Sentences with phrase «as a tumor marker»
Fishman, in particular, wanted to advance his studies in oncodevelopmental biology, exploiting proteins involved in embryonic development as tumor markers.
https://www.sbpdiscovery.org/
It is useful as a tumor marker to determine the extent of disease and its prognosis in persons with gastrointestinal and breast cancer.
Nagalase is used as a tumor marker, a marker of inflammation, and a marker of bacterial infection.
Not exact matches
His work indicates that this cell surface marker could serve as a target for a novel brain cancer vaccine or T - cell therapies engineered to recognize and kill tumors carrying that neoantigen.
As she was speaking, saying words like «multiple tumors on his liver,» «possible liver cancer» and «tumor markers,» I felt weak in the knees.
The pathologist of the Department of Pathology at the University Hospital of Bellvitge August Vidal explained that «this tumorigenic transformation depends on Dicer protein that could serve as a marker for the presence of tumor cells, or as a therapeutic target.»
«Pancreatic tumor - induced gene may prove beneficial as a drug marker.»
The scientists also found consistent evidence of increased pro-inflammatory markers, such as C - reactive protein and tumor necrosis factor alpha, associated with PTSD.
The key experiments included for replication were selected because they examine the induction of POSTN expression in the pulmonary stromal fibroblasts and test the role of POSTN in primary tumor formation and metastatic efficiency, which are relevant as the role of POSTN as a possible prognostic marker and target for anticancer therapies is explored (Xu et al., 2012; Nuzzo et al., 2014).
A marker in bile known as vascular endothelial growth factor (VEGF) plays an important role in the growth of cancerous tumors according to new research presented at the 78th Annual Scientific Meeting of the American College of Gastroenterology.
One group of small, non-coding RNA molecules could serve as a marker to improve cancer staging and may also be able to convert some advanced tumors to more treatable stages, report a University of Chicago - based research team in the April 1, 2008, issue of the journal Genes & Development.
The enzyme «isn't just a random by - product of a tumor — it's something that can serve as a marker for growth and malignancy,» says Ester Kwon, a former postdoctoral researcher in Bhatia's lab.
A lot of effort in tumor stem cell research has always been directed to finding a so - called marker, a molecule whose presence on a cell reliably identifies it as a cancer stem cell.
Aberrant expression of TUBB3 has also been found in various tumors of non-neural origin and can be used as a biomarker for cancer aggressiveness and a marker for the tendency to respond poorly to chemotherapy.
However, as demonstrated by a recent report from Stuelten and colleagues [13], the complexity of CSC markers continues to pose challenges for identifying and isolating the putative tumor stem cell populations by the cell - sorting approach.
The journal covers all aspects of surgical pathology, including classic diagnostic pathology, prognosis - related diagnosis (tumor stages, prognosis markers, such as MIB - percentage, hormone receptors, etc.), and therapy - related findings.
The laboratory currently pursues four integrated research objectives: 1) Defining how dynamic regulation of adhesion and migration controls metastasis, 2) Identification and characterization of the metastatic cell populations within a primary tumor, 3) Experimental modeling of metastasis in a clinically relevant manner, and 4) clinical implementation of molecular markers of migration as biomarkers of tumor progression and metastasis.
In a study involving 12 patients with bladder cancer, who also underwent prostate surgery as part of their treatment, she identified the ICOS molecule as the first immunologic marker identified in both tumor tissues and the systemic circulation that can be used as a biomarker for monitoring of anti-CTLA-4 treated patients as a possible marker of therapeutic activity.
Gb3 expression was detected independent of type (diffuse / intestinal), and was negatively correlated to increasing tumor - node - metastasis stages (P = 0.0385), as well as with markers for senescence.
This study design will establish whether (1) DAXX can serve as a marker for early tumor growth or later advanced / metastatic PCa, and (2) high DAXX expression associates with indolent versus lethal PCa.
We conducted a meta - analysis in nonmetastatic breast cancer patients treated by neoadjuvant chemotherapy (NCT) to assess the clinical validity of circulating tumor cell (CTC) detection as a prognostic marker.
Morgridge computational biologist John Steill, another co-author of the KinderMining study, is using the KinderMiner tool to improve gene marker lists, which have numerous uses such as classifying cells or samples by cell type and identifying samples that may produce tumors.
It has as yet to be verified whether magnesium intake is related to other global inflammatory markers, such as interleukin 6 (IL - 6) and tumor necrosis factor α (TNF - α).
The bacteria serves as a delivery system to introduce the cancer marker to the patient's immune system and instruct it to eliminate the tumor cells that express this marker.