Sentences with phrase «around nucleosomes»

In contrast, closed chromatin (heterochromatin) is inaccessible because it's tightly wrapped around nucleosomes.

The genomic DNA of complex organisms is wrapped around nucleosomes and packaged into various conformations that regulate the access of different gene regulatory factors to their target sites.

Although it has not been established that CenH3 alone determines centromere identity, the sequence of a complete centromere should at the least include the entire region that is wound around nucleosomes containing CenH3.

Not exact matches

Nucleosome: Eight histone proteins form the core of a nucleosome, around which the 147 base pairs of a DNA strand aNucleosome: Eight histone proteins form the core of a nucleosome, around which the 147 base pairs of a DNA strand anucleosome, around which the 147 base pairs of a DNA strand are coiled.

In order to fit inside cells, DNA is wrapped around small protein spindles, forming strings of molecules called nucleosomes.

Genomic DNA is packaged into nucleosomes, which are formed by histone proteins that have DNA wrapped around them.

Our genes are packaged into cells by wrapping them around protein structures called nucleosomes.

The ability of PARP1 to control cellular processes is regulated by nucleosomes — the basic unit of DNA packaging, consisting of a segment of DNA wound in sequence around eight histone protein cores, similar to a thread wrapped around a spool.

In this system, the DNA strand, with its genes, is coiled around molecules known as histones, which themselves are assembled into larger entities called nucleosomes.

This is done with the help of nucleosomes, basic units made of proteins around which a segment of DNA is wound.

X-rays and microscopy showed that the primary level of chromatin organization involves 147 bases of DNA spooling around proteins to form particles approximately 11 nanometers (nm) in diameter called nucleosomes.

Because this region covers the entire CenHs - binding region (around 750 kb), the authors [6] postulated that CenH3 - containing and dimethyl - K9 H3 - containing nucleosomes are interspersed and that the position of these nucleosomes is dynamic, so that a population of cells may have the same DNA sequence interacting with both types of nucleosome.

The forward - and reverse - oriented peaks were usually separated by around 180 base pairs, and corresponded to nucleosome boundaries.

Intriguingly, in contrast to the canonical nucleosome (where 147 bp of DNA are wrapped around the histone octamer), only the central 121 bp were visible, suggesting flexible CENP - A nucleosomal ends.

Nucleosome remodelers can work if tethered (33), but given the dynamic nature of DNA interactions observed with most transcription factors, we think that the tethering rather increased the local concentration of the factor around the UASGal site.