Sentences with phrase «as a positive control for»

1H7 was raised from recombinant full - length AS, as was 9E4, a mAb previously used successfully to target AS in PDGF - AS mice [20] and was therefore included in the new study as a positive control for the 3 novel mAbs.

As a positive control for total inhibition, 50 µM suramin - treatment for 6 h was used (Figure 5, C +).

Whole genome expression data of livers of wildtype and PPARα − / − mice fasted for 24 h served as positive control for PPARα - dependent gene regulation.

Not exact matches

We were happy that things were looking positive, but at 5 pm I was told that she was not to have any more breastfeeds for the time being because she might need another transfusion and she needed to spend as much time as possible under the lamps to keep the jaundice under control.

If your child loves downloading episodes of favorite TV shows from iTunes, this purchase - on - presentation coupon lets you give them as a gift or a reward for positive behavior — and, unlike a pre-paid gift certificate, gives you control over what gets downloaded and when.

I felt out of control and unable to go on if I was disconnected from him for a contraction, and luckily that was very rare, because our arms and eyes were locked and he whispered positive affirmations of my beauty and strength as a broke between contractions and braced himself for my open, groaning mouth and face buried in his chest through each overwhelming vibration.

The positive, declarative statement will help them to develop a positive self - image and set the foundation for self - control as they grow up believing that, yes, they are good and gentle little people!

In the infant - toddler years, these take the form of sensitive - responsiveness, which is known to foster attachment security, 1 and mutually - positive parent - child relations, which themselves promote child cooperation, compliance and conscience development.2 In the preschool through adolescent years, authoritative (vs. neglectful) parenting that mixes high levels of warmth and acceptance with firm control and clear and consistent limit - setting fosters prosocial orientation, achievement striving, and positive peer relations.3, 4,5 Across childhood and adolescence, then, parenting that treats the child as an individual, respecting developmentally - appropriate needs for autonomy, and which is not psychologically intrusive / manipulative or harshly coercive contributes to the development of the kinds of psychological and behavioural «outcomes» valued in the western world.

However using positive discipline, which identifies boundaries and helps children control and modify their own behavior, can be valuable for parents as well as children.

Although regression analyses indicated an IQ difference even after controlling for social class and the mother's education, the decision to breastfeed may reflect intellectual and other parental factors, such as parenting skills and positive health attitudes that may be responsible for the higher IQ scores.

In Schenectady, he escorted the federal railroad administrator to inspect train tracks that he believes should be eligible for federal funds to install the safety feature known as Positive Train Control.

For 5 months, every comment submitted by a user randomly received an «up» vote (positive); a «down» vote (negative); or as a control, no vote at all.

The meetings served as a control for the fact that participants in the problem - solving therapy arm were seen in person on a weekly basis, and social contact of this nature can have a positive effect on mood.

The research team found that IED - diagnosed group was more than twice as likely to test positive for toxoplasmosis exposure (22 percent) as measured by a blood test, compared to the healthy control group (9 percent).

Research from Queen Mary University of London reveals positive aspects of working life — such as high levels of control at work, good support from supervisors and colleagues, and feeling cared for — support higher levels of wellbeing among Britain's workers.

One reaction serves as a positive control to amplify a portion of the tubulin gene found in all plants, and the other assays for genetic modification.

Negative controls including the secondary antibody alone and uninfected monkey tissue were used, as was an ex vivo section of infected macaque brain tissue [43] for the positive control.

For models, such as SMR, where the distribution of the model parameters is unknown, permutation test and stability selection are typically used to control for false positivFor models, such as SMR, where the distribution of the model parameters is unknown, permutation test and stability selection are typically used to control for false positivfor false positives.

Using serial dilutions of a cloned fragment of XMRV gag as a positive control, the nested PCR assay could reliably detect at least 3 copies of DNA per reaction, even when spiked into genomic DNA prepared either from 293FT cells or donor PBMCs previously validated to be negative for XMRV.

