Sentences with phrase «arterial cells»

Emerging evidence suggests that that this inflammation can occur in arterial cells (potentially increasing the chance of clogged arteries), skin cells (leading to skin mutations) and reproductive cells (which may be connected to PCOS and other hormone problems).

He and the Vereide Group grow precursors of human arterial cells, build colonies of dendritic cells (cells which can alert the rest of the immune system to the presence of a tumor), and use chick embryos to study the formation of early tissue layers for a possible future in which complex tissues, or even organs, can be grown to replace diseased, wounded, or malfunctioning ones.

The research group developed a protocol around five key growth factors that make the strongest contributions to arterial cell development.

«With this technology, you can test the function of these candidate genes and measure what percentage of cells are generating into our target arterial cells,» says Zhang.

But new techniques developed at the Morgridge Institute for Research and the University of Wisconsin - Madison have produced, for the first time, functional arterial cells at both the quality and scale to be relevant for disease modeling and clinical application.

Some data in animals suggest that peanut lectin may contribute to atherosclerosis by stimulating the growth of smooth muscle and pulmonary arterial cells.

While low HDL levels can increase the risk of cardiovascular disease, particular in obese or insulin resistant individuals, improved HDL cholesterol levels protect against atherosclerosis by removing excess cholesterol from arterial cells.

His work led to the development of a novel method for propagating precursors of human arterial cells that could potentially be used for drug discovery and gives the Vereide Group the ability to model key events during cardiovascular disease.

In arterial cells, these mutations cause inflammation that can clog arteries.

«Interestingly, the ETS factors aren't specific to soon - to - be arterial cells, but rather they are present throughout the embryo,» explained Jason Fish, PhD, a former Gladstone postdoctoral fellow, now at the University of Toronto, who collaborated with the Gladstone team.

«This, in turn, activates another group of proteins, called ETS transcription factors, and it is this signaling relay — from Vegf to MAPKs to ETS factors — that turns on an maintains Dll4 activity, helping the arterial cells grow and gain their cellular identity over time.»

Sphingomyelin is a part of five phospholipids that surround the arterial cell to protect it.