforts to areas, such as Alzheimer's disease, where a person's genetic profile might have a very real effect on their likelihood of getting the disease.

Knowledge of where the ribonucleotides cluster could help identify areas of greatest potential for genome instability and lead to a better understanding of how they affect the properties and activities of DNA.

Each of the working groups is responsible for developing a proposal for a set of genomes to sequence that would advance knowledge in one of three important scientific areas: identifying areas in genetic research where the application of high - throughput sequencing resources would rapidly lead to significant medical advances; understanding of the human genome; and understanding the evolutionary biology of genomes.

This revealed a significantly greater number of genome areas where spontaneous DNA deletions and duplications «hit» genes thought to contribute substantially to ASD.

Functional genomic elements, for example, are expected to be found at higher density in genome regions with a high recombination rate where fewer slightly deleterious mutations accumulate than in areas of low recombination [13].