This means that NF - κB, thought of
as a tumor promoter, also helps facilitate an immune response.»
A combination of hypoxia and messages from the tumor cells initiates a process whereby the newly arrived macrophages assume their bad - boy identity
as tumor promoters.
HIF1 - alpha functions
as a tumor promoter in cancer associated fibroblasts, and as a tumor suppressor in breast cancer cells: Autophagy drives compartment - specific oncogenesis
Not exact matches
TPA is a toxic chemical described
as «a potent
tumor promoter in mouse skin» by the Boston - based firm Cell Signaling Technology.
«Nobody ever looked for NPTX2
as a potential
tumor promoter in kidney cancer or any other cancer, from what we can tell,» says Dr. Radisky.
This cytokine they thought was a treatment for cancer was actually working
as an endogenous
tumor promoter.
Because DDX3 exhibits
tumor suppressor functions, such
as a growth - suppressive property and transcriptional activation of the p21waf1 / cip1
promoter, and is inactivated through down - regulation of gene expression or alteration of subcellular localization in
tumor cells, all these features together suggest that DDX3 might be a candidate
tumor suppressor.