Sentences with phrase «as a biomarker of»
Human sperm may hold the potential to serve as biomarkers of the future health of newborn infants, according to a new study by a Wayne State University School of Medicine research team.
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The third researcher, Daniel Conklin of the University of Louisville, tracked biomarkers of exposure to new and emerging tobacco products as well as biomarkers of cardiovascular harm and injury.
«Our results, and methods, could have implications for the analysis of endogenous and exogeneous compounds in the exhaled breath as biomarkers of systemic and lung diseases, as well as in development of new approaches to study human exposure to airborne contamination.»
The blood samples were analyzed to measure hormone and lipid levels, as well as biomarkers of insulin resistance and inflammation.
During the webinar, our expert panel of researchers will discuss: • Strategies and technologies for successful cancer biomarker discovery through robust detection and analysis of miRNAs in biofluids • Research into analytic and biological variables that impact miRNA measurements in serum and plasma from the clinical pathologist's point of view • The novel application of miRNAs in serum as biomarkers of aging and chronic disease • The answers to questions submitted by the live, online viewers.
Major focus areas include human genome interpretation and genetic dissection of novel rare diseases, predictive genomic signatures of response to therapy — especially cancer therapy, and novel sequencing - based assays as biomarkers of disease.
Also featured in the story were two researchers at the Wyss Institute for Biologically Inspired Engineering at Harvard, Donald Ingber (for his «gut - on - a-chip» model of intestinal inflammation and bacterial overload) and Pam Silver (for her her work on engineering bacteria as biomarkers of inflammation).
Strong infrared rays from an extrasolar planet is considered as a biomarker of plants.
Hypomineralized teeth as biomarkers of exposure to endocrine disruptors.
The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.
It's potential as a biomarker of disease and an early objective marker of treatment response is genuine but still to be realized.Resting - state functional magnetic resonance imaging has made some strides in the clinical realm but significant advances are required before it can be used in a meaningful way at the single - patient level.
miR - 9551 also has potential as a biomarker of resistance in different nematode species.
Further innovation arises from the effective use of brain imaging as a biomarker of disease progression.
The SFN - NAC is not the only metabolite present in urine and, as along with DIM, could be used as biomarker of the consumption of cruciferous vegetables.
In it, they state plainly that «grip strength might act as a biomarker of ageing across the life course.»
Blunted cortisol levels, often termed hypocortisolism, are increasingly recognized as a biomarker of chronic stress and may result from downregulation of the HPA axis subsequent to chronic cortisol elevations.18 - 20 There are a few possible interpretations for the normalization of these diurnal rhythms observed with the intervention.
Not exact matches
As a Genentech spokesperson told me at the time: «Despite looking at hundreds of potential predictive biomarkers, we do not currently have a way to predict who is most likely to respond to Avastin and who is not.»
Peripheral inflammatory responses may, then, serve as biomarkers and thus serve as targets of immune - based therapies for depression.
Support a multi-year effort led by world - class scientists to develop a blood test for earlier detection of breast cancer when survival rates are the highest, known as the EIF Breast Cancer Biomarker Discovery Project.
Objective To determine the types and frequency of rice and rice - containing products consumed by infants in the first year of life and the association with As biomarker concentrations.
While we are unaware of any prior studies relating As biomarker concentrations to rice intake among infants, associations have been observed in pregnant women in our cohort, 19 children in the National Health and Nutrition Examination Survey, 16,18 and multiple studies of adults.11 - 15
Intake of rice early in childhood has not been well characterized in the United States, and there are only limited data from other regions of the world.5, 6 Moreover, biomarker concentrations of As among infants consuming rice are virtually unknown.
«This phase III trial will be noteworthy for being the first prostate cancer trial to assess a biomarker, namely AR - V7 in circulating tumour cells, as a predictor of response at the same time as testing the efficacy of the drug,» Prof Taplin will conclude.
An analysis of the results identified four of the proteins as potential biomarkers.
The focus of those hopes is the liquid biopsy: a test that could detect and analyze a solid tumor from biomarkers in the bloodstream or other easily sampled body fluids, such as saliva.
«It can handle multiple biomarker technologies simultaneously, such as complex flow cytometry, next - generation sequencing, immunosequencing, epigenetic profiling, and other types of asssys measuring biological variation as well,» says Marshall.
Recent advances in detection, as well as the comprehensive power of clusters of biomarkers, or biomarker signatures, are making the brain more accessible and neurological diseases more treatable.
