Sentences with phrase «arm of chromosome»

unc - 124 (hs10) was originally isolated as a cold - sensitive (cs) unc mapping to the left arm of chromosome X between dpy - 8 and unc - 10, at approximately 2.4 cM [50]; unc - 7 maps to the right arm of X at +22 cM.

It is located on the long arm of chromosome 15 in the LINGO1 gene, which encodes a protein that has been shown to affect how neurons are formed and signal each other.

Computer analysis of the data, presented at the meeting on 14 October by Andrew Hicks, a scientist at deCODE, revealed that the P arm of chromosome 1 contains a putative disease gene, although the researchers have yet to identify it.

A genome - wide scan performed in 66 high - risk prostate cancer families has provided evidence of linkage to the long arm of chromosome 1 (1q24 - 25).

Only six months ago, a research team led by Bert Vogelstein of Johns Hopkins University in Baltimore and Albert de la Chappelle at the University of Helsinki announced that they had narrowed down the location of the gene to the short arm of chromosome 2.

For example, they identified five double crossovers on one arm of chromosome 2 — fewer than expected.

[2](Some cases are confounded by either a cryptic translocation that is invisible on G - banded chromosome preparations, or a variant translocation involving another chromosome or chromosomes as well as the long arm of chromosomes 9 and 22.

Not exact matches

The researchers discovered that the number of crossovers varied widely not just according to their position along the chromosome arm, but also from chromosome to chromosome.

Unlike crossovers, which are generally distributed over the distal two - thirds of the chromosome arms, the non-crossovers were spread uniformly among the five major chromosome arms.

During meiosis, the cell copies all its chromosomes, pairs them up, and shuffles sections of genetic material between the arms of the paired or homologous chromosomes.

The pivotal molecular markers that define the three tumor clusters — mutational status of the IDH1 and IDH2 genes and loss of chromosome arms 1p and 19q — are already routinely checked in clinical care, Verhaak noted, so implementing the new categories can be done relatively quickly.

The role of aneuploidy — in which entire chromosomes or chromosome arms are added or deleted — has remained largely unstudied.

This means there is a translocation between chromosome 9 and chromosome 22, with breaks happening in region (3), band (4), sub-band (1) of the long arm (q) of chromosome 9 and region (1), band (1), sub-band (2) of the long arm (q) of chromosome 22.

Multiple DNA breaks at either the centromere or the long arm of the mouse Y chromosome cause it to fragment and disappear.

The X chromosomes that will be eliminated line up on the metaphase plate and start to separate — in that their centromeres disjoin and start to be pulled to one pole or the other — but the arms of the Xs fail to separate.

This observation led the team to propose that BRCA1 has an additional role in assisting neurons in orienting: the gene acts on the centromere of DNA — essentially an anchor for the chromosome arms essential in cell replication — to tell the new cell in which direction to grow, providing guidance in developing the brain's organized layers.

The exome sequences of 1,535 Kronos and 1,200 Cadenza mutants have been re-sequenced using Illumina next - generation sequencing, the raw data aligned to the IWGSC Chinese Spring chromosome arm survey sequence, mutations identified, and their effects predicted based on the protein annotation available at the Ensembl Plants archive site.

We have re-sequenced the exome of 1,535 Kronos and 1,200 Cadenza mutants using Illumina next - generation sequencing, aligned this raw data to the IWGSC Chinese Spring chromosome arm survey sequence, identified mutations, and predicted their effects based on the protein annotation available at Ensembl Plants.

About 90 % of solid tumors display whole - chromosome aneuploidy, while many tumors with diploid karyotypes nonetheless harbor segmental or arm - length aneuploidies that also result in significant gene copy number alterations.