Sentences with word «arginase»

Arginase enzymes maintain lower levels of free arginine in the blood and tissue.

In particular, fetal cells made high amounts of arginase - 2, an enzyme that breaks down L - arginine, a key ingredient in the production of a key messenger named tumor necrosis factor alpha (TNF - alpha).

Blocking arginase using the small drug difluoromethylornithine (DFMO) before the start of symptoms in the mice, the scientists saw fewer CD11c microglia and plaques develop in their brains.

Abbreviations: CPS1 = carbamoyl - phosphate synthase; OTC = ornithine carbamoyltransferase; ASS1 = argininosuccinate synthase; ASL = argininosuccinate lyase; and ARG1 = arginase - 1.

Transgenic mice overexpressing arginase 1 in monocytic cell lineage are affected by lympho - myeloproliferative disorders and disseminated intravascular coagulation.

The results suggest vitamin D increases skin levels of an anti-inflammatory enzyme, arginase - 1.

The group did find CD11c microglia and arginase, an enzyme that breaks down arginine, are highly expressed in regions of the brain involved in memory, in the same regions where neurons had died.

Besides, if the scientists» theory is correct, then the enzyme arginase, unless it's blocked, would still break down the arginine.

The arginase - 2 pathway might be a way to better understand and perhaps find treatments for those conditions, Ginhoux says.

Androgen - regulated expression of arginase 1, arginase 2 and interleukin - 8 in human prostate cancer.

Sustained - release preparations of L - arginine have been suggested as a means of helping to maintain blood levels over time, yet arginase's substantial intestinal and hepatic metabolism of L - arginine to ornithine and urea, combined with L - arginine's use for other functions in the body, significantly lessens the likelihood of optimal improvement in NO production from oral supplements of L - arginine alone.

L - Norvaline works by inhibiting the arginase enzyme thus increasing arginine concentrations, which in turn increase circulating levels of Nitric Oxide, or NO2.