Susan Amara, USA - «Regulation of transporter function and trafficking by amphetamines, Structure - function relationships in excitatory amino acid transporters (EAATs), Modulation of dopamine transporters (DAT) by GPCRs, Genetics and functional analyses of human trace amine receptors» Tom I. Bonner, USA (Past Core Member)- Genomics, G protein coupled receptors Michel Bouvier, Canada - Molecular Pharmacology of G protein - Coupled Receptors; Molecular mechanisms controlling the selectivity and efficacy of GPCR signalling Thomas Burris, USA - Nuclear Receptor Pharmacology and Drug Discovery William A. Catterall, USA (Past Core Member)- The Molecular Basis of Electrical Excitability Steven Charlton, UK - Molecular Pharmacology and Drug Discovery Moses Chao, USA - Mechanisms of Neurotophin Receptor Signaling Mark Coles, UK - Cellular differentiation, human embryonic stem cells, stromal cells, haematopoietic stem cells, organogenesis, lymphoid microenvironments, develomental immunology Steven L. Colletti, USA Graham L Collingridge, UK Philippe Delerive, France - Metabolic Research (diabetes, obesity, non-alcoholic fatty liver, cardio - vascular diseases, nuclear hormone receptor, GPCRs, kinases) Sir Colin T. Dollery, UK (Founder and Past Core Member) Richard M. Eglen, UK Stephen M. Foord, UK David Gloriam, Denmark - GPCRs, databases, computational drug design, orphan recetpors Gillian Gray, UK Debbie Hay, New Zealand - G protein - coupled receptors, peptide receptors, CGRP, Amylin, Adrenomedullin, Migraine, Diabetes / obesity Allyn C. Howlett, USA Franz Hofmann, Germany - Voltage dependent calcium channels and the positive inotropic effect of beta adrenergic stimulation; cardiovascular function of cGMP protein kinase Yu Huang, Hong Kong - Endothelial and Metabolic Dysfunction, and Novel Biomarkers in Diabetes, Hypertension, Dyslipidemia and Estrogen Deficiency, Endothelium - derived Contracting Factors in the Regulation of Vascular Tone, Adipose Tissue Regulation of Vascular Function in Obesity, Diabetes and Hypertension, Pharmacological Characterization of New Anti-diabetic and Anti-hypertensive Drugs, Hypotensive and antioxidant Actions of Biologically Active Components of Traditional Chinese Herbs and Natural Plants including Polypehnols and Ginsenosides Adriaan P. IJzerman, The Netherlands - G protein - coupled receptors; allosteric modulation; binding kinetics Michael F Jarvis, USA - Purines and Purinergic Receptors and Voltage-gated ion channel (sodium and calcium) pharmacology Pain mechanisms Research Reproducibility Bong - Kiun Kaang, Korea - G protein - coupled receptors; Glutamate receptors; Neuropsychiatric disorders Eamonn Kelly, Prof, UK - Molecular Pharmacology of G protein - coupled receptors, in particular opioid receptors, regulation of GPCRs by kinasis and arrestins Terry Kenakin, USA - Drug receptor pharmacodynamics, receptor theory Janos Kiss, Hungary - Neurodegenerative disorders, Alzheimer's disease Stefan Knapp, Germany - Rational design of highly selective inhibitors (so call chemical probes) targeting protein kinases as well as protein interaction inhibitors of the bromodomain family Andrew Knight, UK Chris Langmead, Australia - Drug discovery, GPCRs, neuroscience and analytical pharmacology Vincent Laudet, France (Past Core Member)- Evolution of the Nuclear Receptor / Ligand couple Margaret R. MacLean, UK - Serotonin, endothelin, estrogen, microRNAs and pulmonary hyperten Neil Marrion, UK - Calcium - activated potassium channels, neuronal excitability Fiona Marshall, UK - GPCR molecular pharmacology, structure and drug discovery Alistair Mathie, UK - Ion channel structure, function and regulation, pain and the nervous system Ian McGrath, UK - Adrenoceptors; autonomic transmission; vascular pharmacology Graeme Milligan, UK - Structure, function and regulation of G protein - coupled receptors Richard Neubig, USA (Past Core Member)- G protein signaling; academic drug discovery Stefan Offermanns, Germany - G protein - coupled receptors, vascular / metabolic signaling Richard Olsen, USA - Structure and function of GABA - A receptors; mode of action of GABAergic drugs including general anesthetics and ethanol Jean - Philippe Pin, France (Past Core Member)- GPCR - mGLuR - GABAB - structure function relationship - pharmacology - biophysics Helgi Schiöth, Sweden David Searls, USA - Bioinformatics Graeme Semple, USA - GPCR Medicinal Chemistry Patrick M. Sexton, Australia - G protein - coupled receptors Roland Staal, USA - Microglia and neuroinflammation in neuropathic pain and neurological disorders Bart Staels, France - Nuclear receptor signaling in metabolic and cardiovascular diseases Katerina Tiligada, Greece - Immunopharmacology, histamine, histamine receptors, hypersensitivity, drug allergy, inflammation Georg Terstappen, Germany - Drug discovery for neurodegenerative diseases with a focus on AD Mary Vore, USA - Activity and regulation of expression and function of the ATP - binding cassette (ABC) transporters

B. Semi-quantitative β - actin PCR results for PBMC DNA specimens above in lanes 1 - 14; lane 15, water control; lanes 16 - 19, 10-fold dilutions of blood donor PBMC DNA starting at 0.1 ug as a positive assay control.

