Not exact matches
This laboratory studies aspects of one - carbon metabolism, namely the micronutrients folate and vitamin B12, which serve as substrate and cofactor, respectively, in the methionine cycle and homocysteine, which is a
branch - point metabolite in the methionine cycle and an independent risk factor for cardiovascular
disease (coronary
artery, cerebrovascular and peripheral vascular
disease), cognitive impairment (Alzheimer's
disease) and complications of pregnancy (neural tube defects).
Sulfloraphane has been shown to re-activate Nfr2, a beneficial protein that helps protect
arteries, and found to be absent in
branched or bent
arteries, making them more susceptible to
disease.
Examples of such
diseases in veterinary medicine would include the feline condition now known as FATE where a large blood clot forms in the heart, a small piece of the clot breaks off and then lodges in the aorta (the large
artery that travels the length of the body) right where it
branches to serve the rear legs.
Cardiac ultrasonography of adult worms in the main pulmonary
artery and close portions of the right and left
branches of the
artery enable definitive diagnosis of heartworm
disease.