Sentences with phrase «as tyrosinase»

[5] Quercetin as a tyrosinase inhibitor: Inhibitory activity, conformational change and mechanism.

Demonstrating Cpf1's noticeable specificity, another research team from the same IBS Center succeeded in bringing Cpf1 RNP - mediated mutations into mouse embryos: The researchers targeted Foxn1 (a transcription factor that regulates the immune system, including the growth of skin hairs), as well as Tyrosinase (an enzyme that catalyzes the production of melanin, a natural pigment that determines the color of skin).

Not exact matches

As a whole, a great deal of compounds exhibiting tyrosinase inhibitory capacities has been isolated on land.

Moreover, flavonoids with a 4 - substituted resorcinol unit at ring B were regarded as potent tyrosinase inhibitors.

Considering the medical and cosmetic sector, a great number of researches focused on the isolation of tyrosinase inhibitors from both terrestrial and marine environment belonging to diverse chemical classes such as phenolics (flavonoids, lignans, stilbenes, coumarins, arylbenzofurans, tannins), megastigmane - type (nor - isoprenoid), terpenes, cyclic peptides, alkaloids and steroids.

However, potent compounds from the marine environment, especially extreme surroundings such as hydrothermal vents or arctic regions only await to be unveiled which undoubtedly hold promises in the discovery of tyrosinase inhibition, thus opening new perspective for treatment of skin disorders as well as neurodegeneration related diseases.

Previous studies have shown that flavonoids have the capacity of chelating the active site as well as acting as cofactor or substrate of tyrosinase, thus inhibiting its effect.

Compounds belonging to the terpenes group revealed tyrosinase inhibitory activities due to different aspects including the position and relative configuration of the hydroxyl groups as well as the nature and numbers of sugar units as in cycloartane glycosides.

A skin - lightening ingredient that works by inhibiting the activity of tyrosinase, by acting as a melanocyte cytotoxic inhibitor, and by increasing the cytotoxicity of melanocytes.

marine algae as a natural source of tyrosinase inhibitor.