The β - catenin / TCF binding site for c - MYC was amplified as a positive control, and the genomic sequence for β - actin was amplified as a negative control.

Make sure to always perform the negative, eccentric part of the lift in a very slow and controlled manner, and allow for an equally slow and smooth transition to the positive, or concentric portion, but then lift the weight up explosively to recruit as many muscle fibers as possible.

But not being controlled by your limitations is positive for you as an individual and will benefit your relationship as well.

For years it has been touted as having positive health benefits for increasing productivity in brain function, lowering troublesome blood pressure, and even controlling blood sugar levels while keeping your blood vessels strong and improving circulatiFor years it has been touted as having positive health benefits for increasing productivity in brain function, lowering troublesome blood pressure, and even controlling blood sugar levels while keeping your blood vessels strong and improving circulatifor increasing productivity in brain function, lowering troublesome blood pressure, and even controlling blood sugar levels while keeping your blood vessels strong and improving circulation.

These results are encouraging news for individuals with or at risk for type 2 diabetes since they indicate that simple diet changes, such as the inclusion of beans, can have a positive impact on blood sugar control.

In order for the Centers for Disease Control (CDC) to recognize a Lyme case for surveillance purposes, there must be «objective» findings, such as positive blood tests, Bell's palsy or joint swelling (even though Lyme blood tests are unreliable and the CDC's accepted «objective» indicators are not common).

An additional 43 patients positive for TPO antibodies or with hypoechogenicity on ultrasound served as a control group.

Although certain contraceptive pills can have positive effects on women with a tendency for acne, as a dermatologist I don't usually recommend starting the contraceptive pill as a way of controlling your acne.

Although they have been reported as helpful for menopausal symptoms such as flushing, to my knowledge there are not well controlled clinical studies to investigate whether long - term supplementation has positive effects on our skin quality.

It has been suggested that the positive associations reported in case - control studies may have resulted from recall bias or confounding by factors such as smoking.19, 34 However, because we observed an association between coffee and risk of MI among carriers of the * 1F allele, and not among those homozygous for the * 1A allele, the associations between coffee and MI are unlikely due to recall bias or residual confounding.

In contrast, ESSA defines four levels of «evidence - based» practices: «strong,» with at least one well - designed and well - implemented experimental study with a statistically significant, positive effect; «moderate,» with at least one well - designed and well - implemented quasi-experimental study such as a matched - comparison group; «promising,» with at least one well - designed and well - implemented correlational study with statistical controls for selection bias.

In the first we looked only at the association of the Positive State Policy Index and teachers «ratings of the principal «s instructional leadership, controlling for two key school characteristics (building level, coded as elementary or secondary; and the percentage of students in poverty, or eligible for free and reduced - price lunch).

Others realized that if video cameras were used as tools for control, they could profoundly damage teacher morale and decrease the likelihood of any positive change occurring in schools.

So proponents claiming the mantle of «education reform» have been quick to jump on the one - sided election results as proof - positive of widespread voter support for their ideas, which include competitive charter schools, vouchers to transfer public education money into private hands, and harsh accountability measures to punish schools and teachers for the circumstances they have very little control over.

From participation in cooperative learning activities, students with emotional disorders can (1) learn from positive role models how to control emotions and behave appropriately in group settings; (2) develop sensitivity to the needs of others and understand people «as individuals rather than as stereotypical members of a particular group»; 14 (3) increase their ability for self - direction; (4) increase their interest in learning; and (5) gain an increase in self - esteem.15 Likewise, students who are not disabled are given the opportunity to become more understanding and accepting of students who are emotionally behaviorally disordered.

Therefore, a well - resourced classroom is critical for developing positive qualities such as perseverance, internal locus of control, and high self - efficacy that prepare students for better academic performance and life success.

