Sentences with phrase «arginine methyltransferase»

(2015) Protein arginine methyltransferase CARM1 attenuates the paraspeckle - mediated nuclear retention of mRNAs containing inverted repeat Alus.

Veland N, Hardikar S, Zhong Y, Gayatri S, Dan J, Strahl BD, Rothbart SB, Bedford MT, Chen T. (2017) The Arginine Methyltransferase PRMT6 Regulates DNA Methylation and Contributes to Global DNA Hypomethylation in Cancer.

PRMT stands for «protein arginine methyltransferase,» and PRMT enzymes facilitate the chemical process of arginine methylation, the fastening of a methyl group (made from one carbon and three hydrogen atoms) to proteins inside cells.

PRMT5 (protein arginine methyltransferase 5) is an enzyme that alters the structure of chromatin to suppress the transcription of genes and the production of proteins.

A protein known as arginine methyltransferase 1 (PRMT1) may be a potential therapeutic target for pancreatic ductal adenocarcinoma (PDAC), the most common type of pancreatic cancer, and one of the most deadliest with a less than 10 percent, five - year survival rate.

This is accomplished by a class of enzymes called protein arginine methyltransferases (PRMTs).