The selected stationary phases fully leverage the separation power of sub-2-µm particle technology, delivering the efficiency and selectivity required for complex separations such as discovery of low - abundance species, peptide mapping, protein identification, and biomarker discovery.
As the number of biomarkers increases and the types of biomarkers expand, the amount of information that researchers must organize becomes overwhelming.
For researchers using mouse models to study a variety of cancers, including lymphoma, melanoma, breast, and prostate cancers as well as autoimmune and infectious diseases, the panel facilitates a highly sensitive and high - throughput investigation of biomarkers associated with disease progression.
In the process, they might identify a planet's surface features — such as oceans, continents, ice caps and even cloudbanks — and detect the presence of biomarkers like oxygen, methane and water.
Recently, DNA shed from tumor cells has been identified as a noninvasive method of screening biomarkers for the early diagnosis and prognosis of cancer.
Larger biomarker signatures can be detected with technology from CDI Laboratories, which offers microarrays of functional human proteins (over 20,000 on a single array) to test the antibodies present in human liquid biopsy samples, such as blood, serum, plasma, CSF, or tissue lysates.
Biomarker data management platforms become even more essential as different types of biomarkers are analyzed together, such as proteins and miRNAs.
«We can see a single femtogram per mL of a biomarker, which is sensitive enough to detect biomarkers in saliva and breath condensate as well.»
Each reservoir has specific amounts of different biomarkers, so oil biomarkers serve as identifiers much like human fingerprints.
The researchers also found that using physiological biomarkers, such as hormones from droppings, is an effective way of evaluating the impact of ecological and demographic factors on animal populations.
As Quintela says, if these data are confirmed, this genetic variant - present in 15 % of Caucasian people - could be used as a reliable biomarker in personalised medicine to select the best suited candidates to receive this druAs Quintela says, if these data are confirmed, this genetic variant - present in 15 % of Caucasian people - could be used as a reliable biomarker in personalised medicine to select the best suited candidates to receive this druas a reliable biomarker in personalised medicine to select the best suited candidates to receive this drug.
«With this new biomarker, we are measuring the brain's default state for processing sound and how that has changed as a result of a head injury,» Kraus said.
This new study of non-military, civilian trauma patients visiting the emergency department builds on recent research conducted by Dr. Samadani, supported through the Cohen Veterans Center, which found that the use of this novel eye - tracking technology could reveal edema, or swelling, in the brain as a potential biomarker for assessing brain function and monitoring recovery in people with head injuries.
«We hope that our work will provide the basis for a larger study of patient samples that may ultimately identify biomarkers that can be used as surrogate markers to determine the benefit of therapeutic interventions in diagnosed but asymptomatic HD patients to prevent or delay disease onset.»
About 15 to 20 % of breast cancers are classified as «triple negative,» so called because these tumors do not express three key proteins that are biomarkers and / or drug targets for breast cancer: the estrogen receptor, the progesterone receptor, and HER2 (a member of the epidermal growth factor receptor family).
The foundation's latest gift will fund the purchase of the Simoa technology and support Dr. de Leon's research to study its use as a potential biomarker for TBI.
«Adding these two biomarkers provided statistically significant improvement for all early stage cancer versus healthy controls as well as other subcohorts when used with the current gold standard biomarker, CA 19 - 9,» said Ann Killary, Ph.D., professor of Translational Molecular Pathology.
«This finding,» Villanueva said «opens the door to developing new biomarkers and new therapeutic strategies exploiting these characteristics of exosomes in breast tumors, and other tumors such as ovarian and endometrial cancer among others.»
In the future, doctors could thus use Gab2 as a biomarker and infer the course of the disease by measuring Gab2 levels.
«Starting with our cell model that mimics human pancreatic cancer progression, we identified released proteins, then tested and validated a subset of these proteins as potential plasma biomarkers of this cancer,» Zaret said.
While the study included a large number of vascular risk factors, no information was available on individual biomarkers, or migraine specifics such as the presence or absence of migraine aura.
As not all cases of Barrett esophagus become malignant, it is important for the treating physician to know whether there are reliable indicators (so - called biomarkers) which allow the estimation of a tumor development in the still benign tissue.
«This is one of the first steps into identifying cholesterol as a potential biomarker for canine osteosarcoma,» said Haley Leeper, a veterinary oncology resident at the OSU College of Veterinary Medicine.