The State School Board's recent decision to eliminate physical education, arts and health courses as core statewide requirements for middle - school students is seen as a way to give local districts more flexibility in designing curriculum, which is a positive development in the context of allowing more local control over education policy.

D.C. Merrill in his 1995 article «Tutoring: Guided Learning by Doing» reports that surveys of students who were tutored in reading have shown positive results for students» self confidence as readers, motivation to read, and view of their control over their reading abilities.»

Award - winning psychologist and educator Thomas Lickona offers more than one hundred practical strategies that parents and schools have used to help kids build strong personal character as the foundation for a purposeful, productive, and fulfilling life.Succeeding in life takes character, and Lickona shows how irresponsible and destructive behavior can invariably be traced to the absence of good character and its ten essential qualities: wisdom, justice, fortitude, self - control, love, a positive attitude, hard work, integrity, gratitude, and humility.

The more positive and almost aggressive your inputs the better, as this keeps things loaded up, but it feels like a big car to try and control... particularly when there are also bumps and cambers constantly distracting it from your hoped - for trajectory.

Although a car prone to unexpected oversteer would be described as having poor roadholding, the ability for deliberate oversteer to be easily controlled is regarded as a positive handling attribute.

The system features a new braking module delivering more discreet interventions and provides improved functionality for existing features such as ABS, Dynamic Stability Control (DSC), Electronic Brakeforce Distribution (EBD), Traction Control (TC) and Positive Torque Control (PTC) as well as the new Hydraulic Brake Assist (HBA), which provides assistance in emergency braking situations.

Amazon FreeTime on Alexa includes a new set of parental controls and family - focused features such as explicit song filtering, bedtime limits, educational Q&A, household communications, positive reinforcement for using the word «please,» disabled voice purchasing, and more — for free

Since 2013, the subcommittee has orchestrated several successes and positive outcomes, some of which include: • Collaborating with the PIJAC Zoonosis committee to update the Healthy Herp Handling poster promoting healthy reptile and amphibian handling practices; develop the Zoonotic Disease Prevention Series for Retailers; draft informative store signage on how to prevent zoonotic diseases; participate in meetings on rodent and reptile disease transmission with the Centers for Disease Control; and produce and revise best management practices (BMP) documents; • Collaborating with the United States Association of Reptile Keepers on past and current attempts to pass legislation, ordinances, and regulatory activity that may impact herp ownership and related businesses; • Attending Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) meetings with reports and summary of actions affecting import and export of reptiles; • Addressing the 2013 Center for Biological Diversity petition to list 53 herp species under the Endangered Species Act; • Reviewing and commenting on the recent US Fish and Wildlife status review on the proposal to list wood turtles under the Endangered Species Act; • Submitting comments on proposed listing of flat - tailed tortoise and spider tortoise under the Endangered Species Act; • Introducing federal legislation in 2013 to allow for the export of certain constrictors listed as injurious in air shipments with aircraft that land in a state for refueling; • Providing volunteer support for auctions at 2013 National Reptile Breeders Expo and several North American Reptile Breeders Conferences; • Providing extensive consultation on constrictor caging standards in Ohio.

My study of dog bite - related fatalities occurring over the past five decades has identified the poor ownership / management practices involved in the overwhelming majority of these incidents: owners obtaining dogs, and maintaining them as resident dogs outside of regular, positive human interaction, often for negative functions (i.e. guarding / protection, fighting, intimidation / status); owners failing to humanely contain, control and maintain their dogs (chained dogs, loose roaming dogs, cases of abuse / neglect); owners failing to knowledgably supervise interaction between children and dogs; and owners failing to spay or neuter dogs not used for competition, show, or in a responsible breeding program.

Alice Burton works for Alley Cat Allies as the Animal Control and Shelter Liaison.She helps animal control officersand shelters talk about Trap - Neuter - Return (TNR) and what a positive impact it can make for communities and thControl and Shelter Liaison.She helps animal control officersand shelters talk about Trap - Neuter - Return (TNR) and what a positive impact it can make for communities and thcontrol officersand shelters talk about Trap - Neuter - Return (TNR) and what a positive impact it can make for communities and the cats.

During classes, she shows great control of the situations and is firm but positive in her response to the owners and dogs.You can tell she loves what she does as a career and it pays off for both the owners and dogs.

A complete list of affected and control dogs are given in supplemental Table S1 for the positive control loci as well as brachycephaly.

The alternative control schemes are an extremely positive design choice as it will certainly allow for players from different first - person shooter games to find the control scheme that is most comfortable for their play style.