Sentences with phrase «as cell block»

Cast as Cell Block Five Unit Manager Tim McManus, Kinney's hardened performance lent the show both dimension and a certain foundation.

The presented approach uses untethered magnetic micro-robotic coding for precise construction of individual cell - encapsulating hydrogels (such as cell blocks).

Not exact matches

The building block electronic and protonic actual occasions are, in the case of human beings, swept into vastly more complex, Chinese box - like sets of containing societies within which there are social levels that can be identified with cells, others which answer to Aristotle's levels of tissues and organs, and which finally are presided over by what Whitehead refers to as the regnant nexus, a social thread of complex temporal inheritance which, Whitehead suggests, wanders from part to part of the brain, is the seat of conscious direction of the organism as a whole, and answers to what in Plato and Aristotle is called the soul.

It is not a building block in the sense in which entities such as atoms and cells are.

Protein acts as a building block for the body's cells.

Felix Figueroa, 39, of the 2800 block of North Natoma Avenue, had been arrested for a traffic offense and placed into a cell when a surveillance camera inside the lockup filmed Figueroa as he bit one end of the mattress cover, then tore it open and removed the foam inside, police said.

As a teacher I was constantly surprised at the creative ways children would transform the simple playthings in our classroom: a wooden block would become a cell phone, seashells would become tea cups, acorns would become money exchanged at the play store.

One of the most important nutrients for moms is protein, which provides amino acids, known as the building blocks to cells.

Chronic cigarette smoke exposure, as noted in many human cancers, tends to block these cell maturation genes from properly turning on, says Baylin.

«Our study results are the first to argue that we may be able to treat inflammatory bowel disease and protect against transplant rejection not only by blocking TNF alpha as is done currently, but also by stimulating ATG16L1 to prevent early death of cells lining the gut,» says study senior investigator Ken Cadwell, PhD, an associate professor at NYU School of Medicine and NYU Langone Health's Skirball Institute for Biomolecular Medicine.

So far the blocks have been used to build a variety of living 3D shapes that have never before been created on a cell - by - cell basis, such as tubes and solid spheres.

«The enzyme's job is to break down a DNA building block in our cells - to act as «molecular scissors,»» Wu said.

An unknown component of breast milk appears to kill HIV particles and virus - infected cells, as well as blocking HIV transmission in mice with a human immune system.

However, along with this seemingly linear storyline in which retinoids block progesterone's promotion of CK5 + cells, previous work in the lab of CU Cancer Center investigator Peter Kabos, MD, and others shows that breast cancers treated with anti-estrogen drugs like tamoxifen or aromatase inhibitors show an increased population of CK5 + cells — it is as if these therapies remove the roadblock of estrogen - dependent cells, leaving CK5 + cells to proliferate.

The material blocks cell signals, as well, adding an element of risk to tweeting, texting and other mobile activities, as the wearer must break cover to communicate.

DMNT inhibitors, such as 5 - azacytidine and decitabine, boost the interactions of PARP inhibitors to block these proteins even further, causing cancer cell death, the researchers found.

The drug blocks CTLA - 4, a protein receptor on the surface of T - cells that serves as a molecular stop sign, preventing the immune system from going into overdrive.

But their overriding interest in BPTES, says Slusher, was in how it works: by blocking the production of glutamine, an amino acid that acts as a building block of cells and is used frequently by pancreatic cancers to create more cancer cells.

Targeting stromal cells as well as the cancer cells blocks multiple cell signalling pathways that are used by cancer cells to become aggressive.

The studies not only point to the future possibility of specific microRNAs as a treatment for colorectal cancer, but also to the importance of external metabolic events conducted outside the cancer cell in the progression of the disease — factors that could someday be targeted to help slow metastasis, or even block it entirely.

In treating acne, the focus — just as it was decades ago — is on three key factors: preventing dead skin cells from blocking the oil glands, reducing excessive oil production and reducing acne - causing bacteria.

As the wound heals, the gel breaks down into amino acids — the building blocks of proteins — that can be taken up by nearby cells and used for tissue repair, according to MIT neuroscientist Rutledge Ellis - Behnke.

Proton pump inhibitors, or PPIs, work just as their name implies: they block an enzyme system in the stomach's cells essential for pumping out acid.

As cells differentiate, their DNA becomes more tightly packed, and genes that are no longer needed — or those which should not be expressed — are blocked.

«In these diseases of mitochondrial dysfunction, in a sense, it's a false starvation situation for the cell — there are plenty of nutrients, but because there's a block in the mitochondria's normal function, the mitochondria behave as if there's not enough oxygen,» says Chen, who with Birsoy, authored a paper in the journal Cell Reports describing this wcell — there are plenty of nutrients, but because there's a block in the mitochondria's normal function, the mitochondria behave as if there's not enough oxygen,» says Chen, who with Birsoy, authored a paper in the journal Cell Reports describing this wCell Reports describing this work.

A separate analysis of 3BNC117 by Ching - Lan Lu et al. reveals that the antibody not only blocks infection of new cells, but accelerates the clearance of infected cells as well.

