Cartilage generated in embryos not only regulates skeletal growth until puberty, but also plays a key role in our locomotion as
articular cartilage in our joints.
Not exact matches
If we understood better how the embryo forms
articular cartilage at the
joint, we would be
in a better position to come up with ways of regenerating
cartilage from stem cells to provide improved treatments for
joint injuries and diseases.
For instance,
in articular joints, such as the knee and
cartilage tissue, SnCs often are not cleared from the area after injury, thereby contributing to OA development.
Osteoarthritis is characterized by irreversible loss of
cartilage in articular joints and it can cause severe
joint pain, deformation and incapacitation.
We investigated genes and pathways that mark OA progression
in isolated primary chondrocytes taken from paired intact versus degraded
articular cartilage samples across 38 patients undergoing
joint replacement surgery (discovery cohort: 12 knee OA, replication cohorts: 17 knee OA, 9 hip OA patients).
Acidosis, mostly a nutritional deficiency, may cause both osteoarthritis and rheumatoid arthritis respectively either with erosion and loss of
cartilage, or with inflammation
in articular joints
Cartilage in the joints, called articular cartilage, acts as a shock absorber to cushion the blows of daily wear
Cartilage in the
joints, called
articular cartilage, acts as a shock absorber to cushion the blows of daily wear
cartilage, acts as a shock absorber to cushion the blows of daily wear and tear.
There is a new study showing that
in ballet dancers, it is extreme range of motion rather than hip
joint structure, that leads to hip pathologies that may eventually require surgery such as thinning of
articular cartilage, labral tears and osteoarthritis.
It is a noninflammatory, slowly but inevitably progressive and irreversible syndrome
in which the
articular joint cartilage deteriorates.
More precisely the different
joint conditions grouped under the name of elbow dysplasia include: a ununited anconeal process (failure of union between the anconeal process and the remainder of the ulna beyond 20 weeks of age), the so - called osteochondrosis dissecans of the humeral condyle (failure of ossification of the
articular cartilage covering the humeral condyle, resulting
in an abnormal thickening of the
articular cartilage and separation between this region and the underlying bone), and finally the fragmentation of the coronoid process (
in which the ulnar coronoid process have multiple fragments or most often a single fragment).
This isn't quite as good as
articular cartilage but it relieves the pain
in most dogs and helps to slow or stop further degeneration of the
joint.
The condition is characterized by cracks and flaps
in articular cartilage, which cause inflammation,
joint instability, pain, lameness, and degenerative
joint disease.
Excessive biomechanical loading of the inadequately supported epiphyseal
articular cartilage leads to secondary disturbances
in the nutrition, metabolism, function and viability of the chondrocytes
in the developing
joint surface.