Certain bacterial species, referred to as «secondary colonizers,» secrete a self - produced matrix referred to
as a biofilm in which multiple bacterial species reside in structured community.»
Not exact matches
The finding could explain how some bacteria, such
as Pseudomonas aeruginosa (P. aeruginosa), are able to thrive
in oxygen - poor environments like
biofilms and resist antibiotics.
That bacterial
biofilms exhibit different behavior
in space versus on Earth is critical information
as NASA strives to keep astronauts healthy and safe during future long - duration space missions.
«
Biofilms were rampant on the Mir space station and continue to be a challenge on the International Space Station, but we still don't really know what role gravity plays in their growth and development,» said Cynthia Collins, Ph.D., principal investigator for the study and assistant professor in the Department of Chemical and Biological Engineering at the Center for Biotechnology and Interdisciplinary Studies at the Rensselaer Polytechnic Institute in Troy, N.Y. «Before we start sending astronauts to Mars or embarking on other long - term spaceflight missions, we need to be as certain as possible that we have eliminated or significantly reduced the risk that biofilms pose to the human crew and their equipment
Biofilms were rampant on the Mir space station and continue to be a challenge on the International Space Station, but we still don't really know what role gravity plays
in their growth and development,» said Cynthia Collins, Ph.D., principal investigator for the study and assistant professor
in the Department of Chemical and Biological Engineering at the Center for Biotechnology and Interdisciplinary Studies at the Rensselaer Polytechnic Institute
in Troy, N.Y. «Before we start sending astronauts to Mars or embarking on other long - term spaceflight missions, we need to be
as certain
as possible that we have eliminated or significantly reduced the risk that
biofilms pose to the human crew and their equipment
biofilms pose to the human crew and their equipment.»
As these resilient microbes thrive, they can group together on a surface — like a wound or a medical device — and encase themselves in a slimy protective layer known as a biofil
As these resilient microbes thrive, they can group together on a surface — like a wound or a medical device — and encase themselves
in a slimy protective layer known
as a biofil
as a
biofilm.
Microorganisms like bacteria often are found attached to surfaces living
in communities known
as biofilms.
Bacteria living
in a
biofilm can be 10 to 1,000 times
as hard to kill
as their free - floating counterparts.
Colonies of bacteria called
biofilms live longer
in Mars - like waters — especially if they were dried out first,
as they would be after hitching a ride through space
In earlier work, these investigators showed —
as numerous others had done — that the messenger molecule, cyclic - di - GMP (c - di - GMP) promotes
biofilm formation when such surfaces are present, said principal investigator Vincent T. Lee, Associate Professor, Department of Cell Biology and Molecular Genetics, University of Maryland, College Park.
The researchers» report appears
in the journal ACS Synthetic Biology and describes development of this new type of E. coli that can even kill off slimy groups of bacteria called
biofilms that are responsible for many hard - to - treat infections, such
as those that take hold
in the lungs, the bladder and on implanted medical devices.
First author Minyoung Kevin Kim, a graduate student
in Princeton's Department of Chemistry, built experimental devices that mimicked common environments
in which bacteria are subjected to the flow of liquids such
as wastewater or bodily fluids: the interior surfaces of pipes, the crevices found
in the lining of the intestines, and surfaces coated with
biofilms, among others.
Instead, they scupper what is known
as quorum sensing, i.e, a system used by bacteria to communicate with the help of messenger substances that results
in the formation of
biofilms.
The finding could help doctors tackle infections
in which
biofilms are common, such
as cystic fibrosis
Dental plaque may be the best - known example of a
biofilm, but these slimy aggregates of bacteria also play major roles
in such chronic infections
as those
in the urinary tract or
in the lungs
in cystic fibrosis patients.
As a result, the activities of the antioxidant enzymes glutathione peroxidase and catalase were restored, ROS levels decreased, and the bacterial
biofilm disintegrated
in the wound — all of which resulted
in the development of healthier wound tissue and led to wound healing.
Subsequently, the investigators found that the
biofilm was forming more quickly and to a greater degree
in these ArsS - deficient strains,
as compared to other mutants.
«But the organisms that we detected
as abundant
in these
biofilms appear to have characteristics that could be of interest because they are related to some bacteria that are opportunistic pathogens that could pose a threat, especially to immunocompromised hospital patients»
Live (green) versus dead (red) bacteria «illustrate the effective survival of bacteria growing
as attached
biofilms, with beauty visible
in their growth,» Joubert writes.
Bassler says that
in some instances — such
as in dental
biofilms,
in which some 600 species may be growing at a time — AI - 2 is necessary for collective or cooperative behavior.
Each year roughly 500,000 people
in the United States die of
biofilm - associated infections, nearly
as many
as those who die of cancer.
Since
biofilms in chronic wounds are built up by multiple species of bacteria, it is important to attack
as many
as possible at the same time, Wolcott says.
Here, there aren't
as many bacteria
in thick
biofilms, and viruses swarm the microbes (
as seen
in this image from an electron microscope), picking them off one by one.
Opportunistic premise plumbing pathogens, such
as the bacteria that causes Legionnaire's disease, Legionella pneumophila, can thrive
in low - nutrient conditions and grow
as biofilms on the inner surfaces of pipes.
In many cases, these secreted compounds may enable a
biofilm,
as a collective, to degrade complex polymers — including host tissues — that otherwise would be inaccessible [9, 12].
Modern
biofilms grown on microscope slides
in pond water were allowed to desiccate for 7 days and 2.5 milligrams were pressed into a KBr pellet
as above.
Numerous studies on postmortem brains have found evidence of infection, such
as biofilms,
in the same regions
as Alzheimer's neurodegeneration — namely, the hippocampus and temporal lobe (1).
Biocellion is being used to model a variety of biological system behaviors, such
as biofilm formation and wrinkling, microbial growth dynamics
in complex soil structure, brain tumor growth and invasion, formation of complex bacterial colonies, and changes
in blood vessels and skin cells.
Another focus
in the lab is exploring the use of engineered bacterial
biofilms as materials for the selective removal or purification of various soluble components,
as might be relevant for water decontamination.
In addition, we compared the relative biofilm capability of the representative strains as indicators of their survival and persistence in the environment and K7 showed enhanced biofilm forming capabilities (p = 0.004
In addition, we compared the relative
biofilm capability of the representative strains
as indicators of their survival and persistence
in the environment and K7 showed enhanced biofilm forming capabilities (p = 0.004
in the environment and K7 showed enhanced
biofilm forming capabilities (p = 0.004).
Eating sugary and starchy foods, drinking tea, coffee, and soda leads to an altered pH
in the mouth - > certain strains of bacteria to proliferate - > bacteria form
biofilms to protect themselves from mechanical removal such
as is done through the flow of saliva or brushing teeth - >
biofilms cause a buildup of plaque on the teeth from bacteria
in the mouth.
Because of the number of relapses
in both bacterial and yeast issues, alternative treatments
as these
biofilm agents provide are needed to complete eradication.
They have bacteria
in their mouth that form
biofilms of tartar and plaque, just
as we do.
The therapeutic benefits of Zymox Brushless products include restoring the oral balance to replenish what is missing
in saliva, inhibiting the odor - causing bacteria,
as well
as the removal of plaque
biofilm.