And NCATS has had some, such as the discovery that an existing antihistamine, chlorcyclizine, blocks the ability of the hepatitis C virus to infect cells.

Scientists have uncovered the mechanism that translates stress such as exposure to extreme temperature into blocked cell growth.

Wyrick and WSU colleagues Peng Mao, Michael Smerdon and Steven Roberts irradiated yeast cells and looked for patterns of damage at the level of individual base pairs, the DNA building blocks whose order serves as an organism's blueprint.

However, immune cells may be blocked by inhibitory molecules, which serve as checkpoints to alleviate or «turn off» the immune system response, Gu explained.

«Although, both ketamine and memantine have similar actions when nerve cells are active, under resting conditions, memantine is less effective in blocking nerve cell communication compared to ketamine, This fundamental difference in their action could explain why memantine has not been effective as a rapid antidepressant» said Dr. Monteggia, who holds the Ginny and John Eulich Professorship in Autism Spectrum Disorders.

At that point, physicians switch to other drugs, such as enzalutamide, which block testosterone's ability to bind to receptors within prostate cancer cells.

The researchers tested two anti-CK2 drugs for their ability to stimulate the production of new brown fat in mice: a new small - molecule CK2 - blocker called silmitasertib (CX - 4945), which is already in clinical trials as a cancer therapeutic; and a more precise next - generation antisense oligonucleotide (ASO) drug developed in collaboration with Isis Pharmaceuticals, which eliminates CK2 by blocking the RNA instructions cells use to produce it.

As Louis H. Miller, Head of Malaria Cell Biology Section at the National Institutes of Health notes, «The findings on the liver receptor EphA2 for malaria parasite sporozoite invasion of liver cells is a critically important advance and might allow us to devise new strategies to block parasite infection.»

When they inserted a fluorescent reporter protein in this virus - like shell, their test became capable of high - speed screening to see which drugs blocked the entry of Ebola - like viral particles into cells as measured by fluorescence.

Cells take a number of complicated steps to translate their sequence of basic DNA building blocks into proteins, which then act as workhorses to carry out the vital functions of life.

In this case, the stumbling block is that the semiconductor materials in solar cells, such as silicon, become conductive and generate energy only in response to photons at certain energy levels.

Geschwind, a professor in the Russell H. Morgan Department of Radiology and Radiological Science at the Johns Hopkins University School of Medicine and its Kimmel Cancer Center, and others at Johns Hopkins have been studying the experimental drug as a cancer treatment for over a decade because of its ability to block a key metabolic pathway of cancer cells.

To block this signal, recent clinical studies have focused on inhibiting the activation of the B - cell receptor as a treatment for non-Hodgkin lymphoma patients, but with variable success.

Additionally, ethylene and ethanol could serve as the building blocks for a range of consumer goods, and CO2 - derived formic acid could be used by the pharmaceutical industry or as a fuel in fuel cells.

The researchers confirmed Olig2's role in promoting motor neuron formation by increasing or blocking the function of Olig2 in the spinal cords of developing mouse and chicken embryos, as well as during motor neuron formation in mouse embryonic stem cells.

The fungus makes the chelator and produces hydrogen peroxide from oxygen, and together they start to digest the cell wall into the sugar found in the basic building block of wood, glucose, which the fungus can use as food.

The hope is the technique could be used to unpick the role of proteins in many complex processes, such as the consolidation of memories, or be used to block the interactions between proteins within cells to help illuminate the processes that underpin disease.

Biologic drugs that block TNF from signalling to cells have revolutionized treatment for autoimmune conditions such as rheumatoid arthritis over the past decade, says Fugger.

The MIT team hypothesized that natural shape - shifters such as yeast, bacteria, and other microbial cells might be used as building blocks to construct moisture - responsive fabrics.

Lengner cautions, however, that rapamycin can not be used as a stand - in for calorie restriction, as it would linger and continue to block mTOR activation even following injury, hindering the ability of the reserve stem cells to spring into action and regenerate intestinal tissue.

A better approach, Monje said, would be to develop drugs that specifically block the tumor - stimulating activities of neuroligin - 3, such as a drug that stops the protein from being secreted into the area around the cancer cells.

Once they identified this pathway, Hanks and colleagues conducted laboratory tests of a molecule that blocks melanoma cells from going stealth, enabling the immune system to mount a direct attack while also enhancing the function of current immunotherapies such as pembrolizumab and nivolumab.

The researchers performed lab experiments on cells derived from a cervical cancer and found that when DOHH is blocked, a protein known as eIF5A fails to mature.

Functional expression of the cDNAs in cultured mammalian cells generated receptors displaying alpha - amino -3-hydroxy-5-methyl-4-isoxazole propionic acid (AMPA)- selective binding pharmacology (AMPA = quisqualate greater than glutamate greater than kainate) as well as cation channels gated by glutamate, AMPA, and kainate and blocked by 6,7 - dinitroquinoxaline -2,3-dione (CNQX).