Sentences with phrase «as a tumor progresses»

«Mutations are acquired over time as the tumor progresses and becomes more aggressive, more invasive, and more metastatic.

To develop new drugs and determine what treatments are most appropriate for different tumor stages, scientists need to work out what changes occur at a molecular and genetic level as a tumor progresses.

Sneezing and discharge will occur more often as the tumor progresses.

Not exact matches

According to this theory, tumor cells tend to «forget» the tissue from which they originated as the disease progresses, acquiring an undifferentiated phenotype associated with heightened aggressiveness and treatment resistance.

As prostate cancer progresses, tumor cells may infiltrate this periprostatic adipose tissue: this is a key step in the progression of this cancer, as it signals locally advanced disease (where the cancer can progress to nearby organsAs prostate cancer progresses, tumor cells may infiltrate this periprostatic adipose tissue: this is a key step in the progression of this cancer, as it signals locally advanced disease (where the cancer can progress to nearby organsas it signals locally advanced disease (where the cancer can progress to nearby organs).

The study — Genomic profiles of low - grade murine gliomas evolve during progression to glioblastoma — published April 7, shows how these tumors continue to rapidly evolve, becoming ever more genetically diverse, as they become malignant and progress.

Researchers developed models to examine the influence of driver mutations — mutations that promote cancer development — on the initiation and development of gliomas, and how tumor genomic profiles evolve as the cancer progresses.

Unlike other solid tumors, there has been limited progress in understanding the contribution of genetic risk factors to the development of uveal melanoma, researchers say, primarily due to the absence of comprehensive genetic data from patients as the large sample cohorts for this rare cancer type have not been available for research.

Although progress toward harnessing the immune system to attack tumors has been «enormous,» he said, his lab and many others are seeing in more and more studies — in lab mice as well as patients — that «immuno - oncology» will not be as simple as stimulating T cells to attack tumors.

The knowledge about how this cancer form arises and develops is still limited but new results from a research team led by Lene Uhrbom, Uppsala University / SciLifeLab, shows that disease progress and the malignancy are affected by the cell type from which the tumor originates as well as the age of the patient.

HHMI investigator Arul Chinnaiyan and colleagues at the University of Michigan showed that as prostate cancer develops and progresses, sarcosine levels increase in both tumor cells and urine samples, suggesting that measurements of the metabolite could aid in non-invasively diagnosing the disease.